Heart valve disorder
VeDDRA Code: 1515
193 adverse event reports referencing this reaction
193
Total Reports
79
Deaths
4090.0%
Death Rate
Species Most Affected
Dog 184
Cat 7
Cattle 2
Breeds Most Affected
Retriever - Labrador 16
Chihuahua 15
Crossbred Canine/dog 13
Retriever - Golden 9
Shepherd Dog - German 7
Dachshund (unspecified) 7
Shih Tzu 7
Terrier (unspecified) 6
Spitz - German Pomeranian 5
Spaniel - King Charles Cavalier 5
Associated Drugs
Milbemycin Oxime + Spinosad 46
Trilostane 17
Pimobendan 14
Moxidectin 13
Spinosad 12
Fluralaner Chew Tablets 12
Afoxolaner 12
Carprofen 11
Bedinvetmab 11
Ivermectin + Pyrantel As Pamoate Salt 9
Fluralaner 13.64% 12-Week Chew 9
Oclacitinib Maleate 8
Prednisone 7
Tramadol 6
Doxycycline 6
Buprenorphine 6
Gabapentin 6
Milbemycin Oxime + Praziquantel 6
Rabies Vaccine 5
Maropitant Citrate 5
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.