Reaction profile

The FDA adverse-event record for choke

177 FDA adverse-event reports reference choke (VeDDRA 2584). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1096 of 2,481
by report volume (all reactions)
177
reports citing this reaction
23.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Choke has 177 reports now versus 174 in that prior snapshot: 3 more (1.7%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Choke changes

FDA AER · VeDDRA plate

Code 2584 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 177 reports
  • DEATH-HOT 23.2%
  • MID-PACK #1096/2481
  • PHOTO-FINISH Decreased respiratory…
  • SPECIES-DOG Dog · 139
  • DRUG-LEAD Afoxolaner · 23
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Decreased respiratory rate (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Choke

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Choke · this reaction177Decreased respiratory… · near177Ptyalism · near177Vascular disorder NOS… · near177Agonal breathing · near176Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Choke

What the FDA AER plate says about Choke

Signature read: 41 death-coded reports is a heavy tail count for Choke in the CVM extract. Report volume sits in the middle third of the reaction corpus. 41 of 177 reports were death-coded (23.2% of named reports, not a population mortality rate). Nearest volume peer: Decreased respiratory rate (±0 reports). Lead species Dog (139). Lead co-reported drug Afoxolaner (23).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Afoxolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 139
Cat 24
Horse 10
Cattle 2
Human 1
Chicken 1

Breeds Most Affected

Domestic Shorthair 19
Retriever - Labrador 11
Shih Tzu 10
Dog (unknown) 10
Shepherd Dog - German 9
Chihuahua 9
Crossbred Canine/dog 9
Terrier - Yorkshire 8
Maltese 7
Spitz - German Pomeranian 6

Associated Drugs

Afoxolaner 23
Ivermectin + Pyrantel As Pamoate Salt 16
Fluralaner 13.64% 12-Week Chew 15
Pyrantel Pamoate;Sarolaner 12
Oclacitinib Maleate 8
Maropitant Citrate 8
Cefovecin 6
Milbemycin Oxime + Spinosad 5
Carprofen 5
Moxidectin 5
Ivermectin + Praziquantel 5
Famotidine 4
Fluralaner Spot-On Solution 4
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 4
Imidacloprid + Moxidectin 4
Lotilaner 4
Bedinvetmab 4
Ilunocitinib 4
Spinosad 3
Anti-Il31 Mab Mcs Lot #1283563 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Choke, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (23.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Choke (#1096 of 2,481 by report volume); death-coded 23.2%. PlainBreed reaction plate · death-coded report count stamp 41 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →