Reaction profile

The FDA adverse-event record for oral haemorrhage

55 FDA adverse-event reports reference oral haemorrhage (VeDDRA 296). See the species, breeds, and drugs most associated with it below.

55
reports citing this reaction
52.7%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
55
Total Reports
29
Deaths
52.7%
Death Rate

Species Most Affected

Dog 42
Cat 10
Horse 1
Marsupial 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 7
Retriever - Labrador 6
Chihuahua 3
Shih Tzu 3
Retriever - Golden 3
Bulldog 2
Boxer (German Boxer) 2
Spaniel (unspecified) 2
Dog (other) 1
Quarter Horse 1

Associated Drugs

Carprofen 13
Cefovecin 7
Maropitant Citrate 7
Tramadol 5
Oclacitinib Maleate 5
Enrofloxacin 4
Propofol 4
Moxidectin 4
Selamectin 3
Doxycycline 3
Dexmedetomidine Hydrochloride 3
Milbemycin Oxime + Spinosad 3
Cefpodoxime Proxetil 2
Famotidine 2
Clindamycin 2
Atipamezole Hydrochloride 2
Hydromorphone Hcl 2
Isoflurane 2
Spinosad 2
Sucralfate 2

Oral haemorrhage Reaction Insights

55 reports name Oral haemorrhage; 29 recorded a death outcome (52.7% of reported events, not a population-level mortality rate). VeDDRA code: 296.

By species: Dog (42 reports), Cat (10 reports), Horse (1 reports). By breed: Domestic Shorthair (7), Retriever - Labrador (6), Chihuahua (3).

Most co-reported drugs: Carprofen (13 reports), Cefovecin (7 reports), Maropitant Citrate (7 reports), Tramadol (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.