Reaction profile

The FDA adverse-event record for anoestrus

Name: Anoestrus - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

17 FDA reports name anoestrus, a lower-volume reaction in the CVM extract (VeDDRA 756). Plate stamps and neighbourhood peers follow.

#2233 of 2,481
by report volume (all reactions): 17
reports citing this reaction: 0.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Anoestrus has 17 reports now versus 17 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Anoestrus changes

FDA AER · VeDDRA plate

Code 756 VOL-TRACE

VOL-TRACE · DEATH-RARE · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 17 reports
DEATH-RARE 0.0%
LOWER-Q #2233/2481
PHOTO-FINISH Bone nonunion, medica…
SPECIES-DOG Dog · 6
DRUG-LEAD Spinosad · 3
DESK-WIDE 13 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Bone nonunion, medical device (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Anoestrus

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Anoestrus

Anoestrus: low death-coded share in the FDA AER plate

Signature read: Anoestrus's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 17 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 17 reports (0.0% of named reports). Nearest volume peer: Bone nonunion, medical device (±0 reports). Lead species Dog (6). Lead co-reported drug Spinosad (3).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 6

Pig 6

Cattle 5

Breeds Most Affected

Pig (unknown) 3

Spaniel - King Charles Cavalier 2

Cattle (other) 2

Bulldog 1

British White 1

Mixed (Pig) 1

Commercial hybrid 1

Red Angus 1

Coonhound - English 1

Terrier - Boston 1

Associated Drugs

Spinosad 3

Pregnyl/Gestyl 200/400 3

Milbemycin Oxime + Praziquantel 3

Cloprostenol 263 Inj Cattle 2

Melengestrol Acetate 2

Enrofloxacin 1

Pg 600 1

Dinoprost Tromethamine 1

Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 1

Altrenogest Oily Solution 1

Milbemycin Oxime 1

Afoxolaner 1

Oclacitinib Maleate 1

Altrenogest 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Anoestrus (#2233 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →