Reaction profile

The FDA adverse-event record for lack of efficacy (mycoplasma) - nos

94 FDA adverse-event reports reference lack of efficacy (mycoplasma) - nos (VeDDRA 2654). See the species, breeds, and drugs most associated with it below.

94
reports citing this reaction
67.0%
death-coded share
Cattle
most-affected species
Tulathromycin
most-associated drug
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94
Total Reports
63
Deaths
67.0%
Death Rate

Species Most Affected

Cattle 68
Dog 14
Cat 9
Chicken 1
Hedgehog 1
Duck 1

Breeds Most Affected

Mixed (Cattle) 34
Cattle (other) 23
Domestic Shorthair 8
Crossbred Bovine/Cattle 4
Cattle (unknown) 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Aberdeen Angus 2
Shepherd Dog - Australian 2
Chow Chow 1
Domestic Longhair 1

Associated Drugs

Tulathromycin 35
Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus 21
Ceftiofur Crystalline Free Acid 13
Bovine Viral Diarrhea Virus, Type 2, Strain 53637, Lot Bvd2Mlv-D;Bovine Viral Di 9
Gamithromycin 9
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra 9
Bovine Virus*5/Past M+Mh Lv/Lb 8
Sarolaner 5
Lotilaner 5
Milbemycin Oxime + Praziquantel 5
Bovine Viral Diarrhea Virus, Type 1, Strain Nadl-Sbvd, Msvx+1;Bovine Viral Diarr 5
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti 5
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid 4
Diflubenzuron And Permethrin 4
Trenbolone Acet/Estradiol Impl 4
Tildipirosin Injectable 4
Ceftiofur Hydrochloride 4
Selamectin;Sarolaner 3
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus 3
Bordetella Bronchiseptica Vaccine, Avirulent Live Culture 3

Lack of efficacy (mycoplasma) - NOS Reaction Insights

94 reports name Lack of efficacy (mycoplasma) - NOS; 63 recorded a death outcome (67.0% of reported events, not a population-level mortality rate). VeDDRA code: 2654.

By species: Cattle (68 reports), Dog (14 reports), Cat (9 reports). By breed: Mixed (Cattle) (34), Cattle (other) (23), Domestic Shorthair (8).

Most co-reported drugs: Tulathromycin (35 reports), Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus (21 reports), Ceftiofur Crystalline Free Acid (13 reports), Bovine Viral Diarrhea Virus, Type 2, Strain 53637, Lot Bvd2Mlv-D;Bovine Viral Di (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.