Reaction profile

The FDA adverse-event record for choke

171 FDA adverse-event reports reference choke (VeDDRA 2584). See the species, breeds, and drugs most associated with it below.

171
reports citing this reaction
24.0%
death-coded share
Dog
most-affected species
Afoxolaner
most-associated drug
Verify with FDA CVM →
171
Total Reports
41
Deaths
24.0%
Death Rate

Species Most Affected

Dog 133
Cat 24
Horse 10
Cattle 2
Human 1
Chicken 1

Breeds Most Affected

Domestic Shorthair 19
Retriever - Labrador 11
Shih Tzu 10
Shepherd Dog - German 9
Crossbred Canine/dog 9
Dog (unknown) 9
Chihuahua 8
Terrier - Yorkshire 8
Maltese 7
Spitz - German Pomeranian 6

Associated Drugs

Afoxolaner 23
Ivermectin + Pyrantel As Pamoate Salt 16
Fluralaner 13.64% 12-Week Chew 15
Pyrantel Pamoate;Sarolaner 11
Maropitant Citrate 8
Oclacitinib Maleate 6
Cefovecin 6
Milbemycin Oxime + Spinosad 5
Ivermectin + Praziquantel 5
Moxidectin 5
Carprofen 5
Famotidine 4
Fluralaner Spot-On Solution 4
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 4
Imidacloprid + Moxidectin 4
Lotilaner 4
Bedinvetmab 4
Spinosad 3
Anti-Il31 Mab Mcs Lot #1283563 3
Selamectin 3

Choke Reaction Insights

171 reports name Choke; 41 recorded a death outcome (24.0% of reported events, not a population-level mortality rate). VeDDRA code: 2584.

By species: Dog (133 reports), Cat (24 reports), Horse (10 reports). By breed: Domestic Shorthair (19), Retriever - Labrador (11), Shih Tzu (10).

Most co-reported drugs: Afoxolaner (23 reports), Ivermectin + Pyrantel As Pamoate Salt (16 reports), Fluralaner 13.64% 12-Week Chew (15 reports), Pyrantel Pamoate;Sarolaner (11 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.