Reaction profile

The FDA adverse-event record for increased borborygmus

550 FDA reports name increased borborygmus, a high-volume reaction in the CVM extract (VeDDRA 2091). Plate stamps and neighbourhood peers follow.

#607 of 2,481
by report volume (all reactions)
550
reports citing this reaction
2.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Increased borborygmus has 550 reports now versus 541 in that prior snapshot: 9 more (1.7%).

Report change
+9
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Increased borborygmus changes

FDA AER · VeDDRA plate

Code 2091 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 550 reports
  • DEATH-LOW 2.9%
  • UPPER-Q #607/2481
  • PHOTO-FINISH Fly biting behaviour
  • SPECIES-DOG Dog · 531
  • DRUG-LEAD Ivermectin + Pyra… · 51
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Fly biting behaviour (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Increased borborygmus

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Gastric ulcer · near551Fly biting behaviour · near550Increased borborygmus · this…550Pallor · near550Unexplained death · near550Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Increased borborygmus

Increased borborygmus: low death-coded share in the FDA AER plate

Signature read: Increased borborygmus's 2.9% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 550 named reports in the openFDA extract. Death-coded share is lower-third: 16 of 550 reports (2.9% of named reports). Nearest volume peer: Fly biting behaviour (±0 reports). Lead species Dog (531). Lead co-reported drug Ivermectin + Pyrantel As Pamoate Salt (51).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ivermectin + Pyrantel As Pamoate Salt appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 531
Cat 13
Horse 5
Human 1

Breeds Most Affected

Retriever - Labrador 36
Crossbred Canine/dog 36
Chihuahua 35
Boxer (German Boxer) 23
Terrier - Yorkshire 22
Retriever - Golden 17
Dog (unknown) 15
Beagle 15
Shepherd Dog - German 14
Shih Tzu 14

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 51
Milbemycin Oxime + Spinosad 50
Afoxolaner 50
Fluralaner Chew Tablets 28
Grapiprant 22
Pyrantel Pamoate;Sarolaner 22
Lufenuron + Milbemycin Oxime 20
Milbemycin Oxime + Praziquantel 20
Moxidectin 19
Oclacitinib Maleate 18
Milbemycin Oxime 17
Milbemycin Oxime, Lufenuron 17
Sarolaner 17
Carprofen 16
Bedinvetmab 14
Maropitant Citrate 13
Gabapentin 13
Trilostane 12
Imidacloprid + Moxidectin 12
Spinosad 11

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Increased borborygmus, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (550 here).

Similar death-coded share

Nearest other reactions by death-coded share (2.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Increased borborygmus (#607 of 2,481 by report volume); death-coded 2.9%. PlainBreed reaction plate · death-coded share stamp 2.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →