Reaction profile

The FDA adverse-event record for monocytopenia

179 FDA adverse-event reports reference monocytopenia (VeDDRA 2860). See the species, breeds, and drugs most associated with it below.

179
reports citing this reaction
14.0%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
179
Total Reports
25
Deaths
14.0%
Death Rate

Species Most Affected

Dog 150
Cat 28
Horse 1

Breeds Most Affected

Domestic Shorthair 19
Retriever - Labrador 15
Crossbred Canine/dog 12
Chihuahua 8
Retriever - Golden 8
Shepherd Dog - Australian 8
Shih Tzu 7
Terrier (unspecified) 6
Bulldog - French 5
Pit Bull 5

Associated Drugs

Oclacitinib Maleate 59
Gabapentin 19
Ilunocitinib 17
Bedinvetmab 13
Carprofen 11
Enrofloxacin 11
Metronidazole 10
Maropitant Citrate 10
Milbemycin Oxime + Praziquantel 9
Cefovecin 9
Afoxolaner 8
Fluralaner 13.64% 12-Week Chew 7
Fenbendazol Granules 7
Ivermectin + Pyrantel As Pamoate Salt 6
Verdinexor 6
Moxidectin 6
Cefpodoxime 6
Anti-Il31 Mab Mcs Lot #1283563 5
Prednisone 5
Butorphanol 5

Monocytopenia Reaction Insights

179 reports name Monocytopenia; 25 recorded a death outcome (14.0% of reported events, not a population-level mortality rate). VeDDRA code: 2860.

By species: Dog (150 reports), Cat (28 reports), Horse (1 reports). By breed: Domestic Shorthair (19), Retriever - Labrador (15), Crossbred Canine/dog (12).

Most co-reported drugs: Oclacitinib Maleate (59 reports), Gabapentin (19 reports), Ilunocitinib (17 reports), Bedinvetmab (13 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.