Reaction profile

The FDA adverse-event record for pr-pleura, lesion(s)

24 FDA adverse-event reports reference pr-pleura, lesion(s) (VeDDRA 99667). See the species, breeds, and drugs most associated with it below.

24
reports citing this reaction
100.0%
death-coded share
Cattle
most-affected species
Florfenicol, Flunixin
most-associated drug
Verify with FDA CVM →
24
Total Reports
24
Deaths
100.0%
Death Rate

Species Most Affected

Cattle 11
Dog 7
Cat 6

Breeds Most Affected

Holstein-Friesian also known as Holstein 7
Crossbred Canine/dog 3
Domestic (unspecified) 3
Crossbred Bovine/Cattle 2
Domestic Shorthair 2
Cattle (other) 1
Cattle (unknown) 1
Deutsche Dogge, Great Dane 1
Akita 1
Collie - Border 1

Associated Drugs

Florfenicol, Flunixin 4
Tildipirosin 3
Cefovecin 3
Maropitant 2
Cefovecin Sodium 2
Moxidectin 2
Fenbendazole 2
Milbemycin 1
Tylosin 1
Gamithromycin 15% 1
Amoxicillin, Clavulanate 1
Meloxicam 1
Vitamin B12 1
Calcium Gluconate 1
Enrofloxacin 1
Furosemide 1
Oclacitinib Maleate 1
Marbofloxacin 1
Anti-Il31 Mab Mcs Lot #1283563 1
Dexamethasone 1

PR-PLEURA, LESION(S) Reaction Insights

24 reports name PR-PLEURA, LESION(S); 24 recorded a death outcome (100.0% of reported events, not a population-level mortality rate). VeDDRA code: 99667.

By species: Cattle (11 reports), Dog (7 reports), Cat (6 reports). By breed: Holstein-Friesian also known as Holstein (7), Crossbred Canine/dog (3), Domestic (unspecified) (3).

Most co-reported drugs: Florfenicol, Flunixin (4 reports), Tildipirosin (3 reports), Cefovecin (3 reports), Maropitant (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.