Reaction profile

The FDA adverse-event record for prolonged capillary refill time

541 FDA reports name prolonged capillary refill time, a high-volume reaction in the CVM extract (VeDDRA 1937). Plate stamps and neighbourhood peers follow.

#613 of 2,481
by report volume (all reactions)
541
reports citing this reaction
29.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Prolonged capillary refill time has 541 reports now versus 524 in that prior snapshot: 17 more (3.2%).

Report change
+17
Death-coded reports
+5
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Prolonged capillary refill time changes

FDA AER · VeDDRA plate

Code 1937 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 541 reports
  • DEATH-HOT 29.8%
  • UPPER-Q #613/2481
  • PHOTO-FINISH Urination
  • SPECIES-DOG Dog · 477
  • DRUG-LEAD Moxidectin · 99
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Urination (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Prolonged capillary refill time

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Excoriation · near546Prolonged capillary r… · thi…541Urination · near541PR-LUNG(S), LESION(S) · near539Application site blee… · near536Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Prolonged capillary refill time

Prolonged capillary refill time: high death-coded share in the FDA AER plate

Signature read: 161 death-coded reports is a heavy tail count for Prolonged capillary refill time in the CVM extract. Report volume is upper-third scale: 541 named reports in the openFDA extract. Death-coded share is upper-third: 161 of 541 reports (29.8% of named reports). Nearest volume peer: Urination (±0 reports). Lead species Dog (477). Lead co-reported drug Moxidectin (99).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 477
Cat 41
Horse 22
Pig 1

Breeds Most Affected

Retriever - Labrador 47
Crossbred Canine/dog 32
Domestic Shorthair 29
Retriever - Golden 23
Boxer (German Boxer) 21
Dachshund (unspecified) 17
Chihuahua 15
Beagle 13
Terrier - Yorkshire 12
Shepherd Dog - German 12

Associated Drugs

Moxidectin 99
Milbemycin Oxime + Spinosad 55
Maropitant Citrate 49
Carprofen 46
Gabapentin 25
Rabies Virus, Kv 21
Melarsomine Dihydrochloride 20
Spinosad 20
Enrofloxacin 20
Deracoxib 19
Meloxicam 18
Buprenorphine 17
Dexamethasone 17
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 17
Bedinvetmab 17
Diphenhydramine Hcl 16
Metronidazole 16
Famotidine 15
Firocoxib 14
Tramadol 14

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Prolonged capillary refill time, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (541 here).

Similar death-coded share

Nearest other reactions by death-coded share (29.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Prolonged capillary refill time (#613 of 2,481 by report volume); death-coded 29.8%. PlainBreed reaction plate · death-coded report count stamp 161 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →