Reaction profile

The FDA adverse-event record for facial paralysis

515 FDA adverse-event reports reference facial paralysis (VeDDRA 1144). See the species, breeds, and drugs most associated with it below.

515
reports citing this reaction
9.3%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
515
Total Reports
48
Deaths
9.3%
Death Rate

Species Most Affected

Dog 457
Cat 35
Horse 16
Cattle 3
Human 3
Sheep 1

Breeds Most Affected

Retriever - Labrador 39
Boxer (German Boxer) 29
Bulldog - French 28
Retriever - Golden 26
Crossbred Canine/dog 25
Domestic Shorthair 23
Terrier - Bull - American Pit 21
Beagle 20
Pit Bull 18
Dog (unknown) 18

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 91
Trilostane 50
Bedinvetmab 38
Carprofen 37
Maropitant Citrate 31
Oclacitinib Maleate 30
Milbemycin Oxime + Spinosad 28
Prednisone 28
Gabapentin 27
Moxidectin 18
Enrofloxacin 17
Fluralaner Chew Tablets 15
Melarsomine Dihydrochloride 14
Doxycycline 14
Sarolaner 14
Pyrantel Pamoate;Sarolaner 14
Cyclosporine 13
Afoxolaner 13
Fluralaner 13.64% 12-Week Chew 13
Spinosad 12

Facial paralysis Reaction Insights

515 reports name Facial paralysis; 48 recorded a death outcome (9.3% of reported events, not a population-level mortality rate). VeDDRA code: 1144.

By species: Dog (457 reports), Cat (35 reports), Horse (16 reports). By breed: Retriever - Labrador (39), Boxer (German Boxer) (29), Bulldog - French (28).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (91 reports), Trilostane (50 reports), Bedinvetmab (38 reports), Carprofen (37 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.