Total Reports
2,283
FDA CVM filings
Cat /
FDA CVM · 2025 release 2,283 reports on file
Maine Coon - FDA Adverse Event Profile
Adverse-event records for Maine Coon (Cat) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 2,283 reports on file, Maine Coon sits at #77 among cat breeds by volume; death-coded share is 7.4% (170 reports).
- #77
- most-reported cat breed
- 7.4%
- death-coded report share
- 299
- Vomiting - top reaction
- 7.1 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
170
of 2,283 reports
Death Rate
7.4%
death-coded share
Avg Age at Report
7.1 yr
6.1 kg avg weight
Death-Coded Outcome Share
Maine Coon death-coded reports 7.4%
Cross-breed median
7.4% of 2,283 maine coon reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 6.1 kg (13.5 lbs)
Top Reported Reactions
Vomiting 299
Lack of efficacy (ectoparasite) - flea 220
Lethargy (see also Central nervous system depression in 'Neurological') 213
Anorexia 143
Emesis 141
Panting 138
Behavioural disorder NOS 136
Application site hair loss 135
Diarrhoea 134
Application site alopecia 118
Lack of efficacy - NOS 112
Weight loss 111
Hyperactivity 100
Vocalisation 95
Not eating 89
Most Referenced Drugs
Spinosad 297
Selamectin 294
Nitenpyram 267
Fluralaner Spot-On Solution 195
Imidacloprid + Moxidectin 139
Selamectin;Sarolaner 138
Frunevetmab 118
Cefovecin 94
Buprenorphine 89
Robenacoxib 66
Maropitant Citrate 64
Bexagliflozin 50
Fluralaner/Moxidectin Spot-On 48
Emodepside + Praziquantel 46
Velagliflozin Proline Monohydrate 44
Outcome Breakdown
Ongoing
667 (30.9%)
Outcome Unknown
659 (30.6%)
Recovered/Normal
641 (29.7%)
Died
99 (4.6%)
Euthanized
71 (3.3%)
Recovered with Sequela
19 (0.9%)
Gender Distribution
Male 1,490 (65.3%)
Female 744 (32.6%)
Unknown 41 (1.8%)
Mixed 8 (0.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 83 | |
| 2011 | 65 | |
| 2012 | 111 | |
| 2013 | 144 | |
| 2014 | 161 | |
| 2015 | 138 | |
| 2016 | 124 | |
| 2017 | 164 | |
| 2018 | 153 | |
| 2019 | 150 | |
| 2020 | 128 | |
| 2021 | 110 | |
| 2022 | 118 | |
| 2023 | 221 | |
| 2024 | 245 | |
| 2025 | 168 | |
Maine Coon Pet Health Insights
Maine Coon accounts for 2,283 FDA adverse event reports, ranking #77 by volume among cat breeds, with 170 reports (7.4%) coded as a death outcome. Mean age at report: 7.1 years, average weight 6.1 kg (13.5 lbs).
Top reported signs: Vomiting (299), Lack of efficacy (ectoparasite) - flea (220), Lethargy (see also Central nervous system depression in 'Neurological') (213). Most-referenced drug: Spinosad (297 reports), followed by Selamectin (294) and Nitenpyram (267).
Outcome coding on 2,156 status-recorded reports is dominated by Ongoing (30.9%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Cat Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Maine Coon? ▼
There are 2,283 adverse event reports involving Maine Coon in the FDA database, with 170 reports involving death (7.4% death rate). Maine Coon ranks #77 by report volume.
What are the most common adverse reactions reported for Maine Coon? ▼
The most commonly reported adverse reactions for Maine Coon are Vomiting (299 reports), Lack of efficacy (ectoparasite) - flea (220 reports), Lethargy (see also Central nervous system depression in 'Neurological') (213 reports), Anorexia (143 reports), Emesis (141 reports).
What drugs are most frequently associated with Maine Coon adverse events? ▼
The drugs most frequently referenced in Maine Coon adverse event reports are Spinosad (297 reports), Selamectin (294 reports), Nitenpyram (267 reports), Fluralaner Spot-On Solution (195 reports), Imidacloprid + Moxidectin (139 reports).
What is the average age of Maine Coon in adverse event reports? ▼
The average age of Maine Coon at the time of adverse event reports is 7.1 years, with an average weight of 6.1 kg (13.5 lbs).
Does a high number of adverse event reports mean Maine Coon is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Maine Coon safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.