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Breed profile · FDA CVM July 2026 extract

Collie (unspecified) adverse-event record

Adverse-event filings for Collie (unspecified) (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#60 of 510
by report volume (all breeds)
3,131
FDA CVM reports on file
4.8%
death-coded share of reports
#142 of 275
by death-coded share (≥50 reports)

How the 3,131 reports break down

By recorded gender -- every report on file for Collie (unspecified), no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 193 144.75 96.5 48.25 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Collie (unspecified) drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Collie (unspecified) ranks #60 of 510 by total reports (3,131) and #142 of 275 by death-coded share (4.8%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#60
This breed, reports of 510
#142
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Collie (unspecified) has 3,131 reports now versus 3,109 in that prior snapshot: 22 more (0.7%).

Report change
+22
Death-coded reports
+2
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Collie (unspecified) changes

Total Reports

3,131

High report volume

Deaths Reported

149

of 3,131 reports

Death-coded share of reports

4.8%

Below-median death-coded share

Avg Age at Report

5.8 yr

25.9 kg avg weight

Breed Safety Scorecard

C (57/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate D
4.8%

Share of reports coded as a fatality

Euthanasia rate C
2.0%

Share of reports resulting in euthanasia

Full recovery rate B-
33.0%

Share of reports coded "Recovered/Normal"

5-year trend C
+0%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Collie (unspecified) death-coded reports 4.8%
Cross-breed median

4.8% of 3,131 collie (unspecified) reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Collie (unspecified)'s death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

5% 48th percentile Higher share than 48% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Collie (unspecified) 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Collie (unspecified) among report-volume vs. death-rate peers

Every breed shown has at least 50 filed reports. Volume reflects how often a breed is reported, not how common it is; death rate is the share of a breed's own reports coded as a death outcome.

Source: FDA openFDA Animal & Veterinary Adverse Events database 2×2 strategic matrix plotting 30 entities by Total Reports (X) and Death Rate (%) (Y), with a crosshair dividing the plot into four quadrants. High volume, high death rateLow volume, high death rateHigh volume, low death rateLow volume, low death rate 020,00040,00060,00080,000100,000 0%5%10%15% Total Reports Death Rate (%) Collie (unspecified) vs. all breeds, report volume and death-coded share Retriever - Labrador-93675, 3.7%Crossbred Canine/dog-70591, 3.2%Domestic Shorthair-65226, 7.2%Dog (unknown)-48820, 8.8%Retriever - Golden-35980, 3.7%Shepherd Dog - German-32220, 4.4%Chihuahua-31521, 4.2%Terrier - Yorkshire-24924, 3.7%Shih Tzu-24405, 3.6%Boxer (German Boxer)-19405, 4.4%Beagle-17970, 3.6%Pit Bull-17865, 3.1%Shepherd Dog - Australian-16274, 3.7%Terrier (unspecified)-14058, 3.1%Maltese-13940, 3.2%Dachshund (unspecified)-13512, 4.6%Cat (unknown)-13248, 9.3%Terrier - Jack Russell-10423, 3.7%Collie - Border-10130, 4.3%Siberian Husky-9811, 4.5%Domestic Longhair-9615, 7%Pug-9224, 5.2%Spitz - German Pomeranian-9086, 4.9%Terrier - Bull - American Pit-8769, 4.7%Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)-7871, 3.6%Terrier - Boston-7737, 4.5%Spaniel - Cocker American-7640, 4%Domestic (unspecified)-7576, 13.4%Poodle (unspecified)-7534, 3.4%Schnauzer - Miniature-7513, 4.4%
Source: FDA openFDA Animal & Veterinary Adverse Events database
Average weight at time of report: 25.9 kg (57.1 lbs)

Top Reported Reactions

Vomiting 544
Emesis 342
Diarrhoea 294
Lethargy (see also Central nervous system depression in 'Neurological') 265
Lack of efficacy (endoparasite) - heartworm 185
INEFFECTIVE, HEARTWORM LARVAE 171
Lack of efficacy - NOS 165
Seizure NOS 155
Lack of efficacy (endoparasite) - hookworm 151
Lack of efficacy (ectoparasite) - flea 128
Anorexia 106
Ataxia 102
Other abnormal test result NOS 83
Digestive tract disorder NOS 82
Death by euthanasia 73

Most Referenced Drugs

Milbemycin Oxime + Spinosad 572
Ivermectin + Pyrantel As Pamoate Salt 298
Afoxolaner 230
Spinosad 209
Pyrantel Pamoate;Sarolaner 164
Milbemycin Oxime + Praziquantel 151
Fluralaner Chew Tablets 114
Moxidectin 108
Milbemycin Oxime 94
Carprofen 93
Bedinvetmab 92
Selamectin 73
Oclacitinib Maleate 69
Grapiprant 68
Sarolaner 65

Outcome Breakdown

Recovered/Normal
1,034 (35.9%)
Outcome Unknown
881 (30.6%)
Ongoing
691 (24.0%)
Recovered with Sequela
125 (4.3%)
Died
86 (3.0%)
Euthanized
63 (2.2%)

Gender Distribution

Female 1,568 (50.1%)
Male 1,462 (46.7%)
Unknown 91 (2.9%)
Mixed 10 (0.3%)

Reports by Year

Year Reports Trend
2010 127
2011 239
2012 343
2013 239
2014 219
2015 233
2016 207
2017 180
2018 184
2019 183
2020 180
2021 147
2022 135
2023 163
2024 193
2025 147
2026 12

Collie (unspecified): high-volume FDA adverse-event cohort

Signature read: 3,131 reports place Collie (unspecified) in the upper third of breed filing volume (#60 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Collie (unspecified) sits at #60 of 510 by report volume among all breeds and #53 of 298 among dog breeds, with 3,131 reports and 149 (4.8%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #142 of 275. Mean age at report: 5.8 years, average weight 25.9 kg (57.1 lbs).

Top reported signs: Vomiting (544), Emesis (342), Diarrhoea (294). Most-referenced drug: Milbemycin Oxime + Spinosad (572 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (298) and Afoxolaner (230).

Outcome coding on 2,880 status-recorded reports is dominated by Recovered/Normal (35.9%). Annual submissions ranged 12-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Terrier - Rat
3,078 reports · 4.3% death-coded
Lhasa Apso
3,196 reports · 3.7% death-coded
Spaniel (unspecified)
3,209 reports · 4.8% death-coded
Mountain Dog - Bernese
3,012 reports · 4.2% death-coded
Mastiff
2,950 reports · 6.2% death-coded
Corgi (unspecified)
2,865 reports · 4.2% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Collie (unspecified) drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (4.8% death-coded here).

Scottish Fold Longhair 4.8% · Cat Bengal 4.6% · Cat Egyptian Mau 5.3% · Cat Siberian 4.2% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (25.9 kg here).

Mixed (Sheep) 24.9 kg · Sheep Crossbred Caprine/goat 21.7 kg · Goat Pygmy 20.3 kg · Goat Fish (other) 32.4 kg · Fish

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Collie (unspecified)? ▼
There are 3,131 adverse event reports involving Collie (unspecified) in the FDA database, of which 149 were death-coded (4.8% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Collie (unspecified) ranks #60 of 510 by report volume among all breeds PlainBreed indexes (#53 of 298 among dog breeds).
Where does Collie (unspecified) sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Collie (unspecified) is #60 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #53 of 298. Among breeds with at least 50 reports, its death-coded share ranks #142 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Collie (unspecified)? ▼
The most commonly reported adverse reactions for Collie (unspecified) are Vomiting (544 reports), Emesis (342 reports), Diarrhoea (294 reports), Lethargy (see also Central nervous system depression in 'Neurological') (265 reports), Lack of efficacy (endoparasite) - heartworm (185 reports).
What drugs are most frequently associated with Collie (unspecified) adverse events? ▼
The drugs most frequently referenced in Collie (unspecified) adverse event reports are Milbemycin Oxime + Spinosad (572 reports), Ivermectin + Pyrantel As Pamoate Salt (298 reports), Afoxolaner (230 reports), Spinosad (209 reports), Pyrantel Pamoate;Sarolaner (164 reports).
What is the average age of Collie (unspecified) in adverse event reports? ▼
The average age of Collie (unspecified) at the time of adverse event reports is 5.8 years, with an average weight of 25.9 kg (57.1 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Collie (unspecified) (Dog), extract as of July 2026 extract. 3,131 reports · 149 death-coded (4.8% of reports, not a mortality rate) · #60 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →