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Breed profile · FDA CVM July 2026 extract

Retriever - Labrador adverse-event record

Adverse-event filings for Retriever - Labrador (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#1 of 510
by report volume (all breeds)
93,675
FDA CVM reports on file
3.7%
death-coded share of reports
#195 of 275
by death-coded share (≥50 reports)

How the 93,675 reports break down

By recorded gender -- every report on file for Retriever - Labrador, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 6,680 5,010 3,340 1,670 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Retriever - Labrador drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Retriever - Labrador is #1 of 510 by total reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#1
This breed, reports of 510
#195
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Retriever - Labrador has 93,675 reports now versus 92,460 in that prior snapshot: 1,215 more (1.3%).

Report change
+1,215
Death-coded reports
+47
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Retriever - Labrador changes

Total Reports

93,675

Highest-reported breed

Deaths Reported

3,463

of 93,675 reports

Death-coded share of reports

3.7%

Below-median death-coded share

Avg Age at Report

5.2 yr

30.8 kg avg weight

Breed Safety Scorecard

C (58/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate B
3.7%

Share of reports coded as a fatality

Euthanasia rate C+
1.9%

Share of reports resulting in euthanasia

Full recovery rate F
25.9%

Share of reports coded "Recovered/Normal"

5-year trend C-
+4%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Retriever - Labrador death-coded reports 3.7%
Cross-breed median

3.7% of 93,675 retriever - labrador reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Retriever - Labrador's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

4% 29th percentile Higher share than 29% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Retriever - Labrador 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Retriever - Labrador among report-volume vs. death-rate peers

Every breed shown has at least 50 filed reports. Volume reflects how often a breed is reported, not how common it is; death rate is the share of a breed's own reports coded as a death outcome.

Source: FDA openFDA Animal & Veterinary Adverse Events database 2×2 strategic matrix plotting 30 entities by Total Reports (X) and Death Rate (%) (Y), with a crosshair dividing the plot into four quadrants. High volume, high death rateLow volume, high death rateHigh volume, low death rateLow volume, low death rate 020,00040,00060,00080,000100,000 0%5%10%15% Total Reports Death Rate (%) Retriever - Labrador vs. all breeds, report volume and death-coded share Retriever - Labrador-93675, 3.7%Crossbred Canine/dog-70591, 3.2%Domestic Shorthair-65226, 7.2%Dog (unknown)-48820, 8.8%Retriever - Golden-35980, 3.7%Shepherd Dog - German-32220, 4.4%Chihuahua-31521, 4.2%Terrier - Yorkshire-24924, 3.7%Shih Tzu-24405, 3.6%Boxer (German Boxer)-19405, 4.4%Beagle-17970, 3.6%Pit Bull-17865, 3.1%Shepherd Dog - Australian-16274, 3.7%Terrier (unspecified)-14058, 3.1%Maltese-13940, 3.2%Dachshund (unspecified)-13512, 4.6%Cat (unknown)-13248, 9.3%Terrier - Jack Russell-10423, 3.7%Collie - Border-10130, 4.3%Siberian Husky-9811, 4.5%Domestic Longhair-9615, 7%Pug-9224, 5.2%Spitz - German Pomeranian-9086, 4.9%Terrier - Bull - American Pit-8769, 4.7%Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)-7871, 3.6%Terrier - Boston-7737, 4.5%Spaniel - Cocker American-7640, 4%Domestic (unspecified)-7576, 13.4%Poodle (unspecified)-7534, 3.4%Schnauzer - Miniature-7513, 4.4%
Source: FDA openFDA Animal & Veterinary Adverse Events database
Average weight at time of report: 30.8 kg (67.9 lbs)

Top Reported Reactions

Vomiting 15,717
Lack of efficacy (endoparasite) - heartworm 10,620
INEFFECTIVE, HEARTWORM LARVAE 9,664
Emesis 6,720
Lack of efficacy (endoparasite) - hookworm 5,987
Lack of efficacy - NOS 5,895
Lethargy (see also Central nervous system depression in 'Neurological') 5,869
Diarrhoea 5,730
Digestive tract disorder NOS 3,656
Seizure NOS 2,979
Anorexia 2,967
Cardiac disorder NOS 2,756
INEFFECTIVE, ASCARIDS NOS 2,558
Elevated alanine aminotransferase (ALT) 2,544
Lack of efficacy (ectoparasite) - flea 2,483

Most Referenced Drugs

Milbemycin Oxime + Spinosad 16,527
Ivermectin + Pyrantel As Pamoate Salt 14,916
Pyrantel Pamoate;Sarolaner 5,981
Moxidectin 5,785
Milbemycin Oxime + Praziquantel 5,518
Afoxolaner 5,494
Carprofen 4,429
Bedinvetmab 3,164
Oclacitinib Maleate 2,996
Spinosad 2,961
Fluralaner Chew Tablets 2,581
Fluralaner 13.64% 12-Week Chew 1,957
Ivermectin, Pyrantel 1,771
Sarolaner 1,701
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 1,601

Outcome Breakdown

Outcome Unknown
29,945 (34.3%)
Recovered/Normal
24,298 (27.9%)
Ongoing
24,110 (27.6%)
Recovered with Sequela
5,377 (6.2%)
Euthanized
1,788 (2.1%)
Died
1,681 (1.9%)

Gender Distribution

Male 46,193 (49.3%)
Female 46,078 (49.2%)
Unknown 1,190 (1.3%)
Mixed 214 (0.2%)

Reports by Year

Year Reports Trend
2010 3,617
2011 3,906
2012 5,248
2013 5,940
2014 6,189
2015 6,509
2016 6,916
2017 6,945
2018 6,559
2019 6,435
2020 5,958
2021 5,586
2022 5,129
2023 5,339
2024 6,680
2025 5,810
2026 909

Retriever - Labrador: low death-coded share in the FDA CVM extract

Signature read: 93,675 reports place Retriever - Labrador in the upper third of breed filing volume (#1 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Retriever - Labrador sits at #1 of 510 by report volume among all breeds and #1 of 298 among dog breeds, with 93,675 reports and 3,463 (3.7%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #195 of 275. Mean age at report: 5.2 years, average weight 30.8 kg (67.9 lbs).

Top reported signs: Vomiting (15,717), Lack of efficacy (endoparasite) - heartworm (10,620), INEFFECTIVE, HEARTWORM LARVAE (9,664). Most-referenced drug: Milbemycin Oxime + Spinosad (16,527 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (14,916) and Pyrantel Pamoate;Sarolaner (5,981).

Outcome coding on 87,199 status-recorded reports is dominated by Outcome Unknown (34.3%). Annual submissions ranged 909-2,026 across 17 years on file.

Retriever - Labrador Reporting Concentration Profile

Retriever - Labrador is a high-volume FDA CVM cohort (93,675 reports) - enough filings to measure how concentrated the reaction and drug mix is, not just the headline totals. Across 20 named reaction terms in the stored top list, the leading three (Vomiting, Lack of efficacy (endoparasite) - heartworm, INEFFECTIVE, HEARTWORM LARVAE) account for 37.3% of listed reaction mentions. The Herfindahl index on that list is 0.077 (1.0 = a single reaction owns every mention; lower = a broader clinical mix).

On the drug side, 20 referenced products appear in the top list; the leading three (Milbemycin Oxime + Spinosad, Ivermectin + Pyrantel As Pamoate Salt, Pyrantel Pamoate;Sarolaner) cover 44.4% of those mentions. That multi-product footprint is the profile thin-report breeds cannot show - their pages stop at a short bar list because the sample cannot support a concentration read.

Outcome coding on 87,199 status-recorded filings splits roughly 4.0% severe (died or euthanized - 3,469 reports) versus 34.0% recovered or recovered-with-sequela (29,675). Read that split next to the 3.7% death-coded share above - both track reporting severity bias in a popular breed, not a proven mortality rate.

Peak filing year was 2017 (6,945 reports); the lightest year on file was 2026 (909). From 2024 to 2025, annual volume fell 13.0% (6,680 → 5,810). Year-to-year swings at this volume usually track product launches, owner awareness, and reporting campaigns more than sudden breed-health shocks.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Crossbred Canine/dog
70,591 reports · 3.2% death-coded
Dog (unknown)
48,820 reports · 8.8% death-coded
Retriever - Golden
35,980 reports · 3.7% death-coded
Shepherd Dog - German
32,220 reports · 4.4% death-coded
Chihuahua
31,521 reports · 4.2% death-coded
Terrier - Yorkshire
24,924 reports · 3.7% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Retriever - Labrador drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (3.7% death-coded here).

British cat 3.8% · Cat American Curl Shorthair 3.5% · Cat Siberian 4.2% · Cat Oriental 3.1% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (30.8 kg here).

Fish (other) 32.4 kg · Fish Katahdin 32.4 kg · Sheep Nubian 32.8 kg · Goat Goat (unknown) 35.9 kg · Goat

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Retriever - Labrador? ▼
There are 93,675 adverse event reports involving Retriever - Labrador in the FDA database, of which 3,463 were death-coded (3.7% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Retriever - Labrador ranks #1 of 510 by report volume among all breeds PlainBreed indexes (#1 of 298 among dog breeds).
Where does Retriever - Labrador sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Retriever - Labrador is #1 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #1 of 298. Among breeds with at least 50 reports, its death-coded share ranks #195 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Retriever - Labrador? ▼
The most commonly reported adverse reactions for Retriever - Labrador are Vomiting (15,717 reports), Lack of efficacy (endoparasite) - heartworm (10,620 reports), INEFFECTIVE, HEARTWORM LARVAE (9,664 reports), Emesis (6,720 reports), Lack of efficacy (endoparasite) - hookworm (5,987 reports).
What drugs are most frequently associated with Retriever - Labrador adverse events? ▼
The drugs most frequently referenced in Retriever - Labrador adverse event reports are Milbemycin Oxime + Spinosad (16,527 reports), Ivermectin + Pyrantel As Pamoate Salt (14,916 reports), Pyrantel Pamoate;Sarolaner (5,981 reports), Moxidectin (5,785 reports), Milbemycin Oxime + Praziquantel (5,518 reports).
What is the average age of Retriever - Labrador in adverse event reports? ▼
The average age of Retriever - Labrador at the time of adverse event reports is 5.2 years, with an average weight of 30.8 kg (67.9 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Retriever - Labrador (Dog), extract as of July 2026 extract. 93,675 reports · 3,463 death-coded (3.7% of reports, not a mortality rate) · #1 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →