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2026 FDA CVM data 10,210 reports on file official source

Terrier - Jack Russell — FDA Adverse Event Profile

Adverse-event records and label data for Terrier - Jack Russell (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 680 510 340 170 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Terrier - Jack Russell drawn from FDA CVM filings.

Terrier - Jack Russell (Dog) has 10,210 FDA adverse event reports on record, with 375 deaths reported (370.0% death rate) — ranking #18 by report volume. The most frequently reported reaction is Vomiting (2,152 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 6.8 years.

Total Reports

10,210

FDA CVM filings

Deaths Reported

375

of 10,210 reports

Death Rate

370.0%

death-coded share

Avg Age at Report

6.8 yr

8.6 kg avg weight

Death-Coded Outcome Share

Terrier - Jack Russell death-coded reports 100.0%
Database median

370.0% of 10,210 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 8.6 kg (19.0 lbs)

Top Reported Reactions

Vomiting 2,152
Lethargy (see also Central nervous system depression in 'Neurological') 1,033
Emesis 1,013
Lack of efficacy (ectoparasite) - flea 957
Diarrhoea 676
Lack of efficacy - NOS 603
INEFFECTIVE, HEARTWORM LARVAE 478
Lack of efficacy (endoparasite) - hookworm 439
Seizure NOS 435
Lack of efficacy (endoparasite) - heartworm 432
Anorexia 350
Pruritus 282
Behavioural disorder NOS 280
Digestive tract disorder NOS 261
Shaking 252

Most Referenced Drugs

Milbemycin Oxime + Spinosad 2,175
Spinosad 1,043
Ivermectin + Pyrantel As Pamoate Salt 872
Afoxolaner 641
Moxidectin 488
Fluralaner Chew Tablets 442
Oclacitinib Maleate 424
Pyrantel Pamoate;Sarolaner 384
Trilostane 312
Milbemycin Oxime + Praziquantel 264
Fluralaner 13.64% 12-Week Chew 221
Nitenpyram 201
Sarolaner 198
Carprofen 195
Selamectin 154

Outcome Breakdown

Recovered/Normal
3,261 (35.1%)
Outcome Unknown
3,155 (34.0%)
Ongoing
2,081 (22.4%)
Recovered with Sequela
407 (4.4%)
Died
194 (2.1%)
Euthanized
181 (2.0%)

Gender Distribution

Male 5,123 (50.2%)
Female 4,856 (47.6%)
Unknown 206 (2.0%)
Mixed 25 (0.2%)

Reports by Year

Year Reports Trend
2010 505
2011 675
2012 854
2013 839
2014 817
2015 913
2016 864
2017 780
2018 680
2019 627
2020 575
2021 482
2022 415
2023 448
2024 449
2025 287
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Terrier - Jack Russell sits in the registered size-class taxonomy. Average reported weight: 8.6 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Terrier - Jack Russell Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Terrier - Jack Russell accounts for 10,210 submitted reports and currently ranks #18 by report volume within the dog population. Of those reports, 375 involved a death outcome — a 370.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 6.8 years, with an average recorded body weight of 8.6 kg (19.0 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Terrier - Jack Russell are Vomiting (2,152 reports), Lethargy (see also Central nervous system depression in 'Neurological') (1,033 reports), Emesis (1,013 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 2,175 reports and is the single most-referenced drug, followed by Spinosad (1,043) and Ivermectin + Pyrantel As Pamoate Salt (872). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 9,279 reports with a recorded status is dominated by Recovered/Normal (35.1% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Terrier - Jack Russell Adverse Event Data

With 10,210 adverse event reports, Terrier - Jack Russell has one of the larger report volumes in the FDA database. This typically reflects breed popularity rather than inherent health risk — more pets of a breed means more veterinary encounters and more opportunity for adverse event reporting.

The 370.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 2,175 reports. This may indicate widespread use of the medication rather than a specific safety concern for Terrier - Jack Russell.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Terrier - Jack Russell?
There are 10,210 adverse event reports involving Terrier - Jack Russell in the FDA database, with 375 reports involving death (370.0% death rate). Terrier - Jack Russell ranks #18 by report volume.
What are the most common adverse reactions reported for Terrier - Jack Russell?
The most commonly reported adverse reactions for Terrier - Jack Russell are Vomiting (2,152 reports), Lethargy (see also Central nervous system depression in 'Neurological') (1,033 reports), Emesis (1,013 reports), Lack of efficacy (ectoparasite) - flea (957 reports), Diarrhoea (676 reports).
What drugs are most frequently associated with Terrier - Jack Russell adverse events?
The drugs most frequently referenced in Terrier - Jack Russell adverse event reports are Milbemycin Oxime + Spinosad (2,175 reports), Spinosad (1,043 reports), Ivermectin + Pyrantel As Pamoate Salt (872 reports), Afoxolaner (641 reports), Moxidectin (488 reports).
What is the average age of Terrier - Jack Russell in adverse event reports?
The average age of Terrier - Jack Russell at the time of adverse event reports is 6.8 years, with an average weight of 8.6 kg (19.0 lbs).
Does a high number of adverse event reports mean Terrier - Jack Russell is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Jack Russell safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Terrier - Jack Russell ranks #18 by total report volume. Death rate (370.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial