Cattle /

Mixed (Cattle)

2,581 adverse event reports submitted to the FDA

Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cattle.
2,581
Total Reports
1,224
Deaths Reported
4740.0%
Death Rate
1.1 yr
Avg Age at Report
Average weight at time of report: 254.8 kg (561.8 lbs)

Top Reported Reactions

Death 972
Lack of efficacy - NOS 863
Lack of efficacy (lice) 247
Lack of efficacy (bacteria) - NOS 169
Lack of efficacy (ectoparasite) - lice 118
Necropsy performed 118
Unrelated death 87
Increased sexual interest 70
INEFFECTIVE, ANTIBIOTIC 68
Death by euthanasia 57
Injection site swelling 56
Sudden death 54
Anaphylactic-type reaction 48
INEFFECTIVE, ESTRUS SUPPRESSIO 45
CULTURE/TITER DATA ABNORMAL 39

Most Referenced Drugs

Tulathromycin 699
Doramectin 609
Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus 361
Ceftiofur Crystalline Free Acid 334
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra 221
Bovine Viral Diarrhea Virus, Type 2, Strain 53637, Lot Bvd2Mlv-D;Bovine Viral Di 219
Dinoprost Tromethamine 133
Trenbolone Acetate;Estradiol Benzoate 129
Melengestrol Acetate 121
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 115
Ketoprofen;Tulathromycin 115
Clostridium Novyi, 8296;Clostridium Perfringens Type C, Pc8 108
Monensin Sodium 106
Progesterone 97
Albendazole 87

Outcome Breakdown

Outcome Unknown
1,735 (49.5%)
Died
1,193 (34.0%)
Recovered/Normal
278 (7.9%)
Ongoing
195 (5.6%)
Euthanized
66 (1.9%)
Recovered with Sequela
40 (1.1%)

Gender Distribution

Mixed 846 (32.8%)
Female 801 (31.0%)
Male 587 (22.7%)
Unknown 347 (13.4%)

Reports by Year

Year Reports Trend
2010 25
2011 24
2012 16
2013 32
2014 29
2015 118
2016 240
2017 347
2018 278
2019 291
2020 247
2021 186
2022 172
2023 231
2024 235
2025 110

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #69 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.