Reaction profile

The FDA adverse-event record for chest discomfort nos

51 FDA adverse-event reports reference chest discomfort nos (VeDDRA 1263). See the species, breeds, and drugs most associated with it below.

51
reports citing this reaction
0.0%
death-coded share
Human
most-affected species
Tilmicosin
most-associated drug
Verify with FDA CVM →
51
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Human 44
Dog 5
Horse 2

Breeds Most Affected

Unknown 44
Pit Bull 2
Spaniel - Springer English 1
Terrier (unspecified) 1
Thoroughbred 1
Horse (unknown) 1
Terrier - Yorkshire 1

Associated Drugs

Tilmicosin 10
Milbemycin Oxime + Spinosad 7
Tilmicosin Phosphate 5
Nitenpyram 5
Lisinopril 3
Aspirin 2
Selamectin 2
Moxidectin 2
Hydrochlorothiazide 2
Fluoxetine Hcl 1
Bupropion 1
Levothyroxine Sodium 1
Emodepside + Praziquantel 1
Esomeprazole Magnesium 1
Zolpidem Tartrate 1
Clonazepam 1
Duloxetine 1
Darifenacin 1
Spinosad 1
Hormone Replacement Therapy 1

Chest discomfort NOS Reaction Insights

51 reports name Chest discomfort NOS; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 1263.

By species: Human (44 reports), Dog (5 reports), Horse (2 reports). By breed: Unknown (44), Pit Bull (2), Spaniel - Springer English (1).

Most co-reported drugs: Tilmicosin (10 reports), Milbemycin Oxime + Spinosad (7 reports), Tilmicosin Phosphate (5 reports), Nitenpyram (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.