Total Reports
2,607
FDA CVM filings
Dog /
FDA CVM · 2025 release 2,607 reports on file
Terrier - Bull - Staffordshire - FDA Adverse Event Profile
Adverse-event records for Terrier - Bull - Staffordshire (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Terrier - Bull - Staffordshire is #68 by FDA report volume; 4.4% of its 2,607 reports (116) were death-coded.
- #68
- most-reported dog breed
- 4.4%
- death-coded report share
- 510
- Vomiting - top reaction
- 5.0 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
116
of 2,607 reports
Death Rate
4.4%
death-coded share
Avg Age at Report
5.0 yr
26.7 kg avg weight
Death-Coded Outcome Share
Terrier - Bull - Staffordshire death-coded reports 4.4%
Cross-breed median
4.4% of 2,607 terrier - bull - staffordshire reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 26.7 kg (58.9 lbs)
Top Reported Reactions
Vomiting 510
Lethargy (see also Central nervous system depression in 'Neurological') 248
Lack of efficacy (endoparasite) - heartworm 207
Diarrhoea 192
Emesis 170
Lack of efficacy - NOS 154
Hives (see also 'Skin') 138
Lack of efficacy (endoparasite) - hookworm 128
INEFFECTIVE, HEARTWORM LARVAE 98
Facial swelling (see also 'Skin') 97
Seizure NOS 96
Anorexia 87
Lack of efficacy (ectoparasite) - flea 76
Death by euthanasia 68
Lethargy (see also Central nervous system depression in Neurological) 66
Most Referenced Drugs
Moxidectin 322
Milbemycin Oxime + Spinosad 310
Ivermectin + Pyrantel As Pamoate Salt 274
Pyrantel Pamoate;Sarolaner 240
Oclacitinib Maleate 181
Bedinvetmab 140
Afoxolaner 127
Carprofen 86
Fluralaner Chew Tablets 85
Sarolaner 84
Spinosad 81
Melarsomine Dihydrochloride 53
Anti-Il31 Mab Mcs Lot #1283563 53
Gabapentin 53
Fluralaner 13.64% 12-Week Chew 53
Outcome Breakdown
Ongoing
851 (33.4%)
Recovered/Normal
756 (29.7%)
Outcome Unknown
734 (28.8%)
Recovered with Sequela
91 (3.6%)
Euthanized
70 (2.7%)
Died
46 (1.8%)
Gender Distribution
Female 1,375 (52.7%)
Male 1,192 (45.7%)
Unknown 37 (1.4%)
Mixed 3 (0.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 25 | |
| 2011 | 52 | |
| 2012 | 94 | |
| 2013 | 133 | |
| 2014 | 152 | |
| 2015 | 194 | |
| 2016 | 196 | |
| 2017 | 211 | |
| 2018 | 155 | |
| 2019 | 189 | |
| 2020 | 160 | |
| 2021 | 223 | |
| 2022 | 185 | |
| 2023 | 178 | |
| 2024 | 296 | |
| 2025 | 164 | |
Terrier - Bull - Staffordshire Pet Health Insights
Terrier - Bull - Staffordshire accounts for 2,607 FDA adverse event reports, ranking #68 by volume among dog breeds, with 116 reports (4.4%) coded as a death outcome. Mean age at report: 5.0 years, average weight 26.7 kg (58.9 lbs).
Top reported signs: Vomiting (510), Lethargy (see also Central nervous system depression in 'Neurological') (248), Lack of efficacy (endoparasite) - heartworm (207). Most-referenced drug: Moxidectin (322 reports), followed by Milbemycin Oxime + Spinosad (310) and Ivermectin + Pyrantel As Pamoate Salt (274).
Outcome coding on 2,548 status-recorded reports is dominated by Ongoing (33.4%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Terrier - Bull - Staffordshire? ▼
There are 2,607 adverse event reports involving Terrier - Bull - Staffordshire in the FDA database, with 116 reports involving death (4.4% death rate). Terrier - Bull - Staffordshire ranks #68 by report volume.
What are the most common adverse reactions reported for Terrier - Bull - Staffordshire? ▼
The most commonly reported adverse reactions for Terrier - Bull - Staffordshire are Vomiting (510 reports), Lethargy (see also Central nervous system depression in 'Neurological') (248 reports), Lack of efficacy (endoparasite) - heartworm (207 reports), Diarrhoea (192 reports), Emesis (170 reports).
What drugs are most frequently associated with Terrier - Bull - Staffordshire adverse events? ▼
The drugs most frequently referenced in Terrier - Bull - Staffordshire adverse event reports are Moxidectin (322 reports), Milbemycin Oxime + Spinosad (310 reports), Ivermectin + Pyrantel As Pamoate Salt (274 reports), Pyrantel Pamoate;Sarolaner (240 reports), Oclacitinib Maleate (181 reports).
What is the average age of Terrier - Bull - Staffordshire in adverse event reports? ▼
The average age of Terrier - Bull - Staffordshire at the time of adverse event reports is 5.0 years, with an average weight of 26.7 kg (58.9 lbs).
Does a high number of adverse event reports mean Terrier - Bull - Staffordshire is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Bull - Staffordshire safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.