Reaction profile

The FDA adverse-event record for hyperaemia

105 FDA adverse-event reports reference hyperaemia (VeDDRA 1008). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1367 of 2,481
by report volume (all reactions)
105
reports citing this reaction
19.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hyperaemia has 105 reports now versus 102 in that prior snapshot: 3 more (2.9%).

Report change
+3
Death-coded reports
+1
Death-coded share
+0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hyperaemia changes

FDA AER · VeDDRA plate

Code 1008 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 105 reports
  • DEATH-ELEV 19.0%
  • MID-PACK #1367/2481
  • PHOTO-FINISH Decreased mean corpus…
  • SPECIES-DOG Dog · 84
  • DRUG-LEAD Moxidectin · 14
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Decreased mean corpuscular haemoglobin concentration (MCHC) (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Hyperaemia

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Decreased mean corpus… · near105Hyperaemia · this reaction105Injection site stiffn… · near105Lack of efficacy (neo… · near105Pyometra · near105Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hyperaemia

What the FDA AER plate says about Hyperaemia

Signature read: death-coded share at 19.0% is the most distinctive outcome stamp on Hyperaemia. Report volume sits in the middle third of the reaction corpus. 20 of 105 reports were death-coded (19.0% of named reports, not a population mortality rate). Nearest volume peer: Decreased mean corpuscular haemoglobin concentration (MCHC) (±0 reports). Lead species Dog (84). Lead co-reported drug Moxidectin (14).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 84
Cat 12
Horse 3
Pig 3
Cattle 2
Sheep 1

Breeds Most Affected

Retriever - Labrador 13
Domestic Shorthair 9
Crossbred Canine/dog 7
Terrier - Bull - American Pit 6
Boxer (German Boxer) 5
Chihuahua 4
Pit Bull 3
Shih Tzu 3
Dog (unknown) 3
Poodle - Standard 2

Associated Drugs

Moxidectin 14
Enrofloxacin 10
Carprofen 9
Maropitant Citrate 9
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 9
Gabapentin 8
Prednisone 7
Oclacitinib Maleate 6
Meloxicam 5
Milbemycin Oxime + Spinosad 5
Cefovecin 5
Ear Flush 5
Pilocarpine 5
Afoxolaner 4
Melarsomine Dihydrochloride 4
Diphenhydramine Injection 4
Ear Cleaner 4
Imidacloprid + Moxidectin 3
Cefpodoxime Proxetil 3
Spinosad 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hyperaemia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hyperaemia (#1367 of 2,481 by report volume); death-coded 19.0%. PlainBreed reaction plate · death-coded share stamp 19.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →