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2026 FDA CVM data 1,928 reports on file official source

Terrier - Cairn — FDA Adverse Event Profile

Adverse-event records and label data for Terrier - Cairn (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 129 96.75 64.5 32.25 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Terrier - Cairn drawn from FDA CVM filings.

Terrier - Cairn (Dog) has 1,928 FDA adverse event reports on record, with 90 deaths reported (470.0% death rate) — ranking #81 by report volume. The most frequently reported reaction is Vomiting (429 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 7.5 years.

Total Reports

1,928

FDA CVM filings

Deaths Reported

90

of 1,928 reports

Death Rate

470.0%

death-coded share

Avg Age at Report

7.5 yr

8.5 kg avg weight

Death-Coded Outcome Share

Terrier - Cairn death-coded reports 100.0%
Database median

470.0% of 1,928 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 8.5 kg (18.7 lbs)

Top Reported Reactions

Vomiting 429
Lethargy (see also Central nervous system depression in 'Neurological') 225
Emesis 207
Diarrhoea 148
Lack of efficacy - NOS 118
Lack of efficacy (ectoparasite) - flea 107
Lack of efficacy (endoparasite) - hookworm 94
Anorexia 84
Seizure NOS 69
Other abnormal test result NOS 68
Behavioural disorder NOS 67
Elevated serum alkaline phosphatase (SAP) 66
INEFFECTIVE, HEARTWORM LARVAE 58
Elevated alanine aminotransferase (ALT) 57
INEFFECTIVE, ASCARIDS NOS 56

Most Referenced Drugs

Milbemycin Oxime + Spinosad 378
Ivermectin + Pyrantel As Pamoate Salt 146
Spinosad 144
Afoxolaner 123
Oclacitinib Maleate 114
Fluralaner Chew Tablets 101
Pyrantel Pamoate;Sarolaner 74
Moxidectin 61
Trilostane 58
Sarolaner 48
Cyclosporine 46
Milbemycin Oxime + Praziquantel 44
Fluralaner 13.64% 12-Week Chew 43
Selamectin 38
Bedinvetmab 38

Outcome Breakdown

Recovered/Normal
667 (38.4%)
Outcome Unknown
499 (28.7%)
Ongoing
408 (23.5%)
Recovered with Sequela
73 (4.2%)
Euthanized
49 (2.8%)
Died
41 (2.4%)

Gender Distribution

Male 968 (50.2%)
Female 929 (48.2%)
Unknown 26 (1.3%)
Mixed 5 (0.3%)

Reports by Year

Year Reports Trend
2010 98
2011 116
2012 184
2013 159
2014 179
2015 173
2016 155
2017 158
2018 129
2019 118
2020 96
2021 79
2022 77
2023 74
2024 83
2025 50
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Terrier - Cairn sits in the registered size-class taxonomy. Average reported weight: 8.5 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Terrier - Cairn Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Terrier - Cairn accounts for 1,928 submitted reports and currently ranks #81 by report volume within the dog population. Of those reports, 90 involved a death outcome — a 470.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 7.5 years, with an average recorded body weight of 8.5 kg (18.7 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Terrier - Cairn are Vomiting (429 reports), Lethargy (see also Central nervous system depression in 'Neurological') (225 reports), Emesis (207 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 378 reports and is the single most-referenced drug, followed by Ivermectin + Pyrantel As Pamoate Salt (146) and Spinosad (144). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 1,737 reports with a recorded status is dominated by Recovered/Normal (38.4% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Terrier - Cairn Adverse Event Data

Terrier - Cairn has a moderate volume of adverse event reports (1,928). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 470.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 378 reports. This may indicate widespread use of the medication rather than a specific safety concern for Terrier - Cairn.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Terrier - Cairn?
There are 1,928 adverse event reports involving Terrier - Cairn in the FDA database, with 90 reports involving death (470.0% death rate). Terrier - Cairn ranks #81 by report volume.
What are the most common adverse reactions reported for Terrier - Cairn?
The most commonly reported adverse reactions for Terrier - Cairn are Vomiting (429 reports), Lethargy (see also Central nervous system depression in 'Neurological') (225 reports), Emesis (207 reports), Diarrhoea (148 reports), Lack of efficacy - NOS (118 reports).
What drugs are most frequently associated with Terrier - Cairn adverse events?
The drugs most frequently referenced in Terrier - Cairn adverse event reports are Milbemycin Oxime + Spinosad (378 reports), Ivermectin + Pyrantel As Pamoate Salt (146 reports), Spinosad (144 reports), Afoxolaner (123 reports), Oclacitinib Maleate (114 reports).
What is the average age of Terrier - Cairn in adverse event reports?
The average age of Terrier - Cairn at the time of adverse event reports is 7.5 years, with an average weight of 8.5 kg (18.7 lbs).
Does a high number of adverse event reports mean Terrier - Cairn is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Cairn safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Terrier - Cairn ranks #81 by total report volume. Death rate (470.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial