Reaction profile

The FDA adverse-event record for hyperaemia

98 FDA adverse-event reports reference hyperaemia (VeDDRA 1008). See the species, breeds, and drugs most associated with it below.

98
reports citing this reaction
19.4%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
98
Total Reports
19
Deaths
19.4%
Death Rate

Species Most Affected

Dog 77
Cat 12
Horse 3
Pig 3
Cattle 2
Sheep 1

Breeds Most Affected

Retriever - Labrador 11
Domestic Shorthair 9
Terrier - Bull - American Pit 6
Boxer (German Boxer) 5
Crossbred Canine/dog 5
Chihuahua 4
Pit Bull 3
Shih Tzu 3
Dog (unknown) 3
Poodle - Standard 2

Associated Drugs

Moxidectin 12
Enrofloxacin 10
Carprofen 9
Maropitant Citrate 9
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 9
Gabapentin 8
Prednisone 7
Oclacitinib Maleate 6
Meloxicam 5
Milbemycin Oxime + Spinosad 5
Cefovecin 5
Ear Flush 5
Pilocarpine 5
Afoxolaner 4
Melarsomine Dihydrochloride 4
Diphenhydramine Injection 4
Ear Cleaner 4
Imidacloprid + Moxidectin 3
Cefpodoxime Proxetil 3
Spinosad 3

Hyperaemia Reaction Insights

98 reports name Hyperaemia; 19 recorded a death outcome (19.4% of reported events, not a population-level mortality rate). VeDDRA code: 1008.

By species: Dog (77 reports), Cat (12 reports), Horse (3 reports). By breed: Retriever - Labrador (11), Domestic Shorthair (9), Terrier - Bull - American Pit (6).

Most co-reported drugs: Moxidectin (12 reports), Enrofloxacin (10 reports), Carprofen (9 reports), Maropitant Citrate (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.