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2026 FDA CVM data 2,607 reports on file official source

Terrier - Bull - Staffordshire — FDA Adverse Event Profile

Adverse-event records and label data for Terrier - Bull - Staffordshire (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 296 222 148 74 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Terrier - Bull - Staffordshire drawn from FDA CVM filings.

Terrier - Bull - Staffordshire (Dog) has 2,607 FDA adverse event reports on record, with 116 deaths reported (440.0% death rate) — ranking #68 by report volume. The most frequently reported reaction is Vomiting (510 cases). The top associated drug is Moxidectin. Average age at report: 5.0 years.

Total Reports

2,607

FDA CVM filings

Deaths Reported

116

of 2,607 reports

Death Rate

440.0%

death-coded share

Avg Age at Report

5.0 yr

26.7 kg avg weight

Death-Coded Outcome Share

Terrier - Bull - Staffordshire death-coded reports 100.0%
Database median

440.0% of 2,607 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 26.7 kg (58.9 lbs)

Top Reported Reactions

Vomiting 510
Lethargy (see also Central nervous system depression in 'Neurological') 248
Lack of efficacy (endoparasite) - heartworm 207
Diarrhoea 192
Emesis 170
Lack of efficacy - NOS 154
Hives (see also 'Skin') 138
Lack of efficacy (endoparasite) - hookworm 128
INEFFECTIVE, HEARTWORM LARVAE 98
Facial swelling (see also 'Skin') 97
Seizure NOS 96
Anorexia 87
Lack of efficacy (ectoparasite) - flea 76
Death by euthanasia 68
Lethargy (see also Central nervous system depression in Neurological) 66

Most Referenced Drugs

Moxidectin 322
Milbemycin Oxime + Spinosad 310
Ivermectin + Pyrantel As Pamoate Salt 274
Pyrantel Pamoate;Sarolaner 240
Oclacitinib Maleate 181
Bedinvetmab 140
Afoxolaner 127
Carprofen 86
Fluralaner Chew Tablets 85
Sarolaner 84
Spinosad 81
Melarsomine Dihydrochloride 53
Anti-Il31 Mab Mcs Lot #1283563 53
Gabapentin 53
Fluralaner 13.64% 12-Week Chew 53

Outcome Breakdown

Ongoing
851 (33.4%)
Recovered/Normal
756 (29.7%)
Outcome Unknown
734 (28.8%)
Recovered with Sequela
91 (3.6%)
Euthanized
70 (2.7%)
Died
46 (1.8%)

Gender Distribution

Female 1,375 (52.7%)
Male 1,192 (45.7%)
Unknown 37 (1.4%)
Mixed 3 (0.1%)

Reports by Year

Year Reports Trend
2010 25
2011 52
2012 94
2013 133
2014 152
2015 194
2016 196
2017 211
2018 155
2019 189
2020 160
2021 223
2022 185
2023 178
2024 296
2025 164
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Terrier - Bull - Staffordshire sits in the registered size-class taxonomy. Average reported weight: 26.7 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Terrier - Bull - Staffordshire Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Terrier - Bull - Staffordshire accounts for 2,607 submitted reports and currently ranks #68 by report volume within the dog population. Of those reports, 116 involved a death outcome — a 440.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 5.0 years, with an average recorded body weight of 26.7 kg (58.9 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Terrier - Bull - Staffordshire are Vomiting (510 reports), Lethargy (see also Central nervous system depression in 'Neurological') (248 reports), Lack of efficacy (endoparasite) - heartworm (207 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Moxidectin appears in 322 reports and is the single most-referenced drug, followed by Milbemycin Oxime + Spinosad (310) and Ivermectin + Pyrantel As Pamoate Salt (274). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 2,548 reports with a recorded status is dominated by Ongoing (33.4% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Terrier - Bull - Staffordshire Adverse Event Data

Terrier - Bull - Staffordshire has a moderate volume of adverse event reports (2,607). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 440.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Moxidectin, appearing in 322 reports. This may indicate widespread use of the medication rather than a specific safety concern for Terrier - Bull - Staffordshire.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Terrier - Bull - Staffordshire?
There are 2,607 adverse event reports involving Terrier - Bull - Staffordshire in the FDA database, with 116 reports involving death (440.0% death rate). Terrier - Bull - Staffordshire ranks #68 by report volume.
What are the most common adverse reactions reported for Terrier - Bull - Staffordshire?
The most commonly reported adverse reactions for Terrier - Bull - Staffordshire are Vomiting (510 reports), Lethargy (see also Central nervous system depression in 'Neurological') (248 reports), Lack of efficacy (endoparasite) - heartworm (207 reports), Diarrhoea (192 reports), Emesis (170 reports).
What drugs are most frequently associated with Terrier - Bull - Staffordshire adverse events?
The drugs most frequently referenced in Terrier - Bull - Staffordshire adverse event reports are Moxidectin (322 reports), Milbemycin Oxime + Spinosad (310 reports), Ivermectin + Pyrantel As Pamoate Salt (274 reports), Pyrantel Pamoate;Sarolaner (240 reports), Oclacitinib Maleate (181 reports).
What is the average age of Terrier - Bull - Staffordshire in adverse event reports?
The average age of Terrier - Bull - Staffordshire at the time of adverse event reports is 5.0 years, with an average weight of 26.7 kg (58.9 lbs).
Does a high number of adverse event reports mean Terrier - Bull - Staffordshire is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Bull - Staffordshire safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Terrier - Bull - Staffordshire ranks #68 by total report volume. Death rate (440.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial