Total Reports
2,087
FDA CVM filings
Dog /
FDA CVM · 2025 release 2,087 reports on file
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) - FDA Adverse Event Profile
Adverse-event records for Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) ranks #79 by report volume among dog breeds - 91 of 2,087 reports (4.4%) recorded a death outcome.
- #79
- most-reported dog breed
- 4.4%
- death-coded report share
- 521
- Vomiting - top reaction
- 6.7 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
91
of 2,087 reports
Death Rate
4.4%
death-coded share
Avg Age at Report
6.7 yr
5.0 kg avg weight
Death-Coded Outcome Share
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) death-coded reports 4.4%
Cross-breed median
4.4% of 2,087 papillon - spaniel - continental toy (with erect ears or with dropped ears (phaléne)) reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 5.0 kg (11.0 lbs)
Top Reported Reactions
Vomiting 521
Lethargy (see also Central nervous system depression in 'Neurological') 241
Emesis 201
Lack of efficacy (ectoparasite) - flea 196
Diarrhoea 190
Anorexia 108
Seizure NOS 107
Lack of efficacy - NOS 100
Behavioural disorder NOS 77
Pruritus 70
Other abnormal test result NOS 62
Decreased appetite 58
Lack of efficacy (endoparasite) - hookworm 54
Panting 53
Not eating 51
Most Referenced Drugs
Milbemycin Oxime + Spinosad 391
Spinosad 222
Afoxolaner 152
Ivermectin + Pyrantel As Pamoate Salt 136
Fluralaner Chew Tablets 113
Pyrantel Pamoate;Sarolaner 77
Selamectin 66
Imidacloprid + Moxidectin 60
Moxidectin 55
Oclacitinib Maleate 51
Fluralaner 13.64% 12-Week Chew 50
Milbemycin Oxime + Praziquantel 46
Maropitant Citrate 43
Sarolaner 42
Ivermectin, Pyrantel 37
Outcome Breakdown
Recovered/Normal
782 (41.1%)
Outcome Unknown
557 (29.3%)
Ongoing
385 (20.3%)
Recovered with Sequela
86 (4.5%)
Died
57 (3.0%)
Euthanized
34 (1.8%)
Gender Distribution
Female 1,025 (49.1%)
Male 1,012 (48.5%)
Unknown 48 (2.3%)
Mixed 2 (0.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 107 | |
| 2011 | 126 | |
| 2012 | 175 | |
| 2013 | 195 | |
| 2014 | 164 | |
| 2015 | 184 | |
| 2016 | 176 | |
| 2017 | 138 | |
| 2018 | 161 | |
| 2019 | 128 | |
| 2020 | 103 | |
| 2021 | 97 | |
| 2022 | 73 | |
| 2023 | 96 | |
| 2024 | 74 | |
| 2025 | 90 | |
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) Pet Health Insights
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) accounts for 2,087 FDA adverse event reports, ranking #79 by volume among dog breeds, with 91 reports (4.4%) coded as a death outcome. Mean age at report: 6.7 years, average weight 5.0 kg (11.0 lbs).
Top reported signs: Vomiting (521), Lethargy (see also Central nervous system depression in 'Neurological') (241), Emesis (201). Most-referenced drug: Milbemycin Oxime + Spinosad (391 reports), followed by Spinosad (222) and Afoxolaner (152).
Outcome coding on 1,901 status-recorded reports is dominated by Recovered/Normal (41.1%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne))? ▼
There are 2,087 adverse event reports involving Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) in the FDA database, with 91 reports involving death (4.4% death rate). Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) ranks #79 by report volume.
What are the most common adverse reactions reported for Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne))? ▼
The most commonly reported adverse reactions for Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) are Vomiting (521 reports), Lethargy (see also Central nervous system depression in 'Neurological') (241 reports), Emesis (201 reports), Lack of efficacy (ectoparasite) - flea (196 reports), Diarrhoea (190 reports).
What drugs are most frequently associated with Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) adverse events? ▼
The drugs most frequently referenced in Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) adverse event reports are Milbemycin Oxime + Spinosad (391 reports), Spinosad (222 reports), Afoxolaner (152 reports), Ivermectin + Pyrantel As Pamoate Salt (136 reports), Fluralaner Chew Tablets (113 reports).
What is the average age of Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) in adverse event reports? ▼
The average age of Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) at the time of adverse event reports is 6.7 years, with an average weight of 5.0 kg (11.0 lbs).
Does a high number of adverse event reports mean Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.