Total Reports
1,261
FDA CVM filings
Dog /
FDA CVM · 2025 release 1,261 reports on file
Newfoundland - FDA Adverse Event Profile
Adverse-event records for Newfoundland (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Newfoundland is #96 by FDA report volume; 7.2% of its 1,261 reports (91) were death-coded.
- #96
- most-reported dog breed
- 7.2%
- death-coded report share
- 216
- Vomiting - top reaction
- 4.8 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
91
of 1,261 reports
Death Rate
7.2%
death-coded share
Avg Age at Report
4.8 yr
49.0 kg avg weight
Death-Coded Outcome Share
Newfoundland death-coded reports 7.2%
Cross-breed median
7.2% of 1,261 newfoundland reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 49.0 kg (108.0 lbs)
Top Reported Reactions
Vomiting 216
Diarrhoea 118
Lack of efficacy - NOS 84
Lack of efficacy (endoparasite) - hookworm 81
Lethargy (see also Central nervous system depression in 'Neurological') 80
Emesis 68
Anorexia 62
Death by euthanasia 53
INEFFECTIVE, HEARTWORM LARVAE 50
Digestive tract disorder NOS 45
Other abnormal test result NOS 40
Lack of efficacy (endoparasite) - heartworm 39
Not eating 38
Panting 37
Death 34
Most Referenced Drugs
Ivermectin + Pyrantel As Pamoate Salt 176
Milbemycin Oxime + Spinosad 157
Afoxolaner 107
Pyrantel Pamoate;Sarolaner 97
Carprofen 85
Milbemycin Oxime + Praziquantel 81
Oclacitinib Maleate 75
Bedinvetmab 72
Fluralaner Chew Tablets 65
Spinosad 49
Moxidectin 48
Fluralaner 13.64% 12-Week Chew 41
Selamectin 34
Grapiprant 34
Gabapentin 34
Outcome Breakdown
Outcome Unknown
356 (30.5%)
Ongoing
350 (29.9%)
Recovered/Normal
333 (28.5%)
Died
47 (4.0%)
Euthanized
45 (3.8%)
Recovered with Sequela
38 (3.3%)
Gender Distribution
Male 656 (52.0%)
Female 576 (45.7%)
Unknown 20 (1.6%)
Mixed 9 (0.7%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 43 | |
| 2011 | 73 | |
| 2012 | 72 | |
| 2013 | 50 | |
| 2014 | 93 | |
| 2015 | 83 | |
| 2016 | 109 | |
| 2017 | 104 | |
| 2018 | 79 | |
| 2019 | 72 | |
| 2020 | 80 | |
| 2021 | 65 | |
| 2022 | 74 | |
| 2023 | 88 | |
| 2024 | 124 | |
| 2025 | 52 | |
Newfoundland Pet Health Insights
Newfoundland accounts for 1,261 FDA adverse event reports, ranking #96 by volume among dog breeds, with 91 reports (7.2%) coded as a death outcome. Mean age at report: 4.8 years, average weight 49.0 kg (108.0 lbs).
Top reported signs: Vomiting (216), Diarrhoea (118), Lack of efficacy - NOS (84). Most-referenced drug: Ivermectin + Pyrantel As Pamoate Salt (176 reports), followed by Milbemycin Oxime + Spinosad (157) and Afoxolaner (107).
Outcome coding on 1,169 status-recorded reports is dominated by Outcome Unknown (30.5%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Shar Pei
1,258 reports · 7.6% death rate
Saint Bernard Dog
1,253 reports · 7.8% death rate
Shepherd Dog (unspecified)
1,271 reports · 3.2% death rate
Spaniel - Cocker English
1,243 reports · 2.5% death rate
Ridgeback - Rhodesian
1,291 reports · 5.2% death rate
Coonhound (unspecified)
1,210 reports · 3.0% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Newfoundland? ▼
There are 1,261 adverse event reports involving Newfoundland in the FDA database, with 91 reports involving death (7.2% death rate). Newfoundland ranks #96 by report volume.
What are the most common adverse reactions reported for Newfoundland? ▼
The most commonly reported adverse reactions for Newfoundland are Vomiting (216 reports), Diarrhoea (118 reports), Lack of efficacy - NOS (84 reports), Lack of efficacy (endoparasite) - hookworm (81 reports), Lethargy (see also Central nervous system depression in 'Neurological') (80 reports).
What drugs are most frequently associated with Newfoundland adverse events? ▼
The drugs most frequently referenced in Newfoundland adverse event reports are Ivermectin + Pyrantel As Pamoate Salt (176 reports), Milbemycin Oxime + Spinosad (157 reports), Afoxolaner (107 reports), Pyrantel Pamoate;Sarolaner (97 reports), Carprofen (85 reports).
What is the average age of Newfoundland in adverse event reports? ▼
The average age of Newfoundland at the time of adverse event reports is 4.8 years, with an average weight of 49.0 kg (108.0 lbs).
Does a high number of adverse event reports mean Newfoundland is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Newfoundland safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.