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2026 FDA CVM data 3,013 reports on file official source

Terrier - Rat — FDA Adverse Event Profile

Adverse-event records and label data for Terrier - Rat (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 218 163.5 109 54.5 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Terrier - Rat drawn from FDA CVM filings.

Terrier - Rat (Dog) has 3,013 FDA adverse event reports on record, with 131 deaths reported (430.0% death rate) — ranking #61 by report volume. The most frequently reported reaction is Vomiting (614 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 6.7 years.

Total Reports

3,013

FDA CVM filings

Deaths Reported

131

of 3,013 reports

Death Rate

430.0%

death-coded share

Avg Age at Report

6.7 yr

7.9 kg avg weight

Death-Coded Outcome Share

Terrier - Rat death-coded reports 100.0%
Database median

430.0% of 3,013 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 7.9 kg (17.4 lbs)

Top Reported Reactions

Vomiting 614
Lethargy (see also Central nervous system depression in 'Neurological') 290
INEFFECTIVE, HEARTWORM LARVAE 270
Emesis 263
Lack of efficacy (ectoparasite) - flea 249
Lack of efficacy - NOS 215
Lack of efficacy (endoparasite) - heartworm 208
Diarrhoea 155
Seizure NOS 131
Lack of efficacy (endoparasite) - hookworm 127
Anorexia 103
Cardiac disorder NOS 91
Ataxia 82
Pruritus 79
Shaking 76

Most Referenced Drugs

Milbemycin Oxime + Spinosad 686
Ivermectin + Pyrantel As Pamoate Salt 353
Spinosad 289
Moxidectin 206
Afoxolaner 194
Trilostane 115
Pyrantel Pamoate;Sarolaner 114
Oclacitinib Maleate 112
Milbemycin Oxime + Praziquantel 96
Imidacloprid + Moxidectin 63
Ivermectin, Pyrantel 59
Sarolaner 59
Carprofen 56
Melarsomine Dihydrochloride 51
Maropitant Citrate 49

Outcome Breakdown

Outcome Unknown
1,007 (36.4%)
Recovered/Normal
845 (30.6%)
Ongoing
585 (21.2%)
Recovered with Sequela
195 (7.1%)
Euthanized
66 (2.4%)
Died
65 (2.4%)

Gender Distribution

Female 1,619 (53.7%)
Male 1,337 (44.4%)
Unknown 49 (1.6%)
Mixed 8 (0.3%)

Reports by Year

Year Reports Trend
2010 136
2011 184
2012 228
2013 279
2014 239
2015 229
2016 226
2017 261
2018 201
2019 218
2020 174
2021 121
2022 118
2023 151
2024 148
2025 100
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Terrier - Rat sits in the registered size-class taxonomy. Average reported weight: 7.9 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Terrier - Rat Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Terrier - Rat accounts for 3,013 submitted reports and currently ranks #61 by report volume within the dog population. Of those reports, 131 involved a death outcome — a 430.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 6.7 years, with an average recorded body weight of 7.9 kg (17.4 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Terrier - Rat are Vomiting (614 reports), Lethargy (see also Central nervous system depression in 'Neurological') (290 reports), INEFFECTIVE, HEARTWORM LARVAE (270 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 686 reports and is the single most-referenced drug, followed by Ivermectin + Pyrantel As Pamoate Salt (353) and Spinosad (289). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 2,763 reports with a recorded status is dominated by Outcome Unknown (36.4% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Terrier - Rat Adverse Event Data

Terrier - Rat has a moderate volume of adverse event reports (3,013). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 430.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 686 reports. This may indicate widespread use of the medication rather than a specific safety concern for Terrier - Rat.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Terrier - Rat?
There are 3,013 adverse event reports involving Terrier - Rat in the FDA database, with 131 reports involving death (430.0% death rate). Terrier - Rat ranks #61 by report volume.
What are the most common adverse reactions reported for Terrier - Rat?
The most commonly reported adverse reactions for Terrier - Rat are Vomiting (614 reports), Lethargy (see also Central nervous system depression in 'Neurological') (290 reports), INEFFECTIVE, HEARTWORM LARVAE (270 reports), Emesis (263 reports), Lack of efficacy (ectoparasite) - flea (249 reports).
What drugs are most frequently associated with Terrier - Rat adverse events?
The drugs most frequently referenced in Terrier - Rat adverse event reports are Milbemycin Oxime + Spinosad (686 reports), Ivermectin + Pyrantel As Pamoate Salt (353 reports), Spinosad (289 reports), Moxidectin (206 reports), Afoxolaner (194 reports).
What is the average age of Terrier - Rat in adverse event reports?
The average age of Terrier - Rat at the time of adverse event reports is 6.7 years, with an average weight of 7.9 kg (17.4 lbs).
Does a high number of adverse event reports mean Terrier - Rat is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Rat safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Terrier - Rat ranks #61 by total report volume. Death rate (430.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial