Labelled drug-drug interaction medication error
VeDDRA Code: 99842
621 adverse event reports referencing this reaction
621
Total Reports
82
Deaths
1320.0%
Death Rate
Species Most Affected
Dog 563
Cat 52
Horse 3
Human 2
Pig 1
Breeds Most Affected
Crossbred Canine/dog 87
Retriever - Labrador 75
Shepherd Dog - German 25
Dog (unknown) 21
Bulldog 21
Chihuahua 20
Retriever - Golden 19
Pit Bull 19
Domestic (unspecified) 18
Shih Tzu 16
Associated Drugs
Spinosad 209
Ivermectin 164
Milbemycin Oxime + Spinosad 114
Cyclosporine 100
Carprofen 52
Firocoxib 31
Meloxicam 23
Dexmedetomidine Hydrochloride 17
Deracoxib 17
Cefovecin Sodium 16
Spinosad, Milbemycin 13
Robenacoxib 13
Cephalexin 9
Grapiprant 7
Prednisone 6
Ketoconazole 5
Ketoprofen 4
Tramadol 4
Maropitant 3
Vaccines (Unknown) 3
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.