Total Reports
1,928
FDA CVM filings
Dog /
FDA CVM · 2025 release 1,928 reports on file
Terrier - Cairn - FDA Adverse Event Profile
Adverse-event records for Terrier - Cairn (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 1,928 reports on file, Terrier - Cairn sits at #81 among dog breeds by volume; death-coded share is 4.7% (90 reports).
- #81
- most-reported dog breed
- 4.7%
- death-coded report share
- 429
- Vomiting - top reaction
- 7.5 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
90
of 1,928 reports
Death Rate
4.7%
death-coded share
Avg Age at Report
7.5 yr
8.5 kg avg weight
Death-Coded Outcome Share
Terrier - Cairn death-coded reports 4.7%
Cross-breed median
4.7% of 1,928 terrier - cairn reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 8.5 kg (18.7 lbs)
Top Reported Reactions
Vomiting 429
Lethargy (see also Central nervous system depression in 'Neurological') 225
Emesis 207
Diarrhoea 148
Lack of efficacy - NOS 118
Lack of efficacy (ectoparasite) - flea 107
Lack of efficacy (endoparasite) - hookworm 94
Anorexia 84
Seizure NOS 69
Other abnormal test result NOS 68
Behavioural disorder NOS 67
Elevated serum alkaline phosphatase (SAP) 66
INEFFECTIVE, HEARTWORM LARVAE 58
Elevated alanine aminotransferase (ALT) 57
INEFFECTIVE, ASCARIDS NOS 56
Most Referenced Drugs
Milbemycin Oxime + Spinosad 378
Ivermectin + Pyrantel As Pamoate Salt 146
Spinosad 144
Afoxolaner 123
Oclacitinib Maleate 114
Fluralaner Chew Tablets 101
Pyrantel Pamoate;Sarolaner 74
Moxidectin 61
Trilostane 58
Sarolaner 48
Cyclosporine 46
Milbemycin Oxime + Praziquantel 44
Fluralaner 13.64% 12-Week Chew 43
Selamectin 38
Bedinvetmab 38
Outcome Breakdown
Recovered/Normal
667 (38.4%)
Outcome Unknown
499 (28.7%)
Ongoing
408 (23.5%)
Recovered with Sequela
73 (4.2%)
Euthanized
49 (2.8%)
Died
41 (2.4%)
Gender Distribution
Male 968 (50.2%)
Female 929 (48.2%)
Unknown 26 (1.3%)
Mixed 5 (0.3%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 98 | |
| 2011 | 116 | |
| 2012 | 184 | |
| 2013 | 159 | |
| 2014 | 179 | |
| 2015 | 173 | |
| 2016 | 155 | |
| 2017 | 158 | |
| 2018 | 129 | |
| 2019 | 118 | |
| 2020 | 96 | |
| 2021 | 79 | |
| 2022 | 77 | |
| 2023 | 74 | |
| 2024 | 83 | |
| 2025 | 50 | |
Terrier - Cairn Pet Health Insights
Terrier - Cairn accounts for 1,928 FDA adverse event reports, ranking #81 by volume among dog breeds, with 90 reports (4.7%) coded as a death outcome. Mean age at report: 7.5 years, average weight 8.5 kg (18.7 lbs).
Top reported signs: Vomiting (429), Lethargy (see also Central nervous system depression in 'Neurological') (225), Emesis (207). Most-referenced drug: Milbemycin Oxime + Spinosad (378 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (146) and Spinosad (144).
Outcome coding on 1,737 status-recorded reports is dominated by Recovered/Normal (38.4%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Brittany
1,837 reports · 2.7% death rate
Chow Chow
2,029 reports · 6.4% death rate
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne))
2,087 reports · 4.4% death rate
Spaniel - Springer English
2,187 reports · 3.9% death rate
Shepherd Dog - Belgian Malinois
1,623 reports · 3.0% death rate
Shiba Inu
1,622 reports · 2.5% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Terrier - Cairn? ▼
There are 1,928 adverse event reports involving Terrier - Cairn in the FDA database, with 90 reports involving death (4.7% death rate). Terrier - Cairn ranks #81 by report volume.
What are the most common adverse reactions reported for Terrier - Cairn? ▼
The most commonly reported adverse reactions for Terrier - Cairn are Vomiting (429 reports), Lethargy (see also Central nervous system depression in 'Neurological') (225 reports), Emesis (207 reports), Diarrhoea (148 reports), Lack of efficacy - NOS (118 reports).
What drugs are most frequently associated with Terrier - Cairn adverse events? ▼
The drugs most frequently referenced in Terrier - Cairn adverse event reports are Milbemycin Oxime + Spinosad (378 reports), Ivermectin + Pyrantel As Pamoate Salt (146 reports), Spinosad (144 reports), Afoxolaner (123 reports), Oclacitinib Maleate (114 reports).
What is the average age of Terrier - Cairn in adverse event reports? ▼
The average age of Terrier - Cairn at the time of adverse event reports is 7.5 years, with an average weight of 8.5 kg (18.7 lbs).
Does a high number of adverse event reports mean Terrier - Cairn is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Cairn safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.