Total Reports
15,583
FDA CVM filings
Dog /
FDA CVM · 2025 release 15,583 reports on file
Shepherd Dog - Australian - FDA Adverse Event Profile
Adverse-event records for Shepherd Dog - Australian (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Shepherd Dog - Australian's FDA record: #13 most-reported dog breed, 15,583 total reports, 3.7% death-coded (574 reports).
- #13
- most-reported dog breed
- 3.7%
- death-coded report share
- 3,458
- Vomiting - top reaction
- 4.5 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
574
of 15,583 reports
Death Rate
3.7%
death-coded share
Avg Age at Report
4.5 yr
19.9 kg avg weight
Death-Coded Outcome Share
Shepherd Dog - Australian death-coded reports 3.7%
Cross-breed median
3.7% of 15,583 shepherd dog - australian reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 19.9 kg (43.9 lbs)
Top Reported Reactions
Vomiting 3,458
Lethargy (see also Central nervous system depression in 'Neurological') 1,215
Emesis 1,194
Lack of efficacy (endoparasite) - heartworm 1,155
Diarrhoea 1,148
Lack of efficacy (endoparasite) - hookworm 834
Seizure NOS 773
Lack of efficacy (ectoparasite) - flea 718
Lack of efficacy - NOS 634
INEFFECTIVE, HEARTWORM LARVAE 606
Lack of efficacy (ectoparasite) - tick NOS 499
Lack of efficacy (bacteria) - Borrelia 437
Anorexia 404
Lack of efficacy (endoparasite) - roundworm NOS 399
Ataxia 358
Most Referenced Drugs
Milbemycin Oxime + Spinosad 2,924
Ivermectin + Pyrantel As Pamoate Salt 1,769
Pyrantel Pamoate;Sarolaner 1,517
Afoxolaner 1,295
Milbemycin Oxime + Praziquantel 1,075
Moxidectin 953
Fluralaner 13.64% 12-Week Chew 636
Fluralaner Chew Tablets 620
Spinosad 595
Sarolaner 402
Bedinvetmab 397
Carprofen 395
Lotilaner 383
Oclacitinib Maleate 319
Milbemycin Oxime 227
Outcome Breakdown
Recovered/Normal
5,134 (34.3%)
Outcome Unknown
4,619 (30.9%)
Ongoing
4,153 (27.8%)
Recovered with Sequela
478 (3.2%)
Died
297 (2.0%)
Euthanized
277 (1.9%)
Gender Distribution
Female 7,747 (49.7%)
Male 7,510 (48.2%)
Unknown 274 (1.8%)
Mixed 52 (0.3%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 354 | |
| 2011 | 383 | |
| 2012 | 747 | |
| 2013 | 850 | |
| 2014 | 847 | |
| 2015 | 926 | |
| 2016 | 913 | |
| 2017 | 1,046 | |
| 2018 | 1,007 | |
| 2019 | 1,110 | |
| 2020 | 1,191 | |
| 2021 | 1,145 | |
| 2022 | 1,220 | |
| 2023 | 1,322 | |
| 2024 | 1,492 | |
| 2025 | 1,030 | |
Shepherd Dog - Australian Pet Health Insights
Shepherd Dog - Australian accounts for 15,583 FDA adverse event reports, ranking #13 by volume among dog breeds, with 574 reports (3.7%) coded as a death outcome. Mean age at report: 4.5 years, average weight 19.9 kg (43.9 lbs).
Top reported signs: Vomiting (3,458), Lethargy (see also Central nervous system depression in 'Neurological') (1,215), Emesis (1,194). Most-referenced drug: Milbemycin Oxime + Spinosad (2,924 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (1,769) and Pyrantel Pamoate;Sarolaner (1,517).
Outcome coding on 14,958 status-recorded reports is dominated by Recovered/Normal (34.3%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Shepherd Dog - Australian? ▼
There are 15,583 adverse event reports involving Shepherd Dog - Australian in the FDA database, with 574 reports involving death (3.7% death rate). Shepherd Dog - Australian ranks #13 by report volume.
What are the most common adverse reactions reported for Shepherd Dog - Australian? ▼
The most commonly reported adverse reactions for Shepherd Dog - Australian are Vomiting (3,458 reports), Lethargy (see also Central nervous system depression in 'Neurological') (1,215 reports), Emesis (1,194 reports), Lack of efficacy (endoparasite) - heartworm (1,155 reports), Diarrhoea (1,148 reports).
What drugs are most frequently associated with Shepherd Dog - Australian adverse events? ▼
The drugs most frequently referenced in Shepherd Dog - Australian adverse event reports are Milbemycin Oxime + Spinosad (2,924 reports), Ivermectin + Pyrantel As Pamoate Salt (1,769 reports), Pyrantel Pamoate;Sarolaner (1,517 reports), Afoxolaner (1,295 reports), Milbemycin Oxime + Praziquantel (1,075 reports).
What is the average age of Shepherd Dog - Australian in adverse event reports? ▼
The average age of Shepherd Dog - Australian at the time of adverse event reports is 4.5 years, with an average weight of 19.9 kg (43.9 lbs).
Does a high number of adverse event reports mean Shepherd Dog - Australian is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Shepherd Dog - Australian safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.