Reaction profile

The FDA adverse-event record for impaired vision

963 FDA reports name impaired vision, a high-volume reaction in the CVM extract (VeDDRA 407). Plate stamps and neighbourhood peers follow.

#405 of 2,481
by report volume (all reactions)
963
reports citing this reaction
15.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Impaired vision has 963 reports now versus 946 in that prior snapshot: 17 more (1.8%).

Report change
+17
Death-coded reports
+5
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Impaired vision changes

FDA AER · VeDDRA plate

Code 407 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 963 reports
  • DEATH-ELEV 15.5%
  • UPPER-Q #405/2481
  • PHOTO-FINISH Apnoea
  • SPECIES-DOG Dog · 712
  • DRUG-LEAD Milbemycin Oxime… · 90
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Apnoea (±4 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Impaired vision

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Rubbing · near969Apnoea · near967Necropsy performed · near967Impaired vision · this react…963Eye irritation · near955Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Impaired vision

What the FDA AER plate says about Impaired vision

Signature read: 149 death-coded reports is a heavy tail count for Impaired vision in the CVM extract. Report volume is upper-third scale: 963 named reports in the openFDA extract. 149 of 963 reports were death-coded (15.5% of named reports, not a population mortality rate). Nearest volume peer: Apnoea (±4 reports). Lead species Dog (712). Lead co-reported drug Milbemycin Oxime + Spinosad (90).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 712
Cat 210
Human 23
Horse 5
Cattle 5
Donkey 3
Goat 2
Other Birds 1
Other 1
Unknown 1

Breeds Most Affected

Domestic Shorthair 115
Retriever - Labrador 68
Crossbred Canine/dog 49
Terrier - Yorkshire 35
Chihuahua 31
Shih Tzu 26
Unknown 25
Dog (unknown) 22
Shepherd Dog - German 21
Shepherd Dog - Australian 20

Associated Drugs

Milbemycin Oxime + Spinosad 90
Bedinvetmab 68
Ivermectin 61
Enrofloxacin 60
Afoxolaner 59
Spinosad 57
Trilostane 37
Ivermectin + Pyrantel As Pamoate Salt 37
Carprofen 35
Maropitant Citrate 31
Imidacloprid + Moxidectin 30
Gabapentin 29
Fluralaner Chew Tablets 28
Cefovecin 25
Recombinant Human Insulin 25
Selamectin 24
Prednisone 23
Pyrantel Pamoate;Sarolaner 23
Frunevetmab 22
Sarolaner 21

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Impaired vision, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (963 here).

Similar death-coded share

Nearest other reactions by death-coded share (15.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Impaired vision (#405 of 2,481 by report volume); death-coded 15.5%. PlainBreed reaction plate · death-coded report count stamp 149 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →