Reaction profile

The FDA adverse-event record for star-gazing

904 FDA reports name star-gazing, a high-volume reaction in the CVM extract (VeDDRA 2246). Plate stamps and neighbourhood peers follow.

#424 of 2,481
by report volume (all reactions)
904
reports citing this reaction
4.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Star-gazing has 904 reports now versus 900 in that prior snapshot: 4 more (0.4%).

Report change
+4
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Star-gazing changes

FDA AER · VeDDRA plate

Code 2246 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 904 reports
  • DEATH-LOW 4.4%
  • UPPER-Q #424/2481
  • PHOTO-FINISH Lying down
  • SPECIES-DOG Dog · 850
  • DRUG-LEAD Milbemycin Oxime… · 640
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lying down (±4 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Star-gazing

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site burn · near911Lying down · near908Star-gazing · this reaction904Application site reac… · near897Biting -aggression (s… · near896Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Star-gazing

Star-gazing: low death-coded share in the FDA AER plate

Signature read: 904 reports place Star-gazing in the upper third of FDA AER volume (#424 of 2,481). Report volume is upper-third scale: 904 named reports in the openFDA extract. Death-coded share is lower-third: 40 of 904 reports (4.4% of named reports). Nearest volume peer: Lying down (±4 reports). Lead species Dog (850). Lead co-reported drug Milbemycin Oxime + Spinosad (640).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 850
Cat 48
Horse 3
Cattle 2
Rat 1

Breeds Most Affected

Chihuahua 77
Maltese 73
Terrier - Yorkshire 71
Crossbred Canine/dog 53
Retriever - Labrador 40
Retriever - Golden 35
Shih Tzu 33
Boxer (German Boxer) 25
Domestic Shorthair 25
Pug 23

Associated Drugs

Milbemycin Oxime + Spinosad 640
Spinosad 73
Afoxolaner 48
Ivermectin + Pyrantel As Pamoate Salt 26
Fluralaner Chew Tablets 25
Trilostane 22
Sarolaner 20
Oclacitinib Maleate 18
Buprenorphine 18
Carprofen 16
Moxidectin 14
Ivermectin 13
Maropitant Citrate 13
Selamectin 10
Cefovecin 10
Bordetella Vaccine 9
Milbemycin Oxime 9
Milbemycin Oxime, Lufenuron 8
Milbemycin Oxime + Praziquantel 8
Pyrantel Pamoate;Sarolaner 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Star-gazing, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (4.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Star-gazing (#424 of 2,481 by report volume); death-coded 4.4%. PlainBreed reaction plate · report volume stamp 904 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →