Total Reports
2,581
FDA CVM filings
Cattle /
FDA CVM · 2025 release 2,581 reports on file
Mixed (Cattle) - FDA Adverse Event Profile
Adverse-event records for Mixed (Cattle) (Cattle) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Mixed (Cattle)'s FDA record: #69 most-reported cattle breed, 2,581 total reports, 47.4% death-coded (1,224 reports).
- #69
- most-reported cattle breed
- 47.4%
- death-coded report share
- 972
- Death - top reaction
- 1.1 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
1,224
of 2,581 reports
Death Rate
47.4%
death-coded share
Avg Age at Report
1.1 yr
254.8 kg avg weight
Death-Coded Outcome Share
Mixed (Cattle) death-coded reports 47.4%
Cross-breed median
47.4% of 2,581 mixed (cattle) reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 254.8 kg (561.8 lbs)
Top Reported Reactions
Death 972
Lack of efficacy - NOS 863
Lack of efficacy (lice) 247
Lack of efficacy (bacteria) - NOS 169
Lack of efficacy (ectoparasite) - lice 118
Necropsy performed 118
Unrelated death 87
Increased sexual interest 70
INEFFECTIVE, ANTIBIOTIC 68
Death by euthanasia 57
Injection site swelling 56
Sudden death 54
Anaphylactic-type reaction 48
INEFFECTIVE, ESTRUS SUPPRESSIO 45
CULTURE/TITER DATA ABNORMAL 39
Most Referenced Drugs
Tulathromycin 699
Doramectin 609
Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus 361
Ceftiofur Crystalline Free Acid 334
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra 221
Bovine Viral Diarrhea Virus, Type 2, Strain 53637, Lot Bvd2Mlv-D;Bovine Viral Di 219
Dinoprost Tromethamine 133
Trenbolone Acetate;Estradiol Benzoate 129
Melengestrol Acetate 121
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 115
Ketoprofen;Tulathromycin 115
Clostridium Novyi, 8296;Clostridium Perfringens Type C, Pc8 108
Monensin Sodium 106
Progesterone 97
Albendazole 87
Outcome Breakdown
Outcome Unknown
1,735 (49.5%)
Died
1,193 (34.0%)
Recovered/Normal
278 (7.9%)
Ongoing
195 (5.6%)
Euthanized
66 (1.9%)
Recovered with Sequela
40 (1.1%)
Gender Distribution
Mixed 846 (32.8%)
Female 801 (31.0%)
Male 587 (22.7%)
Unknown 347 (13.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 25 | |
| 2011 | 24 | |
| 2012 | 16 | |
| 2013 | 32 | |
| 2014 | 29 | |
| 2015 | 118 | |
| 2016 | 240 | |
| 2017 | 347 | |
| 2018 | 278 | |
| 2019 | 291 | |
| 2020 | 247 | |
| 2021 | 186 | |
| 2022 | 172 | |
| 2023 | 231 | |
| 2024 | 235 | |
| 2025 | 110 | |
Mixed (Cattle) Pet Health Insights
Mixed (Cattle) accounts for 2,581 FDA adverse event reports, ranking #69 by volume among cattle breeds, with 1,224 reports (47.4%) coded as a death outcome. Mean age at report: 1.1 years, average weight 254.8 kg (561.8 lbs).
Top reported signs: Death (972), Lack of efficacy - NOS (863), Lack of efficacy (lice) (247). Most-referenced drug: Tulathromycin (699 reports), followed by Doramectin (609) and Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus (361).
Outcome coding on 3,507 status-recorded reports is dominated by Outcome Unknown (49.5%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Cattle Breeds With a Similar Report Volume
Cattle (unknown)
2,424 reports · 38.5% death rate
Cattle (other)
2,996 reports · 48.8% death rate
Holstein-Friesian also known as Holstein
3,106 reports · 38.9% death rate
Aberdeen Angus
1,610 reports · 34.8% death rate
Crossbred Bovine/Cattle
1,357 reports · 49.7% death rate
Jersey
325 reports · 37.8% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Mixed (Cattle)? ▼
There are 2,581 adverse event reports involving Mixed (Cattle) in the FDA database, with 1,224 reports involving death (47.4% death rate). Mixed (Cattle) ranks #69 by report volume.
What are the most common adverse reactions reported for Mixed (Cattle)? ▼
The most commonly reported adverse reactions for Mixed (Cattle) are Death (972 reports), Lack of efficacy - NOS (863 reports), Lack of efficacy (lice) (247 reports), Lack of efficacy (bacteria) - NOS (169 reports), Lack of efficacy (ectoparasite) - lice (118 reports).
What drugs are most frequently associated with Mixed (Cattle) adverse events? ▼
The drugs most frequently referenced in Mixed (Cattle) adverse event reports are Tulathromycin (699 reports), Doramectin (609 reports), Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus (361 reports), Ceftiofur Crystalline Free Acid (334 reports), Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra (221 reports).
What is the average age of Mixed (Cattle) in adverse event reports? ▼
The average age of Mixed (Cattle) at the time of adverse event reports is 1.1 years, with an average weight of 254.8 kg (561.8 lbs).
Does a high number of adverse event reports mean Mixed (Cattle) is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Mixed (Cattle) safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.