Facial paralysis

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VeDDRA Code: 1144

515 adverse event reports referencing this reaction

515
Total Reports
48
Deaths
930.0%
Death Rate

Species Most Affected

Dog 457
Cat 35
Horse 16
Cattle 3
Human 3
Sheep 1

Breeds Most Affected

Retriever - Labrador 39
Boxer (German Boxer) 29
Bulldog - French 28
Retriever - Golden 26
Crossbred Canine/dog 25
Domestic Shorthair 23
Terrier - Bull - American Pit 21
Beagle 20
Pit Bull 18
Dog (unknown) 18

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 91
Trilostane 50
Bedinvetmab 38
Carprofen 37
Maropitant Citrate 31
Oclacitinib Maleate 30
Milbemycin Oxime + Spinosad 28
Prednisone 28
Gabapentin 27
Moxidectin 18
Enrofloxacin 17
Fluralaner Chew Tablets 15
Melarsomine Dihydrochloride 14
Doxycycline 14
Sarolaner 14
Pyrantel Pamoate;Sarolaner 14
Cyclosporine 13
Afoxolaner 13
Fluralaner 13.64% 12-Week Chew 13
Spinosad 12

Data Summary

Metric Value
Total reports referencing reaction 515
Reports with fatal outcome 48
Case-fatality rate (reported events) 930.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1144.

Facial paralysis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 515 adverse event reports that reference Facial paralysis as a reaction term, including 48 reports with a death outcome — a 930.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1144, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Facial paralysis appears most frequently in reports for Dog (457 reports), Cat (35 reports), Horse (16 reports) — with Dog dominating at 457 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (39), Boxer (German Boxer) (29), Bulldog - French (28). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Facial paralysis are Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (91 reports), Trilostane (50 reports), Bedinvetmab (38 reports), Carprofen (37 reports), with Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appearing alongside this reaction in 91 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial