Reaction profile

The FDA adverse-event record for spondylitis

Name: Spondylitis - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

22 FDA reports name spondylitis, a lower-volume reaction in the CVM extract (VeDDRA 2244). Plate stamps and neighbourhood peers follow.

#2136 of 2,481
by report volume (all reactions): 22
reports citing this reaction: 18.2%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Spondylitis has 22 reports now versus 21 in that prior snapshot: 1 more (4.8%).

Report change: +1
Death-coded reports: +1
Death-coded share: +3.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Spondylitis changes

FDA AER · VeDDRA plate

Code 2244 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 22 reports
DEATH-ELEV 18.2%
LOWER-Q #2136/2481
PHOTO-FINISH Adenocarcinoma NOS
SPECIES-DOG Dog · 20
DRUG-LEAD Bedinvetmab · 7
DESK-WIDE 16 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Adenocarcinoma NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Spondylitis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Spondylitis

What the FDA AER plate says about Spondylitis

Signature read: 22 reports place Spondylitis in the lower third of FDA AER volume (#2136 of 2,481). Report volume is lower-third scale: 22 named reports in the openFDA extract. 4 of 22 reports were death-coded (18.2% of named reports, not a population mortality rate). Nearest volume peer: Adenocarcinoma NOS (±0 reports). Lead species Dog (20). Lead co-reported drug Bedinvetmab (7).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 20

Cat 2

Breeds Most Affected

Retriever - Labrador 4

Shepherd Dog - German 2

Retriever - Golden 2

Shepherd Dog - Australian 2

Siberian Husky 1

Chihuahua 1

Rottweiler 1

Terrier - Yorkshire 1

Schnauzer - Miniature 1

Dog (unknown) 1

Associated Drugs

Bedinvetmab 7

Oclacitinib Maleate 5

Grapiprant 4

Polysulfated Glycosaminoglycan 2

Milbemycin Oxime + Spinosad 2

Carprofen 2

Moxidectin 2

Sarolaner 2

Frunevetmab 2

Galliprant 2

Gabapentin 2

Amitriptyline 2

Desoxycorticosterone Pivalate 1

Fluralaner Chew Tablets 1

Thyroxine 1

Rimadyl 1

Interceptor 1

Vanguard Lyme 1

Dapp 1

Fluralaner 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Spondylitis (#2136 of 2,481 by report volume); death-coded 18.2%. PlainBreed reaction plate · report volume stamp 22 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →