Total Reports
2,187
FDA CVM filings
Dog /
FDA CVM · 2025 release 2,187 reports on file
Spaniel - Springer English - FDA Adverse Event Profile
Adverse-event records for Spaniel - Springer English (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Spaniel - Springer English is #78 by FDA report volume; 3.9% of its 2,187 reports (85) were death-coded.
- #78
- most-reported dog breed
- 3.9%
- death-coded report share
- 317
- Vomiting - top reaction
- 6.0 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
85
of 2,187 reports
Death Rate
3.9%
death-coded share
Avg Age at Report
6.0 yr
21.6 kg avg weight
Death-Coded Outcome Share
Spaniel - Springer English death-coded reports 3.9%
Cross-breed median
3.9% of 2,187 spaniel - springer english reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 21.6 kg (47.6 lbs)
Top Reported Reactions
Vomiting 317
Lethargy (see also Central nervous system depression in 'Neurological') 193
Lack of efficacy (endoparasite) - hookworm 173
Diarrhoea 157
Lack of efficacy - NOS 143
Emesis 132
Digestive tract disorder NOS 131
Seizure NOS 96
Lack of efficacy (ectoparasite) - tick NOS 93
INEFFECTIVE, HEARTWORM LARVAE 92
Lack of efficacy (ectoparasite) - flea 85
Lack of efficacy (bacteria) - NOS 84
Other abnormal test result NOS 75
Lack of efficacy (bacteria) - Borrelia 75
Lack of efficacy (endoparasite) - heartworm 73
Most Referenced Drugs
Ivermectin + Pyrantel As Pamoate Salt 347
Afoxolaner 246
Milbemycin Oxime + Spinosad 234
Pyrantel Pamoate;Sarolaner 140
Fluralaner Chew Tablets 123
Oclacitinib Maleate 93
Trilostane 92
Fluralaner 13.64% 12-Week Chew 84
Moxidectin 72
Milbemycin Oxime + Praziquantel 72
Spinosad 63
Sarolaner 57
Carprofen 48
Bedinvetmab 39
Lufenuron + Milbemycin Oxime 38
Outcome Breakdown
Outcome Unknown
828 (37.8%)
Recovered/Normal
616 (28.1%)
Ongoing
574 (26.2%)
Recovered with Sequela
87 (4.0%)
Euthanized
56 (2.6%)
Died
29 (1.3%)
Gender Distribution
Female 1,103 (50.4%)
Male 1,050 (48.0%)
Unknown 30 (1.4%)
Mixed 4 (0.2%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 3 | |
| 2011 | 56 | |
| 2012 | 169 | |
| 2013 | 142 | |
| 2014 | 164 | |
| 2015 | 182 | |
| 2016 | 171 | |
| 2017 | 186 | |
| 2018 | 163 | |
| 2019 | 177 | |
| 2020 | 127 | |
| 2021 | 139 | |
| 2022 | 135 | |
| 2023 | 126 | |
| 2024 | 159 | |
| 2025 | 88 | |
Spaniel - Springer English Pet Health Insights
Spaniel - Springer English accounts for 2,187 FDA adverse event reports, ranking #78 by volume among dog breeds, with 85 reports (3.9%) coded as a death outcome. Mean age at report: 6.0 years, average weight 21.6 kg (47.6 lbs).
Top reported signs: Vomiting (317), Lethargy (see also Central nervous system depression in 'Neurological') (193), Lack of efficacy (endoparasite) - hookworm (173). Most-referenced drug: Ivermectin + Pyrantel As Pamoate Salt (347 reports), followed by Afoxolaner (246) and Milbemycin Oxime + Spinosad (234).
Outcome coding on 2,190 status-recorded reports is dominated by Outcome Unknown (37.8%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne))
2,087 reports · 4.4% death rate
Catahoula Leopard Dog
2,316 reports · 2.3% death rate
Chow Chow
2,029 reports · 6.4% death rate
Bulldog - American
2,409 reports · 4.9% death rate
Terrier - Cairn
1,928 reports · 4.7% death rate
Weimaraner
2,480 reports · 4.6% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Spaniel - Springer English? ▼
There are 2,187 adverse event reports involving Spaniel - Springer English in the FDA database, with 85 reports involving death (3.9% death rate). Spaniel - Springer English ranks #78 by report volume.
What are the most common adverse reactions reported for Spaniel - Springer English? ▼
The most commonly reported adverse reactions for Spaniel - Springer English are Vomiting (317 reports), Lethargy (see also Central nervous system depression in 'Neurological') (193 reports), Lack of efficacy (endoparasite) - hookworm (173 reports), Diarrhoea (157 reports), Lack of efficacy - NOS (143 reports).
What drugs are most frequently associated with Spaniel - Springer English adverse events? ▼
The drugs most frequently referenced in Spaniel - Springer English adverse event reports are Ivermectin + Pyrantel As Pamoate Salt (347 reports), Afoxolaner (246 reports), Milbemycin Oxime + Spinosad (234 reports), Pyrantel Pamoate;Sarolaner (140 reports), Fluralaner Chew Tablets (123 reports).
What is the average age of Spaniel - Springer English in adverse event reports? ▼
The average age of Spaniel - Springer English at the time of adverse event reports is 6.0 years, with an average weight of 21.6 kg (47.6 lbs).
Does a high number of adverse event reports mean Spaniel - Springer English is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Spaniel - Springer English safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.