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Breed profile · FDA CVM July 2026 extract

Retriever (unspecified) adverse-event record

Adverse-event filings for Retriever (unspecified) (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#56 of 510
by report volume (all breeds)
3,492
FDA CVM reports on file
1.9%
death-coded share of reports
#261 of 275
by death-coded share (≥50 reports)

How the 3,492 reports break down

By recorded gender -- every report on file for Retriever (unspecified), no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 180 135 90 45 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Retriever (unspecified) drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Retriever (unspecified) ranks #56 of 510 by total reports (3,492) and #261 of 275 by death-coded share (1.9%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#56
This breed, reports of 510
#261
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Retriever (unspecified) has 3,492 reports now versus 3,466 in that prior snapshot: 26 more (0.8%).

Report change
+26
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Retriever (unspecified) changes

Total Reports

3,492

High report volume

Deaths Reported

67

of 3,492 reports

Death-coded share of reports

1.9%

Lowest death-coded share

Avg Age at Report

4.5 yr

29.0 kg avg weight

Breed Safety Scorecard

A+ (94/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate A+
1.9%

Share of reports coded as a fatality

Euthanasia rate A+
0.9%

Share of reports resulting in euthanasia

Full recovery rate A+
55.5%

Share of reports coded "Recovered/Normal"

5-year trend A
-43%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Retriever (unspecified) death-coded reports 1.9%
Cross-breed median

1.9% of 3,492 retriever (unspecified) reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Retriever (unspecified)'s death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

2% 5th percentile Higher share than 5% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Retriever (unspecified) 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Retriever (unspecified) among report-volume vs. death-rate peers

Every breed shown has at least 50 filed reports. Volume reflects how often a breed is reported, not how common it is; death rate is the share of a breed's own reports coded as a death outcome.

Source: FDA openFDA Animal & Veterinary Adverse Events database 2×2 strategic matrix plotting 30 entities by Total Reports (X) and Death Rate (%) (Y), with a crosshair dividing the plot into four quadrants. High volume, high death rateLow volume, high death rateHigh volume, low death rateLow volume, low death rate 020,00040,00060,00080,000100,000 0%5%10%15% Total Reports Death Rate (%) Retriever (unspecified) vs. all breeds, report volume and death-coded share Retriever - Labrador-93675, 3.7%Crossbred Canine/dog-70591, 3.2%Domestic Shorthair-65226, 7.2%Dog (unknown)-48820, 8.8%Retriever - Golden-35980, 3.7%Shepherd Dog - German-32220, 4.4%Chihuahua-31521, 4.2%Terrier - Yorkshire-24924, 3.7%Shih Tzu-24405, 3.6%Boxer (German Boxer)-19405, 4.4%Beagle-17970, 3.6%Pit Bull-17865, 3.1%Shepherd Dog - Australian-16274, 3.7%Terrier (unspecified)-14058, 3.1%Maltese-13940, 3.2%Dachshund (unspecified)-13512, 4.6%Cat (unknown)-13248, 9.3%Terrier - Jack Russell-10423, 3.7%Collie - Border-10130, 4.3%Siberian Husky-9811, 4.5%Domestic Longhair-9615, 7%Pug-9224, 5.2%Spitz - German Pomeranian-9086, 4.9%Terrier - Bull - American Pit-8769, 4.7%Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)-7871, 3.6%Terrier - Boston-7737, 4.5%Spaniel - Cocker American-7640, 4%Domestic (unspecified)-7576, 13.4%Poodle (unspecified)-7534, 3.4%Schnauzer - Miniature-7513, 4.4%
Source: FDA openFDA Animal & Veterinary Adverse Events database
Average weight at time of report: 29.0 kg (63.9 lbs)

Top Reported Reactions

Emesis 1,233
Vomiting 570
Lethargy (see also Central nervous system depression in 'Neurological') 325
Lack of efficacy (endoparasite) - heartworm 223
Diarrhoea 176
Lack of efficacy - NOS 157
Lack of efficacy (ectoparasite) - flea 140
Seizure NOS 106
Lack of efficacy (endoparasite) - hookworm 85
INEFFECTIVE, HEARTWORM LARVAE 67
Anorexia 63
Ataxia 57
Panting 56
Weight loss 55
Other abnormal test result NOS 55

Most Referenced Drugs

Milbemycin Oxime + Spinosad 1,359
Spinosad 836
Pyrantel Pamoate;Sarolaner 270
Moxidectin 251
Milbemycin Oxime + Praziquantel 172
Ivermectin 124
Fluralaner Chew Tablets 105
Sarolaner 97
Oclacitinib Maleate 94
Carprofen 87
Bedinvetmab 81
Milbemycin Oxime 64
Selamectin 49
Ivermectin + Pyrantel As Pamoate Salt 49
Melarsomine Dihydrochloride 38

Outcome Breakdown

Recovered/Normal
1,937 (55.4%)
Ongoing
756 (21.6%)
Outcome Unknown
547 (15.7%)
Recovered with Sequela
187 (5.4%)
Died
36 (1.0%)
Euthanized
31 (0.9%)

Gender Distribution

Female 1,790 (51.3%)
Male 1,665 (47.7%)
Unknown 32 (0.9%)
Mixed 5 (0.1%)

Reports by Year

Year Reports Trend
2010 26
2011 625
2012 1,165
2013 101
2014 100
2015 103
2016 95
2017 142
2018 139
2019 178
2020 171
2021 180
2022 98
2023 112
2024 132
2025 103
2026 22

Retriever (unspecified): low death-coded share in the FDA CVM extract

Signature read: Retriever (unspecified)'s 1.9% death-coded share is in the lower third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Retriever (unspecified) sits at #56 of 510 by report volume among all breeds and #50 of 298 among dog breeds, with 3,492 reports and 67 (1.9%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #261 of 275. Mean age at report: 4.5 years, average weight 29.0 kg (63.9 lbs).

Top reported signs: Emesis (1,233), Vomiting (570), Lethargy (see also Central nervous system depression in 'Neurological') (325). Most-referenced drug: Milbemycin Oxime + Spinosad (1,359 reports), followed by Spinosad (836) and Pyrantel Pamoate;Sarolaner (270).

Outcome coding on 3,494 status-recorded reports is dominated by Recovered/Normal (55.4%). Annual submissions ranged 22-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Greyhound
3,717 reports · 3.8% death-coded
Spaniel (unspecified)
3,209 reports · 4.8% death-coded
Pinscher - Miniature
3,776 reports · 5.2% death-coded
Lhasa Apso
3,196 reports · 3.7% death-coded
Collie (unspecified)
3,131 reports · 4.8% death-coded
Terrier - Rat
3,078 reports · 4.3% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Retriever (unspecified) drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (1.9% death-coded here).

Hanovarian 2.2% · Horse Turkish Angora 1.3% · Cat Warmblood - Dutch 2.7% · Horse Oldenburg 2.8% · Horse

Similar average weight

Nearest other-species breeds by reported average weight (29.0 kg here).

Fish (other) 32.4 kg · Fish Katahdin 32.4 kg · Sheep Nubian 32.8 kg · Goat Mixed (Sheep) 24.9 kg · Sheep

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Retriever (unspecified)? ▼
There are 3,492 adverse event reports involving Retriever (unspecified) in the FDA database, of which 67 were death-coded (1.9% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Retriever (unspecified) ranks #56 of 510 by report volume among all breeds PlainBreed indexes (#50 of 298 among dog breeds).
Where does Retriever (unspecified) sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Retriever (unspecified) is #56 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #50 of 298. Among breeds with at least 50 reports, its death-coded share ranks #261 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Retriever (unspecified)? ▼
The most commonly reported adverse reactions for Retriever (unspecified) are Emesis (1,233 reports), Vomiting (570 reports), Lethargy (see also Central nervous system depression in 'Neurological') (325 reports), Lack of efficacy (endoparasite) - heartworm (223 reports), Diarrhoea (176 reports).
What drugs are most frequently associated with Retriever (unspecified) adverse events? ▼
The drugs most frequently referenced in Retriever (unspecified) adverse event reports are Milbemycin Oxime + Spinosad (1,359 reports), Spinosad (836 reports), Pyrantel Pamoate;Sarolaner (270 reports), Moxidectin (251 reports), Milbemycin Oxime + Praziquantel (172 reports).
What is the average age of Retriever (unspecified) in adverse event reports? ▼
The average age of Retriever (unspecified) at the time of adverse event reports is 4.5 years, with an average weight of 29.0 kg (63.9 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Retriever (unspecified) (Dog), extract as of July 2026 extract. 3,492 reports · 67 death-coded (1.9% of reports, not a mortality rate) · #56 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →