Total Reports
1,253
FDA CVM filings
Dog /
FDA CVM · 2025 release 1,253 reports on file
Saint Bernard Dog - FDA Adverse Event Profile
Adverse-event records for Saint Bernard Dog (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Saint Bernard Dog ranks #98 by report volume among dog breeds - 98 of 1,253 reports (7.8%) recorded a death outcome.
- #98
- most-reported dog breed
- 7.8%
- death-coded report share
- 218
- Vomiting - top reaction
- 4.4 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
98
of 1,253 reports
Death Rate
7.8%
death-coded share
Avg Age at Report
4.4 yr
50.6 kg avg weight
Death-Coded Outcome Share
Saint Bernard Dog death-coded reports 7.8%
Cross-breed median
7.8% of 1,253 saint bernard dog reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 50.6 kg (111.6 lbs)
Top Reported Reactions
Vomiting 218
INEFFECTIVE, HEARTWORM LARVAE 94
Diarrhoea 89
Emesis 85
Lethargy (see also Central nervous system depression in 'Neurological') 84
Seizure NOS 84
Lack of efficacy - NOS 74
Lack of efficacy (endoparasite) - heartworm 67
Anorexia 58
Lack of efficacy (ectoparasite) - flea 53
Underdose 47
Death by euthanasia 46
Death 43
Weight loss 41
Lack of efficacy (endoparasite) - hookworm 40
Most Referenced Drugs
Milbemycin Oxime + Spinosad 211
Ivermectin + Pyrantel As Pamoate Salt 157
Carprofen 91
Pyrantel Pamoate;Sarolaner 88
Afoxolaner 79
Milbemycin Oxime + Praziquantel 78
Spinosad 69
Fluralaner Chew Tablets 63
Bedinvetmab 62
Moxidectin 58
Fluralaner 13.64% 12-Week Chew 52
Oclacitinib Maleate 35
Sarolaner 33
Gabapentin 29
Prednisone 28
Outcome Breakdown
Outcome Unknown
394 (34.0%)
Ongoing
314 (27.1%)
Recovered/Normal
313 (27.0%)
Died
52 (4.5%)
Euthanized
46 (4.0%)
Recovered with Sequela
39 (3.4%)
Gender Distribution
Male 692 (55.2%)
Female 523 (41.7%)
Unknown 33 (2.6%)
Mixed 5 (0.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 52 | |
| 2011 | 75 | |
| 2012 | 81 | |
| 2013 | 88 | |
| 2014 | 60 | |
| 2015 | 77 | |
| 2016 | 82 | |
| 2017 | 96 | |
| 2018 | 100 | |
| 2019 | 81 | |
| 2020 | 76 | |
| 2021 | 59 | |
| 2022 | 63 | |
| 2023 | 84 | |
| 2024 | 105 | |
| 2025 | 74 | |
Saint Bernard Dog Pet Health Insights
Saint Bernard Dog accounts for 1,253 FDA adverse event reports, ranking #98 by volume among dog breeds, with 98 reports (7.8%) coded as a death outcome. Mean age at report: 4.4 years, average weight 50.6 kg (111.6 lbs).
Top reported signs: Vomiting (218), INEFFECTIVE, HEARTWORM LARVAE (94), Diarrhoea (89). Most-referenced drug: Milbemycin Oxime + Spinosad (211 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (157) and Carprofen (91).
Outcome coding on 1,158 status-recorded reports is dominated by Outcome Unknown (34.0%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Shar Pei
1,258 reports · 7.6% death rate
Newfoundland
1,261 reports · 7.2% death rate
Spaniel - Cocker English
1,243 reports · 2.5% death rate
Shepherd Dog (unspecified)
1,271 reports · 3.2% death rate
Ridgeback - Rhodesian
1,291 reports · 5.2% death rate
Coonhound (unspecified)
1,210 reports · 3.0% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Saint Bernard Dog? ▼
There are 1,253 adverse event reports involving Saint Bernard Dog in the FDA database, with 98 reports involving death (7.8% death rate). Saint Bernard Dog ranks #98 by report volume.
What are the most common adverse reactions reported for Saint Bernard Dog? ▼
The most commonly reported adverse reactions for Saint Bernard Dog are Vomiting (218 reports), INEFFECTIVE, HEARTWORM LARVAE (94 reports), Diarrhoea (89 reports), Emesis (85 reports), Lethargy (see also Central nervous system depression in 'Neurological') (84 reports).
What drugs are most frequently associated with Saint Bernard Dog adverse events? ▼
The drugs most frequently referenced in Saint Bernard Dog adverse event reports are Milbemycin Oxime + Spinosad (211 reports), Ivermectin + Pyrantel As Pamoate Salt (157 reports), Carprofen (91 reports), Pyrantel Pamoate;Sarolaner (88 reports), Afoxolaner (79 reports).
What is the average age of Saint Bernard Dog in adverse event reports? ▼
The average age of Saint Bernard Dog at the time of adverse event reports is 4.4 years, with an average weight of 50.6 kg (111.6 lbs).
Does a high number of adverse event reports mean Saint Bernard Dog is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Saint Bernard Dog safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.