Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
2,283
Total Reports
170
Deaths Reported
740.0%
Death Rate
7.1 yr
Avg Age at Report
Average weight at time of report: 6.1 kg (13.5 lbs)
Top Reported Reactions
Vomiting 299
Lack of efficacy (ectoparasite) - flea 220
Lethargy (see also Central nervous system depression in 'Neurological') 213
Anorexia 143
Emesis 141
Panting 138
Behavioural disorder NOS 136
Application site hair loss 135
Diarrhoea 134
Application site alopecia 118
Lack of efficacy - NOS 112
Weight loss 111
Hyperactivity 100
Vocalisation 95
Not eating 89
Most Referenced Drugs
Spinosad 297
Selamectin 294
Nitenpyram 267
Fluralaner Spot-On Solution 195
Imidacloprid + Moxidectin 139
Selamectin;Sarolaner 138
Frunevetmab 118
Cefovecin 94
Buprenorphine 89
Robenacoxib 66
Maropitant Citrate 64
Bexagliflozin 50
Fluralaner/Moxidectin Spot-On 48
Emodepside + Praziquantel 46
Velagliflozin Proline Monohydrate 44
Outcome Breakdown
Ongoing
667 (30.9%)
Outcome Unknown
659 (30.6%)
Recovered/Normal
641 (29.7%)
Died
99 (4.6%)
Euthanized
71 (3.3%)
Recovered with Sequela
19 (0.9%)
Gender Distribution
Male 1,490 (65.3%)
Female 744 (32.6%)
Unknown 41 (1.8%)
Mixed 8 (0.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 83 | |
| 2011 | 65 | |
| 2012 | 111 | |
| 2013 | 144 | |
| 2014 | 161 | |
| 2015 | 138 | |
| 2016 | 124 | |
| 2017 | 164 | |
| 2018 | 153 | |
| 2019 | 150 | |
| 2020 | 128 | |
| 2021 | 110 | |
| 2022 | 118 | |
| 2023 | 221 | |
| 2024 | 245 | |
| 2025 | 168 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #77 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.