Reaction profile

The FDA adverse-event record for ineffective, weight loss

127 FDA adverse-event reports reference ineffective, weight loss (VeDDRA 99949). See the species, breeds, and drugs most associated with it below.

127
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species
Dirlotapide
most-associated drug
Verify with FDA CVM →
127
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Dog 126
Cat 1

Breeds Most Affected

Crossbred Canine/dog 20
Dachshund (unspecified) 14
Chihuahua 10
Beagle 8
Retriever - Labrador 7
Spaniel - Cocker American 6
Sheepdog - Shetland 5
Spaniel - King Charles Cavalier 4
Retriever - Golden 4
Dog (unknown) 4

Associated Drugs

Dirlotapide 123
Prednisone 3
Carprofen 2
Levothyroxine Sodium 2
Cyclosporine 1
Ivermectin 1
Fipronil 1
Fluoxetine 1
Human Insulin 1
Deracoxib 1
Allergy 1
Tramadol 1
Alprazolam 1
Gabapentin 1
Famotidine 1
Meloxicam 1
Glucosamine & Chondroitin Sulfate 1
Omega-3 1
Glucosamine Hcl, Chondroitin Sulfate & Manganese 1
Phenylpropanolamine 1

INEFFECTIVE, WEIGHT LOSS Reaction Insights

127 reports name INEFFECTIVE, WEIGHT LOSS; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 99949.

By species: Dog (126 reports), Cat (1 reports). By breed: Crossbred Canine/dog (20), Dachshund (unspecified) (14), Chihuahua (10).

Most co-reported drugs: Dirlotapide (123 reports), Prednisone (3 reports), Carprofen (2 reports), Levothyroxine Sodium (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.