FDA CVM rankings
Which breeds appear most in the FDA adverse-event record?
Breeds ranked by the total number of adverse-event reports filed with the FDA. Volume tracks how common a breed is and how actively its owners and vets report, a popular breed leads because there are simply more of them, not because it faces unusual risk.
- 90,806
- Retriever - Labrador - #1
- 506
- breeds tracked
- 1,048,915
- reports across all breeds
- Top 100
- shown below
Data updated June 2026
The verdict
Retriever - Labrador leads the FDA record with 90,806 reports, ahead of Crossbred Canine/dog (68,210) - both reflecting how many of these animals are kept and treated, not higher danger.
- 90,806
- Retriever - Labrador - most reported
- 68,210
- Crossbred Canine/dog - second
- 3.6%
- Retriever - Labrador death-coded share
Report volume is a popularity-and-reporting signal. To compare actual outcome severity, see the death-coded-share ranking instead.
According to the U.S. Food and Drug Administration's Center for Veterinary Medicine, more than 1,048,915 animal-drug adverse-event reports across 506 breeds had been filed as of the March 2026 data release, drawn from the openFDA Animal & Veterinary Adverse Event database. This ranking orders breeds by the total number of reports filed; the Labrador Retriever leads chiefly because it is among the most common dogs in the United States. See our methodology for how each figure is computed and refreshed.
How to read this: Higher report counts usually reflect breed popularity and product-usage volume, not higher health risk. Common breeds naturally accumulate more reports because more of their animals are treated and more owners and veterinarians file.
Top 12 breeds by report volume
FDA CVM Animal Adverse Event database, total reports filed
| # | Breed | Species | Reports | Deaths | Death-coded share | Avg Age |
|---|---|---|---|---|---|---|
| 1 | Retriever - Labrador | Dog | 90,806 | 3,311 | 3.6% | 5.2 yr |
| 2 | Crossbred Canine/dog | Dog | 68,210 | 2,161 | 3.2% | 5.3 yr |
| 3 | Domestic Shorthair | Cat | 61,410 | 4,445 | 7.2% | 7.0 yr |
| 4 | Dog (unknown) | Dog | 47,381 | 4,140 | 8.7% | 5.8 yr |
| 5 | Retriever - Golden | Dog | 34,475 | 1,286 | 3.7% | 4.6 yr |
| 6 | Shepherd Dog - German | Dog | 31,142 | 1,347 | 4.3% | 4.5 yr |
| 7 | Chihuahua | Dog | 30,657 | 1,284 | 4.2% | 5.8 yr |
| 8 | Terrier - Yorkshire | Dog | 24,408 | 904 | 3.7% | 5.7 yr |
| 9 | Shih Tzu | Dog | 23,826 | 842 | 3.5% | 6.0 yr |
| 10 | Boxer (German Boxer) | Dog | 19,011 | 836 | 4.4% | 4.5 yr |
| 11 | Beagle | Dog | 17,507 | 635 | 3.6% | 5.7 yr |
| 12 | Pit Bull | Dog | 17,328 | 540 | 3.1% | 4.0 yr |
| 13 | Shepherd Dog - Australian | Dog | 15,583 | 574 | 3.7% | 4.5 yr |
| 14 | Maltese | Dog | 13,674 | 443 | 3.2% | 5.6 yr |
| 15 | Terrier (unspecified) | Dog | 13,509 | 411 | 3.0% | 5.8 yr |
| 16 | Dachshund (unspecified) | Dog | 13,165 | 599 | 4.5% | 6.1 yr |
| 17 | Cat (unknown) | Cat | 12,555 | 1,163 | 9.3% | 6.8 yr |
| 18 | Terrier - Jack Russell | Dog | 10,210 | 375 | 3.7% | 6.8 yr |
| 19 | Collie - Border | Dog | 9,801 | 419 | 4.3% | 5.8 yr |
| 20 | Siberian Husky | Dog | 9,399 | 418 | 4.4% | 4.8 yr |
| 21 | Domestic Longhair | Cat | 9,078 | 630 | 6.9% | 7.5 yr |
| 22 | Pug | Dog | 9,020 | 461 | 5.1% | 6.0 yr |
| 23 | Spitz - German Pomeranian | Dog | 8,853 | 439 | 5.0% | 5.9 yr |
| 24 | Terrier - Bull - American Pit | Dog | 8,232 | 374 | 4.5% | 4.8 yr |
| 25 | Domestic (unspecified) | Cat | 7,559 | 1,012 | 13.4% | 6.5 yr |
| 26 | Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) | Dog | 7,541 | 268 | 3.6% | 4.8 yr |
| 27 | Spaniel - Cocker American | Dog | 7,534 | 300 | 4.0% | 6.1 yr |
| 28 | Terrier - Boston | Dog | 7,526 | 345 | 4.6% | 5.7 yr |
| 29 | Schnauzer - Miniature | Dog | 7,307 | 320 | 4.4% | 6.3 yr |
| 30 | Bulldog | Dog | 7,270 | 346 | 4.8% | 3.9 yr |
| 31 | Poodle (unspecified) | Dog | 7,250 | 254 | 3.5% | 5.5 yr |
| 32 | Bichon Frise | Dog | 6,966 | 267 | 3.8% | 7.1 yr |
| 33 | Bulldog - French | Dog | 6,836 | 301 | 4.4% | 3.4 yr |
| 34 | Rottweiler | Dog | 6,412 | 521 | 8.1% | 4.5 yr |
| 35 | Domestic Mediumhair | Cat | 6,057 | 460 | 7.6% | 6.7 yr |
| 36 | Dog (other) | Dog | 5,792 | 238 | 4.1% | 5.0 yr |
| 37 | Spaniel - King Charles Cavalier | Dog | 5,775 | 248 | 4.3% | 4.9 yr |
| 38 | Poodle - Miniature | Dog | 5,328 | 188 | 3.5% | 6.5 yr |
| 39 | Schnauzer (unspecified) | Dog | 5,279 | 215 | 4.1% | 6.2 yr |
| 40 | Mixed (Dog) | Dog | 5,264 | 302 | 5.7% | 5.4 yr |
| 41 | Hound (unspecified) | Dog | 4,645 | 107 | 2.3% | 4.1 yr |
| 42 | Cat (other) | Cat | 4,619 | 448 | 9.7% | 7.5 yr |
| 43 | Doberman Pinscher | Dog | 4,495 | 256 | 5.7% | 4.5 yr |
| 44 | Poodle - Standard | Dog | 4,455 | 140 | 3.1% | 4.8 yr |
| 45 | Great Pyrenees | Dog | 4,292 | 164 | 3.8% | 3.8 yr |
| 46 | Terrier - West Highland White | Dog | 4,266 | 211 | 4.9% | 7.4 yr |
| 47 | Deutsche Dogge, Great Dane | Dog | 4,227 | 255 | 6.0% | 3.5 yr |
| 48 | Dachshund - Miniature | Dog | 4,095 | 190 | 4.6% | 6.4 yr |
| 49 | Poodle - Toy | Dog | 4,084 | 164 | 4.0% | 6.2 yr |
| 50 | Sheepdog - Shetland | Dog | 4,080 | 271 | 6.6% | 6.8 yr |
| 51 | Hound - Basset | Dog | 3,859 | 153 | 4.0% | 5.5 yr |
| 52 | Havanese | Dog | 3,845 | 80 | 2.1% | 4.9 yr |
| 53 | Pointing Dog - German Short-haired | Dog | 3,752 | 125 | 3.3% | 5.0 yr |
| 54 | Pinscher - Miniature | Dog | 3,700 | 189 | 5.1% | 6.8 yr |
| 55 | Greyhound | Dog | 3,648 | 136 | 3.7% | 5.4 yr |
| 56 | Retriever (unspecified) | Dog | 3,439 | 65 | 1.9% | 4.4 yr |
| 57 | Lhasa Apso | Dog | 3,154 | 114 | 3.6% | 7.4 yr |
| 58 | Holstein-Friesian also known as Holstein | Cattle | 3,106 | 1,207 | 38.9% | 1.7 yr |
| 59 | Collie (unspecified) | Dog | 3,080 | 147 | 4.8% | 5.8 yr |
| 60 | Spaniel (unspecified) | Dog | 3,074 | 150 | 4.9% | 7.0 yr |
| 61 | Terrier - Rat | Dog | 3,013 | 131 | 4.3% | 6.7 yr |
| 62 | Cattle (other) | Cattle | 2,996 | 1,462 | 48.8% | 1.2 yr |
| 63 | Mastiff | Dog | 2,952 | 182 | 6.2% | 3.4 yr |
| 64 | Siamese | Cat | 2,946 | 244 | 8.3% | 7.4 yr |
| 65 | Mountain Dog - Bernese | Dog | 2,817 | 126 | 4.5% | 2.8 yr |
| 66 | Corgi (unspecified) | Dog | 2,744 | 118 | 4.3% | 5.3 yr |
| 67 | Shepherd (unspecified) | Dog | 2,725 | 119 | 4.4% | 5.5 yr |
| 68 | Terrier - Bull - Staffordshire | Dog | 2,607 | 116 | 4.4% | 5.0 yr |
| 69 | Mixed (Cattle) | Cattle | 2,581 | 1,224 | 47.4% | 1.1 yr |
| 70 | Pekingese | Dog | 2,525 | 100 | 4.0% | 7.0 yr |
| 71 | Weimaraner | Dog | 2,480 | 113 | 4.6% | 5.5 yr |
| 72 | Cattle (unknown) | Cattle | 2,424 | 934 | 38.5% | 1.2 yr |
| 73 | Bulldog - American | Dog | 2,409 | 119 | 4.9% | 4.3 yr |
| 74 | Quarter Horse | Horse | 2,403 | 273 | 11.4% | 12.7 yr |
| 75 | Catahoula Leopard Dog | Dog | 2,316 | 53 | 2.3% | 4.0 yr |
| 76 | Horse (unknown) | Horse | 2,290 | 229 | 10.0% | 13.8 yr |
| 77 | Maine Coon | Cat | 2,283 | 170 | 7.4% | 7.1 yr |
| 78 | Spaniel - Springer English | Dog | 2,187 | 85 | 3.9% | 6.0 yr |
| 79 | Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) | Dog | 2,087 | 91 | 4.4% | 6.7 yr |
| 80 | Chow Chow | Dog | 2,029 | 130 | 6.4% | 7.4 yr |
| 81 | Terrier - Cairn | Dog | 1,928 | 90 | 4.7% | 7.5 yr |
| 82 | Brittany | Dog | 1,837 | 49 | 2.7% | 6.0 yr |
| 83 | Shepherd Dog - Belgian Malinois | Dog | 1,623 | 48 | 3.0% | 4.4 yr |
| 84 | Shiba Inu | Dog | 1,622 | 40 | 2.5% | 5.4 yr |
| 85 | Terrier - Irish Soft-coated Wheaten | Dog | 1,617 | 52 | 3.2% | 6.0 yr |
| 86 | Aberdeen Angus | Cattle | 1,610 | 561 | 34.8% | 1.3 yr |
| 87 | Corgi - Welsh Pembroke | Dog | 1,555 | 65 | 4.2% | 5.2 yr |
| 88 | Pointer (unspecified) | Dog | 1,533 | 42 | 2.7% | 4.9 yr |
| 89 | Pointing Dog - Hungarian Short-haired (Vizsla) | Dog | 1,468 | 58 | 4.0% | 4.7 yr |
| 90 | Terrier - Scottish | Dog | 1,461 | 85 | 5.8% | 6.6 yr |
| 91 | Crossbred Bovine/Cattle | Cattle | 1,357 | 674 | 49.7% | 1.1 yr |
| 92 | American Pit Bull Terrier | Dog | 1,326 | 91 | 6.9% | 5.5 yr |
| 93 | Dalmatian | Dog | 1,321 | 61 | 4.6% | 5.7 yr |
| 94 | Ridgeback - Rhodesian | Dog | 1,291 | 67 | 5.2% | 5.1 yr |
| 95 | Shepherd Dog (unspecified) | Dog | 1,271 | 41 | 3.2% | 4.5 yr |
| 96 | Newfoundland | Dog | 1,261 | 91 | 7.2% | 4.8 yr |
| 97 | Shar Pei | Dog | 1,258 | 95 | 7.6% | 5.5 yr |
| 98 | Saint Bernard Dog | Dog | 1,253 | 98 | 7.8% | 4.4 yr |
| 99 | Spaniel - Cocker English | Dog | 1,243 | 31 | 2.5% | 5.9 yr |
| 100 | Coonhound (unspecified) | Dog | 1,210 | 36 | 3.0% | 4.7 yr |