Total Reports
9,399
FDA CVM filings
Dog /
FDA CVM · 2025 release 9,399 reports on file
Siberian Husky - FDA Adverse Event Profile
Adverse-event records for Siberian Husky (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Siberian Husky's FDA record: #20 most-reported dog breed, 9,399 total reports, 4.4% death-coded (418 reports).
- #20
- most-reported dog breed
- 4.4%
- death-coded report share
- 1,818
- Vomiting - top reaction
- 4.8 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
418
of 9,399 reports
Death Rate
4.4%
death-coded share
Avg Age at Report
4.8 yr
25.3 kg avg weight
Death-Coded Outcome Share
Siberian Husky death-coded reports 4.4%
Cross-breed median
4.4% of 9,399 siberian husky reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 25.3 kg (55.8 lbs)
Top Reported Reactions
Vomiting 1,818
Lack of efficacy (endoparasite) - heartworm 805
Lethargy (see also Central nervous system depression in 'Neurological') 788
Diarrhoea 735
Emesis 671
Seizure NOS 556
INEFFECTIVE, HEARTWORM LARVAE 454
Lack of efficacy (ectoparasite) - flea 450
Lack of efficacy - NOS 431
Lack of efficacy (endoparasite) - hookworm 387
Anorexia 292
Ataxia 250
Lack of efficacy (bacteria) - Borrelia 247
Lack of efficacy (ectoparasite) - tick NOS 243
Digestive tract disorder NOS 236
Most Referenced Drugs
Milbemycin Oxime + Spinosad 1,733
Ivermectin + Pyrantel As Pamoate Salt 1,060
Pyrantel Pamoate;Sarolaner 811
Moxidectin 699
Afoxolaner 606
Milbemycin Oxime + Praziquantel 489
Spinosad 407
Sarolaner 343
Fluralaner Chew Tablets 338
Fluralaner 13.64% 12-Week Chew 312
Carprofen 301
Bedinvetmab 297
Trilostane 155
Melarsomine Dihydrochloride 153
Oclacitinib Maleate 153
Outcome Breakdown
Outcome Unknown
2,894 (32.1%)
Recovered/Normal
2,829 (31.4%)
Ongoing
2,546 (28.3%)
Recovered with Sequela
315 (3.5%)
Died
235 (2.6%)
Euthanized
183 (2.0%)
Gender Distribution
Female 4,802 (51.1%)
Male 4,396 (46.8%)
Unknown 177 (1.9%)
Mixed 24 (0.3%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 224 | |
| 2011 | 286 | |
| 2012 | 474 | |
| 2013 | 469 | |
| 2014 | 546 | |
| 2015 | 559 | |
| 2016 | 605 | |
| 2017 | 666 | |
| 2018 | 678 | |
| 2019 | 736 | |
| 2020 | 744 | |
| 2021 | 636 | |
| 2022 | 679 | |
| 2023 | 752 | |
| 2024 | 824 | |
| 2025 | 521 | |
Siberian Husky Pet Health Insights
Siberian Husky accounts for 9,399 FDA adverse event reports, ranking #20 by volume among dog breeds, with 418 reports (4.4%) coded as a death outcome. Mean age at report: 4.8 years, average weight 25.3 kg (55.8 lbs).
Top reported signs: Vomiting (1,818), Lack of efficacy (endoparasite) - heartworm (805), Lethargy (see also Central nervous system depression in 'Neurological') (788). Most-referenced drug: Milbemycin Oxime + Spinosad (1,733 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (1,060) and Pyrantel Pamoate;Sarolaner (811).
Outcome coding on 9,002 status-recorded reports is dominated by Outcome Unknown (32.1%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Pug
9,020 reports · 5.1% death rate
Collie - Border
9,801 reports · 4.3% death rate
Spitz - German Pomeranian
8,853 reports · 5.0% death rate
Terrier - Jack Russell
10,210 reports · 3.7% death rate
Terrier - Bull - American Pit
8,232 reports · 4.5% death rate
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)
7,541 reports · 3.6% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Siberian Husky? ▼
There are 9,399 adverse event reports involving Siberian Husky in the FDA database, with 418 reports involving death (4.4% death rate). Siberian Husky ranks #20 by report volume.
What are the most common adverse reactions reported for Siberian Husky? ▼
The most commonly reported adverse reactions for Siberian Husky are Vomiting (1,818 reports), Lack of efficacy (endoparasite) - heartworm (805 reports), Lethargy (see also Central nervous system depression in 'Neurological') (788 reports), Diarrhoea (735 reports), Emesis (671 reports).
What drugs are most frequently associated with Siberian Husky adverse events? ▼
The drugs most frequently referenced in Siberian Husky adverse event reports are Milbemycin Oxime + Spinosad (1,733 reports), Ivermectin + Pyrantel As Pamoate Salt (1,060 reports), Pyrantel Pamoate;Sarolaner (811 reports), Moxidectin (699 reports), Afoxolaner (606 reports).
What is the average age of Siberian Husky in adverse event reports? ▼
The average age of Siberian Husky at the time of adverse event reports is 4.8 years, with an average weight of 25.3 kg (55.8 lbs).
Does a high number of adverse event reports mean Siberian Husky is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Siberian Husky safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.