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Breed profile · FDA CVM July 2026 extract

Shepherd Dog (unspecified) adverse-event record

Adverse-event filings for Shepherd Dog (unspecified) (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#96 of 510
by report volume (all breeds)
1,313
FDA CVM reports on file
3.3%
death-coded share of reports
#215 of 275
by death-coded share (≥50 reports)

How the 1,313 reports break down

By recorded gender -- every report on file for Shepherd Dog (unspecified), no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 140 105 70 35 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Shepherd Dog (unspecified) drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Shepherd Dog (unspecified) ranks #96 of 510 by total reports (1,313) and #215 of 275 by death-coded share (3.3%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#96
This breed, reports of 510
#215
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Shepherd Dog (unspecified) has 1,313 reports now versus 1,295 in that prior snapshot: 18 more (1.4%).

Report change
+18
Death-coded reports
+2
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Shepherd Dog (unspecified) changes

Total Reports

1,313

High report volume

Deaths Reported

43

of 1,313 reports

Death-coded share of reports

3.3%

Lowest death-coded share

Avg Age at Report

4.6 yr

27.0 kg avg weight

Breed Safety Scorecard

A- (80/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate A-
3.3%

Share of reports coded as a fatality

Euthanasia rate A-
1.4%

Share of reports resulting in euthanasia

Full recovery rate B-
32.4%

Share of reports coded "Recovered/Normal"

5-year trend A
-34%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Shepherd Dog (unspecified) death-coded reports 3.3%
Cross-breed median

3.3% of 1,313 shepherd dog (unspecified) reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Shepherd Dog (unspecified)'s death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

3% 22nd percentile Higher share than 22% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Shepherd Dog (unspecified) 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 27.0 kg (59.5 lbs)

Top Reported Reactions

Lack of efficacy (endoparasite) - heartworm 256
Vomiting 202
Emesis 179
Lethargy (see also Central nervous system depression in 'Neurological') 90
Diarrhoea 69
INEFFECTIVE, HEARTWORM LARVAE 69
Lack of efficacy (endoparasite) - hookworm 67
Lack of efficacy - NOS 58
INEFFECTIVE, HOOKS 45
Lack of efficacy (ectoparasite) - tick NOS 40
Lack of efficacy (endoparasite) - roundworm NOS 40
Seizure NOS 36
Lack of efficacy (ectoparasite) - flea 36
Lack of efficacy (bacteria) - NOS 28
Other abnormal test result NOS 27

Most Referenced Drugs

Ivermectin + Pyrantel As Pamoate Salt 420
Milbemycin Oxime + Spinosad 387
Afoxolaner 186
Milbemycin Oxime + Praziquantel 130
Spinosad 71
Grapiprant 27
Melarsomine Dihydrochloride 24
Lotilaner 22
Milbemycin Oxime 18
Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet 17
Ivermectin 16
Fluralaner 13.64% 12-Week Chew 16
Carprofen 15
Recombitek Lyme - 2126.R0 15
Afoxolaner 150Mg / Moxidectin 720Mcg / Pyrantel 300Mg Chewable Tablet 15

Outcome Breakdown

Outcome Unknown
543 (41.3%)
Recovered/Normal
426 (32.4%)
Ongoing
186 (14.2%)
Recovered with Sequela
116 (8.8%)
Died
24 (1.8%)
Euthanized
19 (1.4%)

Gender Distribution

Female 718 (54.7%)
Male 573 (43.6%)
Unknown 18 (1.4%)
Mixed 4 (0.3%)

Reports by Year

Year Reports Trend
2010 1
2011 4
2012 54
2013 120
2014 87
2015 54
2016 70
2017 100
2018 127
2019 140
2020 126
2021 110
2022 84
2023 77
2024 72
2025 73
2026 14

Shepherd Dog (unspecified): low death-coded share in the FDA CVM extract

Signature read: 1,313 reports place Shepherd Dog (unspecified) in the upper third of breed filing volume (#96 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Shepherd Dog (unspecified) sits at #96 of 510 by report volume among all breeds and #80 of 298 among dog breeds, with 1,313 reports and 43 (3.3%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #215 of 275. Mean age at report: 4.6 years, average weight 27.0 kg (59.5 lbs).

Top reported signs: Lack of efficacy (endoparasite) - heartworm (256), Vomiting (202), Emesis (179). Most-referenced drug: Ivermectin + Pyrantel As Pamoate Salt (420 reports), followed by Milbemycin Oxime + Spinosad (387) and Afoxolaner (186).

Outcome coding on 1,314 status-recorded reports is dominated by Outcome Unknown (41.3%). Annual submissions ranged 1-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Spaniel - Cocker English
1,321 reports · 2.6% death-coded
Shar Pei
1,304 reports · 7.5% death-coded
Newfoundland
1,299 reports · 7.0% death-coded
Ridgeback - Rhodesian
1,331 reports · 5.2% death-coded
Saint Bernard Dog
1,292 reports · 7.7% death-coded
Dalmatian
1,356 reports · 4.6% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Shepherd Dog (unspecified) drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (3.3% death-coded here).

Oriental 3.1% · Cat Birman (Sacred Birman) 3.1% · Cat American Curl Shorthair 3.5% · Cat Oldenburg 2.8% · Horse

Similar average weight

Nearest other-species breeds by reported average weight (27.0 kg here).

Mixed (Sheep) 24.9 kg · Sheep Crossbred Caprine/goat 21.7 kg · Goat Fish (other) 32.4 kg · Fish Katahdin 32.4 kg · Sheep

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Shepherd Dog (unspecified)? ▼
There are 1,313 adverse event reports involving Shepherd Dog (unspecified) in the FDA database, of which 43 were death-coded (3.3% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Shepherd Dog (unspecified) ranks #96 of 510 by report volume among all breeds PlainBreed indexes (#80 of 298 among dog breeds).
Where does Shepherd Dog (unspecified) sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Shepherd Dog (unspecified) is #96 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #80 of 298. Among breeds with at least 50 reports, its death-coded share ranks #215 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Shepherd Dog (unspecified)? ▼
The most commonly reported adverse reactions for Shepherd Dog (unspecified) are Lack of efficacy (endoparasite) - heartworm (256 reports), Vomiting (202 reports), Emesis (179 reports), Lethargy (see also Central nervous system depression in 'Neurological') (90 reports), Diarrhoea (69 reports).
What drugs are most frequently associated with Shepherd Dog (unspecified) adverse events? ▼
The drugs most frequently referenced in Shepherd Dog (unspecified) adverse event reports are Ivermectin + Pyrantel As Pamoate Salt (420 reports), Milbemycin Oxime + Spinosad (387 reports), Afoxolaner (186 reports), Milbemycin Oxime + Praziquantel (130 reports), Spinosad (71 reports).
What is the average age of Shepherd Dog (unspecified) in adverse event reports? ▼
The average age of Shepherd Dog (unspecified) at the time of adverse event reports is 4.6 years, with an average weight of 27.0 kg (59.5 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Shepherd Dog (unspecified) (Dog), extract as of July 2026 extract. 1,313 reports · 43 death-coded (3.3% of reports, not a mortality rate) · #96 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →