Reaction profile

The FDA adverse-event record for acting tense

98 FDA adverse-event reports reference acting tense (VeDDRA 2206). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1403 of 2,481
by report volume (all reactions)
98
reports citing this reaction
3.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Acting tense has 98 reports now versus 95 in that prior snapshot: 3 more (3.2%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Acting tense changes

FDA AER · VeDDRA plate

Code 2206 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 98 reports
  • DEATH-LOW 3.1%
  • MID-PACK #1403/2481
  • PHOTO-FINISH Cranial nerve disorder
  • SPECIES-DOG Dog · 78
  • DRUG-LEAD Milbemycin Oxime… · 9
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cranial nerve disorder (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Acting tense

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acting tense · this reaction98Cranial nerve disorder · near98INEFFECTIVE, LICE SUC… · near98Product syringe impro… · near98Digestive tract steno… · near97Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Acting tense

Acting tense: low death-coded share in the FDA AER plate

Signature read: Acting tense's 3.1% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 3 of 98 reports (3.1% of named reports). Nearest volume peer: Cranial nerve disorder (±0 reports). Lead species Dog (78). Lead co-reported drug Milbemycin Oxime + Praziquantel (9).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Praziquantel appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 78
Cat 19
Human 1

Breeds Most Affected

Domestic Shorthair 11
Retriever - Labrador 9
Crossbred Canine/dog 8
Terrier (unspecified) 5
Dog (unknown) 4
Chihuahua 4
Siberian Husky 3
Maltese 3
Terrier - Jack Russell 3
Retriever - Golden 3

Associated Drugs

Milbemycin Oxime + Praziquantel 9
Buprenorphine 8
Selamectin 7
Maropitant Citrate 7
Gabapentin 7
Pyrantel Pamoate;Sarolaner 7
Dexmedetomidine 7
Ketamine 7
Afoxolaner 6
Carprofen 6
Propofol 6
Milbemycin Oxime + Spinosad 5
Fluralaner Chew Tablets 5
Sarolaner 5
Robenacoxib 5
Imidacloprid + Moxidectin 5
Fluralaner 13.64% 12-Week Chew 5
Fluid Therapy (Unknown) 5
Spinosad 4
Oclacitinib Maleate 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Acting tense, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (3.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Acting tense (#1403 of 2,481 by report volume); death-coded 3.1%. PlainBreed reaction plate · death-coded share stamp 3.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →