Decreased bowel movements

Verify with FDA CVM →

VeDDRA Code: 1939

790 adverse event reports referencing this reaction

790
Total Reports
132
Deaths
1670.0%
Death Rate

Species Most Affected

Dog 542
Cat 226
Horse 15
Rabbit 2
Unknown 1
Other Rodents 1
Human 1
Other Equids 1
Sheep 1

Breeds Most Affected

Domestic Shorthair 130
Chihuahua 45
Crossbred Canine/dog 45
Retriever - Labrador 42
Domestic Longhair 26
Terrier - Yorkshire 25
Shih Tzu 24
Domestic Mediumhair 21
Shepherd Dog - German 21
Retriever - Golden 20

Associated Drugs

Milbemycin Oxime + Spinosad 104
Maropitant Citrate 73
Carprofen 63
Afoxolaner 50
Cefovecin 43
Spinosad 37
Buprenorphine 35
Bedinvetmab 31
Famotidine 29
Gabapentin 28
Prednisone 27
Meloxicam 27
Ivermectin + Pyrantel As Pamoate Salt 25
Fluralaner 13.64% 12-Week Chew 23
Robenacoxib 21
Nitenpyram 21
Enrofloxacin 20
Imidacloprid + Moxidectin 18
Praziquantel 18
Fluralaner Chew Tablets 18

Data Summary

Metric Value
Total reports referencing reaction 790
Reports with fatal outcome 132
Case-fatality rate (reported events) 1670.0%
Species observed 9
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1939.

Decreased bowel movements Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 790 adverse event reports that reference Decreased bowel movements as a reaction term, including 132 reports with a death outcome — a 1670.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1939, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Decreased bowel movements appears most frequently in reports for Dog (542 reports), Cat (226 reports), Horse (15 reports) — with Dog dominating at 542 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (130), Chihuahua (45), Crossbred Canine/dog (45). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Decreased bowel movements are Milbemycin Oxime + Spinosad (104 reports), Maropitant Citrate (73 reports), Carprofen (63 reports), Afoxolaner (50 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 104 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial