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Breed profile · FDA CVM July 2026 extract

Boxer (German Boxer) adverse-event record

Adverse-event filings for Boxer (German Boxer) (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#10 of 510
by report volume (all breeds)
19,405
FDA CVM reports on file
4.4%
death-coded share of reports
#157 of 275
by death-coded share (≥50 reports)

How the 19,405 reports break down

By recorded gender -- every report on file for Boxer (German Boxer), no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 1,221 915.75 610.5 305.25 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Boxer (German Boxer) drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Boxer (German Boxer) ranks #10 of 510 by total reports (19,405) and #157 of 275 by death-coded share (4.4%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#10
This breed, reports of 510
#157
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Boxer (German Boxer) has 19,405 reports now versus 19,246 in that prior snapshot: 159 more (0.8%).

Report change
+159
Death-coded reports
+6
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Boxer (German Boxer) changes

Total Reports

19,405

Highest-reported breed

Deaths Reported

862

of 19,405 reports

Death-coded share of reports

4.4%

Below-median death-coded share

Avg Age at Report

4.5 yr

28.0 kg avg weight

Breed Safety Scorecard

C+ (62/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate C-
4.4%

Share of reports coded as a fatality

Euthanasia rate C-
2.1%

Share of reports resulting in euthanasia

Full recovery rate B
33.9%

Share of reports coded "Recovered/Normal"

5-year trend B+
-17%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Boxer (German Boxer) death-coded reports 4.4%
Cross-breed median

4.4% of 19,405 boxer (german boxer) reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Boxer (German Boxer)'s death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

4% 43rd percentile Higher share than 43% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Boxer (German Boxer) 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Boxer (German Boxer) among report-volume vs. death-rate peers

Every breed shown has at least 50 filed reports. Volume reflects how often a breed is reported, not how common it is; death rate is the share of a breed's own reports coded as a death outcome.

Source: FDA openFDA Animal & Veterinary Adverse Events database 2×2 strategic matrix plotting 30 entities by Total Reports (X) and Death Rate (%) (Y), with a crosshair dividing the plot into four quadrants. High volume, high death rateLow volume, high death rateHigh volume, low death rateLow volume, low death rate 020,00040,00060,00080,000100,000 0%5%10%15% Total Reports Death Rate (%) Boxer (German Boxer) vs. all breeds, report volume and death-coded share Retriever - Labrador-93675, 3.7%Crossbred Canine/dog-70591, 3.2%Domestic Shorthair-65226, 7.2%Dog (unknown)-48820, 8.8%Retriever - Golden-35980, 3.7%Shepherd Dog - German-32220, 4.4%Chihuahua-31521, 4.2%Terrier - Yorkshire-24924, 3.7%Shih Tzu-24405, 3.6%Boxer (German Boxer)-19405, 4.4%Beagle-17970, 3.6%Pit Bull-17865, 3.1%Shepherd Dog - Australian-16274, 3.7%Terrier (unspecified)-14058, 3.1%Maltese-13940, 3.2%Dachshund (unspecified)-13512, 4.6%Cat (unknown)-13248, 9.3%Terrier - Jack Russell-10423, 3.7%Collie - Border-10130, 4.3%Siberian Husky-9811, 4.5%Domestic Longhair-9615, 7%Pug-9224, 5.2%Spitz - German Pomeranian-9086, 4.9%Terrier - Bull - American Pit-8769, 4.7%Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)-7871, 3.6%Terrier - Boston-7737, 4.5%Spaniel - Cocker American-7640, 4%Domestic (unspecified)-7576, 13.4%Poodle (unspecified)-7534, 3.4%Schnauzer - Miniature-7513, 4.4%
Source: FDA openFDA Animal & Veterinary Adverse Events database
Average weight at time of report: 28.0 kg (61.7 lbs)

Top Reported Reactions

Vomiting 4,057
Lethargy (see also Central nervous system depression in 'Neurological') 2,285
Emesis 2,239
INEFFECTIVE, HEARTWORM LARVAE 1,208
Lack of efficacy (endoparasite) - heartworm 1,205
Diarrhoea 1,181
Lack of efficacy - NOS 1,018
Lack of efficacy (endoparasite) - hookworm 922
Seizure NOS 803
Anorexia 713
Lack of efficacy (ectoparasite) - flea 617
Hives (see also 'Skin') 559
Digestive tract disorder NOS 508
Not eating 481
Other abnormal test result NOS 478

Most Referenced Drugs

Milbemycin Oxime + Spinosad 4,959
Ivermectin + Pyrantel As Pamoate Salt 1,879
Moxidectin 1,467
Spinosad 1,380
Afoxolaner 916
Pyrantel Pamoate;Sarolaner 788
Oclacitinib Maleate 764
Milbemycin Oxime + Praziquantel 714
Fluralaner Chew Tablets 620
Carprofen 537
Bedinvetmab 468
Trilostane 453
Fluralaner 13.64% 12-Week Chew 363
Sarolaner 333
Melarsomine Dihydrochloride 306

Outcome Breakdown

Recovered/Normal
6,586 (36.9%)
Outcome Unknown
5,189 (29.1%)
Ongoing
4,275 (23.9%)
Recovered with Sequela
941 (5.3%)
Died
457 (2.6%)
Euthanized
405 (2.3%)

Gender Distribution

Male 9,529 (49.1%)
Female 9,527 (49.1%)
Unknown 301 (1.6%)
Mixed 48 (0.2%)

Reports by Year

Year Reports Trend
2010 826
2011 1,138
2012 1,645
2013 1,622
2014 1,527
2015 1,479
2016 1,466
2017 1,358
2018 1,260
2019 1,221
2020 1,143
2021 967
2022 916
2023 872
2024 1,044
2025 800
2026 121

Boxer (German Boxer): high-volume FDA adverse-event cohort

Signature read: 19,405 reports place Boxer (German Boxer) in the upper third of breed filing volume (#10 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Boxer (German Boxer) sits at #10 of 510 by report volume among all breeds and #9 of 298 among dog breeds, with 19,405 reports and 862 (4.4%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #157 of 275. Mean age at report: 4.5 years, average weight 28.0 kg (61.7 lbs).

Top reported signs: Vomiting (4,057), Lethargy (see also Central nervous system depression in 'Neurological') (2,285), Emesis (2,239). Most-referenced drug: Milbemycin Oxime + Spinosad (4,959 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (1,879) and Moxidectin (1,467).

Outcome coding on 17,853 status-recorded reports is dominated by Recovered/Normal (36.9%). Annual submissions ranged 121-2,026 across 17 years on file.

Boxer (German Boxer) Reporting Concentration Profile

Boxer (German Boxer) is a high-volume FDA CVM cohort (19,405 reports) - enough filings to measure how concentrated the reaction and drug mix is, not just the headline totals. Across 20 named reaction terms in the stored top list, the leading three (Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Emesis) account for 42.0% of listed reaction mentions. The Herfindahl index on that list is 0.087 (1.0 = a single reaction owns every mention; lower = a broader clinical mix).

On the drug side, 20 referenced products appear in the top list; the leading three (Milbemycin Oxime + Spinosad, Ivermectin + Pyrantel As Pamoate Salt, Moxidectin) cover 48.2% of those mentions. That multi-product footprint is the profile thin-report breeds cannot show - their pages stop at a short bar list because the sample cannot support a concentration read.

Outcome coding on 17,853 status-recorded filings splits roughly 4.8% severe (died or euthanized - 862 reports) versus 42.2% recovered or recovered-with-sequela (7,527). Read that split next to the 4.4% death-coded share above - both track reporting severity bias in a popular breed, not a proven mortality rate.

Peak filing year was 2012 (1,645 reports); the lightest year on file was 2026 (121). From 2024 to 2025, annual volume fell 23.4% (1,044 → 800). Year-to-year swings at this volume usually track product launches, owner awareness, and reporting campaigns more than sudden breed-health shocks.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Beagle
17,970 reports · 3.6% death-coded
Pit Bull
17,865 reports · 3.1% death-coded
Shepherd Dog - Australian
16,274 reports · 3.7% death-coded
Shih Tzu
24,405 reports · 3.6% death-coded
Terrier (unspecified)
14,058 reports · 3.1% death-coded
Maltese
13,940 reports · 3.2% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Boxer (German Boxer) drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (4.4% death-coded here).

Bengal 4.6% · Cat Siberian 4.2% · Cat Scottish Fold Longhair 4.8% · Cat British cat 3.8% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (28.0 kg here).

Mixed (Sheep) 24.9 kg · Sheep Fish (other) 32.4 kg · Fish Katahdin 32.4 kg · Sheep Nubian 32.8 kg · Goat

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Boxer (German Boxer)? ▼
There are 19,405 adverse event reports involving Boxer (German Boxer) in the FDA database, of which 862 were death-coded (4.4% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Boxer (German Boxer) ranks #10 of 510 by report volume among all breeds PlainBreed indexes (#9 of 298 among dog breeds).
Where does Boxer (German Boxer) sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Boxer (German Boxer) is #10 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #9 of 298. Among breeds with at least 50 reports, its death-coded share ranks #157 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Boxer (German Boxer)? ▼
The most commonly reported adverse reactions for Boxer (German Boxer) are Vomiting (4,057 reports), Lethargy (see also Central nervous system depression in 'Neurological') (2,285 reports), Emesis (2,239 reports), INEFFECTIVE, HEARTWORM LARVAE (1,208 reports), Lack of efficacy (endoparasite) - heartworm (1,205 reports).
What drugs are most frequently associated with Boxer (German Boxer) adverse events? ▼
The drugs most frequently referenced in Boxer (German Boxer) adverse event reports are Milbemycin Oxime + Spinosad (4,959 reports), Ivermectin + Pyrantel As Pamoate Salt (1,879 reports), Moxidectin (1,467 reports), Spinosad (1,380 reports), Afoxolaner (916 reports).
What is the average age of Boxer (German Boxer) in adverse event reports? ▼
The average age of Boxer (German Boxer) at the time of adverse event reports is 4.5 years, with an average weight of 28.0 kg (61.7 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Boxer (German Boxer) (Dog), extract as of July 2026 extract. 19,405 reports · 862 death-coded (4.4% of reports, not a mortality rate) · #10 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →