Reaction profile

The FDA adverse-event record for itchy ears

207 FDA adverse-event reports reference itchy ears (VeDDRA 2572). See the species, breeds, and drugs most associated with it below.

207
reports citing this reaction
1.4%
death-coded share
Dog
most-affected species
Pyrantel Pamoate;Sarolaner
most-associated drug
Verify with FDA CVM →
207
Total Reports
3
Deaths
1.4%
Death Rate

Species Most Affected

Dog 155
Cat 49
Human 2
Ferret 1

Breeds Most Affected

Domestic Shorthair 36
Retriever - Labrador 17
Crossbred Canine/dog 17
Chihuahua 11
Retriever - Golden 10
Dog (unknown) 7
Shepherd Dog - German 7
Dachshund (unspecified) 5
Shih Tzu 5
Boxer (German Boxer) 4

Associated Drugs

Pyrantel Pamoate;Sarolaner 25
Afoxolaner 18
Frunevetmab 14
Milbemycin Oxime + Spinosad 12
Moxidectin 12
Oclacitinib Maleate 10
Prednisone 9
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 9
Fluralaner Chew Tablets 7
Carprofen 7
Genta/Momet/Clotrim Ear Oint 6
Imidacloprid + Moxidectin 6
Nitenpyram 6
Ivermectin + Pyrantel As Pamoate Salt 6
Orbiflox/Momet/Posaco Eardrops 6
Betamethasone + Florfenicol + Terbinafine 5
Dexamethasone Sodium Phosphate 5
Selamectin;Sarolaner 5
Milbemycin Oxime + Praziquantel 5
Fluralaner Spot-On Solution 4

Itchy ears Reaction Insights

207 reports name Itchy ears; 3 recorded a death outcome (1.4% of reported events, not a population-level mortality rate). VeDDRA code: 2572.

By species: Dog (155 reports), Cat (49 reports), Human (2 reports). By breed: Domestic Shorthair (36), Retriever - Labrador (17), Crossbred Canine/dog (17).

Most co-reported drugs: Pyrantel Pamoate;Sarolaner (25 reports), Afoxolaner (18 reports), Frunevetmab (14 reports), Milbemycin Oxime + Spinosad (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.