Reaction profile

The FDA adverse-event record for pr-pleura, lesion(s)

Name: PR-PLEURA, LESION(S) - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

24 FDA reports name pr-pleura, lesion(s), a lower-volume reaction in the CVM extract (VeDDRA 99667). Plate stamps and neighbourhood peers follow.

#2092 of 2,481
by report volume (all reactions): 24
reports citing this reaction: 100.0%
death-coded share: Cattle
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-PLEURA, LESION(S) has 24 reports now versus 24 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-PLEURA, LESION(S) changes

FDA AER · VeDDRA plate

Code 99667 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 24 reports
DEATH-HOT 100.0%
LOWER-Q #2092/2481
PHOTO-FINISH Acute pancreatitis
SPECIES-CATTLE Cattle · 11
DRUG-LEAD Florfenicol, Flun… · 4
DESK-WIDE 12 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Acute pancreatitis (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-PLEURA, LESION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around PR-PLEURA, LESION(S)

PR-PLEURA, LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-PLEURA, LESION(S)'s 100.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 24 named reports in the openFDA extract. Death-coded share is upper-third: 24 of 24 reports (100.0% of named reports). Nearest volume peer: Acute pancreatitis (±0 reports). Lead species Cattle (11). Lead co-reported drug Florfenicol, Flunixin (4).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 11

Dog 7

Cat 6

Breeds Most Affected

Holstein-Friesian also known as Holstein 7

Crossbred Canine/dog 3

Domestic (unspecified) 3

Crossbred Bovine/Cattle 2

Domestic Shorthair 2

Cattle (other) 1

Cattle (unknown) 1

Deutsche Dogge, Great Dane 1

Akita 1

Collie - Border 1

Associated Drugs

Florfenicol, Flunixin 4

Tildipirosin 3

Cefovecin 3

Maropitant 2

Cefovecin Sodium 2

Moxidectin 2

Fenbendazole 2

Milbemycin 1

Tylosin 1

Gamithromycin 15% 1

Amoxicillin, Clavulanate 1

Meloxicam 1

Vitamin B12 1

Calcium Gluconate 1

Enrofloxacin 1

Furosemide 1

Oclacitinib Maleate 1

Marbofloxacin 1

Anti-Il31 Mab Mcs Lot #1283563 1

Dexamethasone 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-PLEURA, LESION(S) (#2092 of 2,481 by report volume); death-coded 100.0%. PlainBreed reaction plate · death-coded share stamp 100.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →