Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
7,559
Total Reports
1,012
Deaths Reported
1340.0%
Death Rate
6.5 yr
Avg Age at Report
Average weight at time of report: 4.8 kg (10.6 lbs)
Top Reported Reactions
Depression 1,233
Vomiting 1,202
Anorexia 1,149
Application site alopecia 942
Death 561
Hypersalivation 516
Ataxia 460
Death by euthanasia 436
Diarrhoea 372
Elevated blood urea nitrogen (BUN) 359
Fever 318
Application site lesion 307
Lack of efficacy (ectoparasite) - flea 307
Elevated creatinine 305
Weight loss 289
Most Referenced Drugs
Selamectin 1,991
Cefovecin Sodium 752
Spinosad 483
Human Insulin 453
Nitenpyram 446
Meloxicam 442
Imidacloprid, Moxidectin 390
Emodepside, Praziquantel 263
Cyclosporine 229
Ketamine Hydrochloride 190
Dexmedetomidine Hydrochloride 157
Amoxicillin, Clavulanate 136
Orbifloxacin 133
Maropitant 127
Methylprednisolone Acetate 105
Outcome Breakdown
Died
999 (59.1%)
Recovered/Normal
308 (18.2%)
Outcome Unknown
264 (15.6%)
Ongoing
93 (5.5%)
Euthanized
13 (0.8%)
Recovered with Sequela
12 (0.7%)
Gender Distribution
Male 3,885 (51.4%)
Female 3,338 (44.2%)
Unknown 186 (2.5%)
Mixed 150 (2.0%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 3,309 | |
| 2011 | 2,343 | |
| 2012 | 1,083 | |
| 2013 | 178 | |
| 2014 | 127 | |
| 2015 | 81 | |
| 2016 | 53 | |
| 2017 | 43 | |
| 2018 | 39 | |
| 2019 | 32 | |
| 2020 | 45 | |
| 2021 | 46 | |
| 2022 | 49 | |
| 2023 | 36 | |
| 2024 | 57 | |
| 2025 | 38 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #25 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.