Abdominal effusion

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VeDDRA Code: 2164

445 adverse event reports referencing this reaction

445
Total Reports
250
Deaths
5620.0%
Death Rate

Species Most Affected

Dog 371
Cat 63
Horse 4
Cattle 3
Pig 2
Rabbit 1
Goat 1

Breeds Most Affected

Retriever - Labrador 81
Domestic Shorthair 31
Crossbred Canine/dog 30
Retriever - Golden 26
Shepherd Dog - German 14
Rottweiler 14
Terrier - Yorkshire 9
Chihuahua 7
Maine Coon 7
Bulldog 7

Associated Drugs

Maropitant Citrate 86
Carprofen 83
Deracoxib 47
Gabapentin 33
Moxidectin 29
Enrofloxacin 29
Meloxicam 26
Buprenorphine 25
Firocoxib 25
Oclacitinib Maleate 24
Fluralaner Chew Tablets 22
Tramadol 20
Famotidine 19
Fluralaner 13.64% 12-Week Chew 18
Isoflurane 17
Metronidazole 16
Ondansetron 16
Bedinvetmab 16
Milbemycin Oxime + Spinosad 14
Pantoprazole 14

Data Summary

Metric Value
Total reports referencing reaction 445
Reports with fatal outcome 250
Case-fatality rate (reported events) 5620.0%
Species observed 7
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2164.

Abdominal effusion Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 445 adverse event reports that reference Abdominal effusion as a reaction term, including 250 reports with a death outcome — a 5620.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2164, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Abdominal effusion appears most frequently in reports for Dog (371 reports), Cat (63 reports), Horse (4 reports) — with Dog dominating at 371 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (81), Domestic Shorthair (31), Crossbred Canine/dog (30). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Abdominal effusion are Maropitant Citrate (86 reports), Carprofen (83 reports), Deracoxib (47 reports), Gabapentin (33 reports), with Maropitant Citrate appearing alongside this reaction in 86 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial