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Breed profile · FDA CVM July 2026 extract

Catahoula Leopard Dog adverse-event record

Adverse-event filings for Catahoula Leopard Dog (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#75 of 510
by report volume (all breeds)
2,402
FDA CVM reports on file
2.2%
death-coded share of reports
#255 of 275
by death-coded share (≥50 reports)

How the 2,402 reports break down

By recorded gender -- every report on file for Catahoula Leopard Dog, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 208 156 104 52 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Catahoula Leopard Dog drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Catahoula Leopard Dog ranks #75 of 510 by total reports (2,402) and #255 of 275 by death-coded share (2.2%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#75
This breed, reports of 510
#255
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Catahoula Leopard Dog has 2,402 reports now versus 2,362 in that prior snapshot: 40 more (1.7%).

Report change
+40
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Catahoula Leopard Dog changes

Total Reports

2,402

High report volume

Deaths Reported

54

of 2,402 reports

Death-coded share of reports

2.2%

Lowest death-coded share

Avg Age at Report

4.0 yr

26.3 kg avg weight

Breed Safety Scorecard

B (73/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate A+
2.2%

Share of reports coded as a fatality

Euthanasia rate A+
1.0%

Share of reports resulting in euthanasia

Full recovery rate F
24.4%

Share of reports coded "Recovered/Normal"

5-year trend B+
-15%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Catahoula Leopard Dog death-coded reports 2.2%
Cross-breed median

2.2% of 2,402 catahoula leopard dog reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Catahoula Leopard Dog's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

2% 7th percentile Higher share than 7% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Catahoula Leopard Dog 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 26.3 kg (58.0 lbs)

Top Reported Reactions

Lack of efficacy (endoparasite) - heartworm 533
Vomiting 371
INEFFECTIVE, HEARTWORM LARVAE 264
Lack of efficacy (endoparasite) - hookworm 148
Lethargy (see also Central nervous system depression in 'Neurological') 144
Emesis 141
Lack of efficacy - NOS 136
Diarrhoea 121
Lack of efficacy (ectoparasite) - flea 82
Cardiac disorder NOS 72
Seizure NOS 66
INEFFECTIVE, HOOKS 62
Other abnormal test result NOS 47
Lack of efficacy (ectoparasite) - tick NOS 44
Digestive tract disorder NOS 43

Most Referenced Drugs

Milbemycin Oxime + Spinosad 513
Ivermectin + Pyrantel As Pamoate Salt 417
Moxidectin 245
Milbemycin Oxime + Praziquantel 194
Pyrantel Pamoate;Sarolaner 172
Afoxolaner 112
Fluralaner Chew Tablets 75
Spinosad 69
Melarsomine Dihydrochloride 65
Ivermectin 52
Lufenuron + Milbemycin Oxime 52
Oclacitinib Maleate 51
Bedinvetmab 50
Fluralaner 13.64% 12-Week Chew 49
Milbemycin Oxime 47

Outcome Breakdown

Outcome Unknown
822 (35.2%)
Ongoing
712 (30.5%)
Recovered/Normal
585 (25.1%)
Recovered with Sequela
159 (6.8%)
Died
31 (1.3%)
Euthanized
23 (1.0%)

Gender Distribution

Female 1,283 (53.4%)
Male 1,086 (45.2%)
Unknown 23 (1.0%)
Mixed 10 (0.4%)

Reports by Year

Year Reports Trend
2010 48
2011 51
2012 76
2013 124
2014 144
2015 148
2016 164
2017 173
2018 195
2019 208
2020 183
2021 193
2022 159
2023 157
2024 179
2025 165
2026 35

Catahoula Leopard Dog: low death-coded share in the FDA CVM extract

Signature read: Catahoula Leopard Dog's 2.2% death-coded share is in the lower third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Catahoula Leopard Dog sits at #75 of 510 by report volume among all breeds and #63 of 298 among dog breeds, with 2,402 reports and 54 (2.2%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #255 of 275. Mean age at report: 4.0 years, average weight 26.3 kg (58.0 lbs).

Top reported signs: Lack of efficacy (endoparasite) - heartworm (533), Vomiting (371), INEFFECTIVE, HEARTWORM LARVAE (264). Most-referenced drug: Milbemycin Oxime + Spinosad (513 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (417) and Moxidectin (245).

Outcome coding on 2,332 status-recorded reports is dominated by Outcome Unknown (35.2%). Annual submissions ranged 35-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Bulldog - American
2,514 reports · 5.1% death-coded
Spaniel - Springer English
2,268 reports · 4.0% death-coded
Weimaraner
2,538 reports · 4.5% death-coded
Pekingese
2,552 reports · 4.0% death-coded
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne))
2,120 reports · 4.5% death-coded
Chow Chow
2,065 reports · 6.4% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Catahoula Leopard Dog drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (2.2% death-coded here).

Hanovarian 2.2% · Horse Warmblood - Dutch 2.7% · Horse Oldenburg 2.8% · Horse Birman (Sacred Birman) 3.1% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (26.3 kg here).

Mixed (Sheep) 24.9 kg · Sheep Crossbred Caprine/goat 21.7 kg · Goat Pygmy 20.3 kg · Goat Fish (other) 32.4 kg · Fish

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Catahoula Leopard Dog? ▼
There are 2,402 adverse event reports involving Catahoula Leopard Dog in the FDA database, of which 54 were death-coded (2.2% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Catahoula Leopard Dog ranks #75 of 510 by report volume among all breeds PlainBreed indexes (#63 of 298 among dog breeds).
Where does Catahoula Leopard Dog sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Catahoula Leopard Dog is #75 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #63 of 298. Among breeds with at least 50 reports, its death-coded share ranks #255 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Catahoula Leopard Dog? ▼
The most commonly reported adverse reactions for Catahoula Leopard Dog are Lack of efficacy (endoparasite) - heartworm (533 reports), Vomiting (371 reports), INEFFECTIVE, HEARTWORM LARVAE (264 reports), Lack of efficacy (endoparasite) - hookworm (148 reports), Lethargy (see also Central nervous system depression in 'Neurological') (144 reports).
What drugs are most frequently associated with Catahoula Leopard Dog adverse events? ▼
The drugs most frequently referenced in Catahoula Leopard Dog adverse event reports are Milbemycin Oxime + Spinosad (513 reports), Ivermectin + Pyrantel As Pamoate Salt (417 reports), Moxidectin (245 reports), Milbemycin Oxime + Praziquantel (194 reports), Pyrantel Pamoate;Sarolaner (172 reports).
What is the average age of Catahoula Leopard Dog in adverse event reports? ▼
The average age of Catahoula Leopard Dog at the time of adverse event reports is 4.0 years, with an average weight of 26.3 kg (58.0 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Catahoula Leopard Dog (Dog), extract as of July 2026 extract. 2,402 reports · 54 death-coded (2.2% of reports, not a mortality rate) · #75 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →