Total Reports
3,439
FDA CVM filings
Dog /
FDA CVM · 2025 release 3,439 reports on file
Retriever (unspecified) - FDA Adverse Event Profile
Adverse-event records for Retriever (unspecified) (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Retriever (unspecified) is #56 by FDA report volume; 1.9% of its 3,439 reports (65) were death-coded.
- #56
- most-reported dog breed
- 1.9%
- death-coded report share
- 1,233
- Emesis - top reaction
- 4.4 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
65
of 3,439 reports
Death Rate
1.9%
death-coded share
Avg Age at Report
4.4 yr
29.0 kg avg weight
Death-Coded Outcome Share
Retriever (unspecified) death-coded reports 1.9%
Cross-breed median
1.9% of 3,439 retriever (unspecified) reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 29.0 kg (63.9 lbs)
Top Reported Reactions
Emesis 1,233
Vomiting 562
Lethargy (see also Central nervous system depression in 'Neurological') 325
Lack of efficacy (endoparasite) - heartworm 216
Diarrhoea 172
Lack of efficacy - NOS 156
Lack of efficacy (ectoparasite) - flea 138
Seizure NOS 103
Lack of efficacy (endoparasite) - hookworm 83
INEFFECTIVE, HEARTWORM LARVAE 67
Anorexia 62
Panting 56
Ataxia 56
Weight loss 55
Other abnormal test result NOS 54
Most Referenced Drugs
Milbemycin Oxime + Spinosad 1,357
Spinosad 836
Pyrantel Pamoate;Sarolaner 251
Moxidectin 246
Milbemycin Oxime + Praziquantel 169
Ivermectin 123
Fluralaner Chew Tablets 105
Sarolaner 93
Oclacitinib Maleate 89
Carprofen 86
Bedinvetmab 67
Milbemycin Oxime 64
Ivermectin + Pyrantel As Pamoate Salt 50
Selamectin 49
Melarsomine Dihydrochloride 38
Outcome Breakdown
Recovered/Normal
1,928 (56.0%)
Ongoing
726 (21.1%)
Outcome Unknown
535 (15.5%)
Recovered with Sequela
187 (5.4%)
Died
36 (1.0%)
Euthanized
29 (0.8%)
Gender Distribution
Female 1,764 (51.3%)
Male 1,639 (47.7%)
Unknown 31 (0.9%)
Mixed 5 (0.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 26 | |
| 2011 | 625 | |
| 2012 | 1,165 | |
| 2013 | 101 | |
| 2014 | 100 | |
| 2015 | 103 | |
| 2016 | 95 | |
| 2017 | 142 | |
| 2018 | 139 | |
| 2019 | 178 | |
| 2020 | 171 | |
| 2021 | 180 | |
| 2022 | 98 | |
| 2023 | 112 | |
| 2024 | 130 | |
| 2025 | 74 | |
Retriever (unspecified) Pet Health Insights
Retriever (unspecified) accounts for 3,439 FDA adverse event reports, ranking #56 by volume among dog breeds, with 65 reports (1.9%) coded as a death outcome. Mean age at report: 4.4 years, average weight 29.0 kg (63.9 lbs).
Top reported signs: Emesis (1,233), Vomiting (562), Lethargy (see also Central nervous system depression in 'Neurological') (325). Most-referenced drug: Milbemycin Oxime + Spinosad (1,357 reports), followed by Spinosad (836) and Pyrantel Pamoate;Sarolaner (251).
Outcome coding on 3,441 status-recorded reports is dominated by Recovered/Normal (56.0%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Greyhound
3,648 reports · 3.7% death rate
Pinscher - Miniature
3,700 reports · 5.1% death rate
Lhasa Apso
3,154 reports · 3.6% death rate
Pointing Dog - German Short-haired
3,752 reports · 3.3% death rate
Collie (unspecified)
3,080 reports · 4.8% death rate
Spaniel (unspecified)
3,074 reports · 4.9% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Retriever (unspecified)? ▼
There are 3,439 adverse event reports involving Retriever (unspecified) in the FDA database, with 65 reports involving death (1.9% death rate). Retriever (unspecified) ranks #56 by report volume.
What are the most common adverse reactions reported for Retriever (unspecified)? ▼
The most commonly reported adverse reactions for Retriever (unspecified) are Emesis (1,233 reports), Vomiting (562 reports), Lethargy (see also Central nervous system depression in 'Neurological') (325 reports), Lack of efficacy (endoparasite) - heartworm (216 reports), Diarrhoea (172 reports).
What drugs are most frequently associated with Retriever (unspecified) adverse events? ▼
The drugs most frequently referenced in Retriever (unspecified) adverse event reports are Milbemycin Oxime + Spinosad (1,357 reports), Spinosad (836 reports), Pyrantel Pamoate;Sarolaner (251 reports), Moxidectin (246 reports), Milbemycin Oxime + Praziquantel (169 reports).
What is the average age of Retriever (unspecified) in adverse event reports? ▼
The average age of Retriever (unspecified) at the time of adverse event reports is 4.4 years, with an average weight of 29.0 kg (63.9 lbs).
Does a high number of adverse event reports mean Retriever (unspecified) is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Retriever (unspecified) safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.