Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
9,078
Total Reports
630
Deaths Reported
690.0%
Death Rate
7.5 yr
Avg Age at Report
Average weight at time of report: 4.9 kg (10.8 lbs)
Top Reported Reactions
Vomiting 1,102
Lethargy (see also Central nervous system depression in 'Neurological') 963
Lack of efficacy (ectoparasite) - flea 941
Emesis 569
Behavioural disorder NOS 542
Lack of efficacy - NOS 523
Anorexia 510
Application site hair loss 503
Panting 489
Weight loss 488
Diarrhoea 456
Vocalisation 405
Hyperactivity 401
Not eating 377
Application site alopecia 349
Most Referenced Drugs
Spinosad 1,226
Nitenpyram 1,020
Fluralaner Spot-On Solution 911
Selamectin 846
Frunevetmab 617
Imidacloprid + Moxidectin 596
Cefovecin 464
Selamectin;Sarolaner 454
Buprenorphine 377
Emodepside + Praziquantel 322
Velagliflozin Proline Monohydrate 275
Bexagliflozin 258
Fluralaner/Moxidectin Spot-On 230
Maropitant Citrate 220
Robenacoxib 203
Outcome Breakdown
Outcome Unknown
2,888 (31.8%)
Ongoing
2,874 (31.6%)
Recovered/Normal
2,648 (29.1%)
Died
361 (4.0%)
Euthanized
269 (3.0%)
Recovered with Sequela
46 (0.5%)
Gender Distribution
Male 4,643 (51.1%)
Female 4,289 (47.2%)
Unknown 94 (1.0%)
Mixed 52 (0.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 19 | |
| 2011 | 105 | |
| 2012 | 368 | |
| 2013 | 627 | |
| 2014 | 592 | |
| 2015 | 600 | |
| 2016 | 622 | |
| 2017 | 747 | |
| 2018 | 664 | |
| 2019 | 608 | |
| 2020 | 559 | |
| 2021 | 443 | |
| 2022 | 506 | |
| 2023 | 938 | |
| 2024 | 1,118 | |
| 2025 | 562 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #21 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.