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Breed profile · FDA CVM July 2026 extract

Mixed (Cattle) adverse-event record

Adverse-event filings for Mixed (Cattle) (Cattle) in the FDA Center for Veterinary Medicine openFDA extract. Browse cattle breeds, reactions, and outcomes below.

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#69 of 510
by report volume (all breeds)
2,695
FDA CVM reports on file
48.3%
death-coded share of reports
#12 of 275
by death-coded share (≥50 reports)

How the 2,695 reports break down

By recorded gender -- every report on file for Mixed (Cattle), no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 291 218.25 145.5 72.75 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Mixed (Cattle) drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Mixed (Cattle) ranks #69 of 510 by total reports (2,695) and #12 of 275 by death-coded share (48.3%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#69
This breed, reports of 510
#12
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Mixed (Cattle) has 2,695 reports now versus 2,663 in that prior snapshot: 32 more (1.2%).

Report change
+32
Death-coded reports
+19
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Mixed (Cattle) changes

Total Reports

2,695

High report volume

Deaths Reported

1,303

of 2,695 reports

Death-coded share of reports

48.3%

Highest death-coded share

Avg Age at Report

1.1 yr

254.0 kg avg weight

Breed Safety Scorecard

F (19/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate F
48.3%

Share of reports coded as a fatality

Euthanasia rate F
2.6%

Share of reports resulting in euthanasia

Full recovery rate F
11.1%

Share of reports coded "Recovered/Normal"

5-year trend C-
+6%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Mixed (Cattle) death-coded reports 48.3%
Cross-breed median

48.3% of 2,695 mixed (cattle) reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Mixed (Cattle)'s death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

48% 96th percentile Higher share than 96% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). Below this entry. 20%–25%: 2 indexed breeds (1%). Below this entry. 25%–30%: 3 indexed breeds (1%). Below this entry. 30%–35%: 4 indexed breeds (1%). Below this entry. 35%–40%: 5 indexed breeds (2%). Below this entry. 40%–45%: 6 indexed breeds (2%). Below this entry. 45%–50%: 3 indexed breeds (1%). This entry sits in this band. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Mixed (Cattle) 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 254.0 kg (560.1 lbs)

Top Reported Reactions

Death 1,043
Lack of efficacy - NOS 915
Lack of efficacy (lice) 247
Lack of efficacy (bacteria) - NOS 173
Necropsy performed 159
Lack of efficacy (ectoparasite) - lice 126
Unrelated death 87
Increased sexual interest 73
INEFFECTIVE, ANTIBIOTIC 68
Death by euthanasia 60
Injection site swelling 59
Sudden death 54
Anaphylactic-type reaction 48
INEFFECTIVE, ESTRUS SUPPRESSIO 45
Unexplained death 41

Most Referenced Drugs

Tulathromycin 736
Doramectin 622
Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus 386
Ceftiofur Crystalline Free Acid 350
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra 221
Bovine Viral Diarrhea Virus, Type 2, Strain 53637, Lot Bvd2Mlv-D;Bovine Viral Di 219
Dinoprost Tromethamine 134
Trenbolone Acetate;Estradiol Benzoate 134
Ketoprofen;Tulathromycin 132
Melengestrol Acetate 121
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 115
Monensin Sodium 110
Clostridium Novyi, 8296;Clostridium Perfringens Type C, Pc8 108
Progesterone 101
Albendazole 87

Outcome Breakdown

Outcome Unknown
1,791 (48.5%)
Died
1,269 (34.4%)
Recovered/Normal
298 (8.1%)
Ongoing
222 (6.0%)
Euthanized
69 (1.9%)
Recovered with Sequela
41 (1.1%)

Gender Distribution

Mixed 880 (32.7%)
Female 835 (31.0%)
Male 608 (22.6%)
Unknown 372 (13.8%)

Reports by Year

Year Reports Trend
2010 25
2011 24
2012 16
2013 32
2014 29
2015 118
2016 240
2017 347
2018 278
2019 291
2020 247
2021 186
2022 172
2023 232
2024 236
2025 198
2026 24

Mixed (Cattle): high death-coded share in the FDA CVM extract

Signature read: Mixed (Cattle)'s 48.3% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Mixed (Cattle) sits at #69 of 510 by report volume among all breeds and #3 of 30 among cattle breeds, with 2,695 reports and 1,303 (48.3%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #12 of 275. Mean age at report: 1.1 years, average weight 254.0 kg (560.1 lbs).

Top reported signs: Death (1,043), Lack of efficacy - NOS (915), Lack of efficacy (lice) (247). Most-referenced drug: Tulathromycin (736 reports), followed by Doramectin (622) and Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus (386).

Outcome coding on 3,690 status-recorded reports is dominated by Outcome Unknown (48.5%). Annual submissions ranged 16-2,026 across 17 years on file.

Cattle Breeds With a Similar Report Volume

Showing 6 of 29 cattle breeds in our dataset, ranked by closest report volume.

Cattle (unknown)
2,461 reports · 39.0% death-coded
Cattle (other)
3,054 reports · 49.0% death-coded
Holstein-Friesian also known as Holstein
3,156 reports · 38.9% death-coded
Aberdeen Angus
1,639 reports · 35.1% death-coded
Crossbred Bovine/Cattle
1,379 reports · 50.2% death-coded
Jersey
333 reports · 37.8% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Mixed (Cattle) drawn from openFDA outside the Cattle family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (48.3% death-coded here).

Sheep (unknown) 51.0% · Sheep Pig (unknown) 51.8% · Pig Crossbred Porcine/Pig 44.2% · Pig Pig (other) 52.9% · Pig

Similar average weight

Nearest other-species breeds by reported average weight (254.0 kg here).

Clydesdale 269.0 kg · Horse Shire 238.1 kg · Horse Hackney 271.1 kg · Horse Pony (unspecified) 271.4 kg · Horse

What to do with this cattle

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Mixed (Cattle)? ▼
There are 2,695 adverse event reports involving Mixed (Cattle) in the FDA database, of which 1,303 were death-coded (48.3% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Mixed (Cattle) ranks #69 of 510 by report volume among all breeds PlainBreed indexes (#3 of 30 among cattle breeds).
Where does Mixed (Cattle) sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Mixed (Cattle) is #69 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Cattle, it is #3 of 30. Among breeds with at least 50 reports, its death-coded share ranks #12 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Mixed (Cattle)? ▼
The most commonly reported adverse reactions for Mixed (Cattle) are Death (1,043 reports), Lack of efficacy - NOS (915 reports), Lack of efficacy (lice) (247 reports), Lack of efficacy (bacteria) - NOS (173 reports), Necropsy performed (159 reports).
What drugs are most frequently associated with Mixed (Cattle) adverse events? ▼
The drugs most frequently referenced in Mixed (Cattle) adverse event reports are Tulathromycin (736 reports), Doramectin (622 reports), Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus (386 reports), Ceftiofur Crystalline Free Acid (350 reports), Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra (221 reports).
What is the average age of Mixed (Cattle) in adverse event reports? ▼
The average age of Mixed (Cattle) at the time of adverse event reports is 1.1 years, with an average weight of 254.0 kg (560.1 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Mixed (Cattle) (Cattle), extract as of July 2026 extract. 2,695 reports · 1,303 death-coded (48.3% of reports, not a mortality rate) · #69 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →