Reaction profile

The FDA adverse-event record for staggering

1,413 FDA reports name staggering, a high-volume reaction in the CVM extract (VeDDRA 655). Plate stamps and neighbourhood peers follow.

#300 of 2,481
by report volume (all reactions)
1,413
reports citing this reaction
17.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Staggering has 1,413 reports now versus 1,401 in that prior snapshot: 12 more (0.9%).

Report change
+12
Death-coded reports
+4
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Staggering changes

FDA AER · VeDDRA plate

Code 655 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,413 reports
  • DEATH-ELEV 17.0%
  • UPPER-Q #300/2481
  • PHOTO-FINISH Shivering
  • SPECIES-DOG Dog · 1,117
  • DRUG-LEAD Milbemycin Oxime… · 161
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Shivering (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Staggering

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Excessive licking and… · near1417Hypercalcaemia · near1415Administration error… · near1414Shivering · near1413Staggering · this reaction1413Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Staggering

What the FDA AER plate says about Staggering

Signature read: 240 death-coded reports is a heavy tail count for Staggering in the CVM extract. Report volume is upper-third scale: 1,413 named reports in the openFDA extract. 240 of 1,413 reports were death-coded (17.0% of named reports, not a population mortality rate). Nearest volume peer: Shivering (±0 reports). Lead species Dog (1,117). Lead co-reported drug Milbemycin Oxime + Spinosad (161).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,117
Cat 190
Cattle 69
Horse 26
Sheep 4
Goat 3
Human 2
Other Birds 1
Donkey 1

Breeds Most Affected

Retriever - Labrador 130
Domestic Shorthair 118
Crossbred Canine/dog 97
Chihuahua 52
Terrier - Yorkshire 50
Shepherd Dog - German 49
Retriever - Golden 42
Shih Tzu 39
Dog (unknown) 34
Boxer (German Boxer) 28

Associated Drugs

Milbemycin Oxime + Spinosad 161
Ivermectin + Pyrantel As Pamoate Salt 121
Spinosad 110
Afoxolaner 94
Carprofen 90
Bedinvetmab 55
Fluralaner Chew Tablets 47
Ivermectin 45
Moxidectin 41
Maropitant Citrate 34
Cefovecin 31
Sarolaner 28
Selamectin 27
Milbemycin Oxime + Praziquantel 25
Ivermectin, Pyrantel 23
Gabapentin 23
Pyrantel Pamoate;Sarolaner 23
Insulin Injectable Vial 20
Fluralaner 13.64% 12-Week Chew 18
Trilostane 17

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Staggering, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,413 here).

Similar death-coded share

Nearest other reactions by death-coded share (17.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Staggering (#300 of 2,481 by report volume); death-coded 17.0%. PlainBreed reaction plate · death-coded report count stamp 240 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →