Reaction profile

The FDA adverse-event record for licking at application site

1,049 FDA reports name licking at application site, a high-volume reaction in the CVM extract (VeDDRA 1973). Plate stamps and neighbourhood peers follow.

#381 of 2,481
by report volume (all reactions)
1,049
reports citing this reaction
1.1%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Licking at application site has 1,049 reports now versus 1,035 in that prior snapshot: 14 more (1.4%).

Report change
+14
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Licking at application site changes

FDA AER · VeDDRA plate

Code 1973 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,049 reports
  • DEATH-LOW 1.1%
  • UPPER-Q #381/2481
  • PHOTO-FINISH Eye redness
  • SPECIES-CAT Cat · 947
  • DRUG-LEAD Imidacloprid + Mo… · 239
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Eye redness (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Licking at application site

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Elevated creatine-kin… · near1053Discoloured urine · near1051Eye redness · near1050Licking at applicatio… · thi…1049Wound · near1048Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Licking at application site

Licking at application site: low death-coded share in the FDA AER plate

Signature read: Licking at application site's 1.1% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 1,049 named reports in the openFDA extract. Death-coded share is lower-third: 12 of 1,049 reports (1.1% of named reports). Nearest volume peer: Eye redness (±1 reports). Lead species Cat (947). Lead co-reported drug Imidacloprid + Moxidectin (239).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Imidacloprid + Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 947
Dog 96
Cattle 3
Horse 3

Breeds Most Affected

Domestic Shorthair 624
Cat (unknown) 97
Domestic Longhair 67
Domestic Mediumhair 51
Siamese 29
Cat (other) 13
Crossbred Canine/dog 9
American Shorthair 9
Bengal 9
Dog (unknown) 8

Associated Drugs

Imidacloprid + Moxidectin 239
Emodepside + Praziquantel 223
Fluralaner Spot-On Solution 201
Eprinomectin + Esafoxolaner + Praziquantel 105
Selamectin 78
Fluralaner/Moxidectin Spot-On 47
Selamectin;Sarolaner 41
Eprinomectin + Praziquantel 12
Chlorhexidine + Ophytrium 11
Buprenorphine 10
Flumethrin-Imidacloprid 7
Rabies Vaccine 7
Nitenpyram 7
Imidacloprid + Pyriproxyfen 6
Ivermectin + Pyrantel As Pamoate Salt 6
Dexmedetomidine 6
Robenacoxib 6
Cefovecin Sodium 6
Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide 6
Gabapentin 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Licking at application site, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,049 here).

Similar death-coded share

Nearest other reactions by death-coded share (1.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Licking at application site (#381 of 2,481 by report volume); death-coded 1.1%. PlainBreed reaction plate · death-coded share stamp 1.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →