Reaction profile

The FDA adverse-event record for belching

155 FDA adverse-event reports reference belching (VeDDRA 337). See the species, breeds, and drugs most associated with it below.

155
reports citing this reaction
5.8%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
155
Total Reports
9
Deaths
5.8%
Death Rate

Species Most Affected

Dog 141
Human 7
Cat 6
Horse 1

Breeds Most Affected

Retriever - Labrador 15
Crossbred Canine/dog 12
Retriever - Golden 11
Unknown 7
Chihuahua 6
Shih Tzu 6
Pit Bull 6
Dog (unknown) 5
Shepherd Dog - German 4
Maltese 4

Associated Drugs

Milbemycin Oxime + Spinosad 41
Maropitant Citrate 19
Spinosad 14
Famotidine 10
Carprofen 10
Tramadol 8
Oclacitinib Maleate 8
Fluralaner Chew Tablets 8
Deracoxib 7
Enrofloxacin 7
Prednisone 7
Afoxolaner 7
Milbemycin Oxime + Praziquantel 6
Buprenorphine 5
Cyclosporine A 5
Selamectin 5
Sucralfate 5
Polysulfated Glycosaminoglycan 4
Trazodone 4
Metoclopramide 4

Belching Reaction Insights

155 reports name Belching; 9 recorded a death outcome (5.8% of reported events, not a population-level mortality rate). VeDDRA code: 337.

By species: Dog (141 reports), Human (7 reports), Cat (6 reports). By breed: Retriever - Labrador (15), Crossbred Canine/dog (12), Retriever - Golden (11).

Most co-reported drugs: Milbemycin Oxime + Spinosad (41 reports), Maropitant Citrate (19 reports), Spinosad (14 reports), Famotidine (10 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.