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Breed profile · FDA CVM July 2026 extract

Domestic Longhair adverse-event record

Adverse-event filings for Domestic Longhair (Cat) in the FDA Center for Veterinary Medicine openFDA extract. Browse cat breeds, reactions, and outcomes below.

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#21 of 510
by report volume (all breeds)
9,615
FDA CVM reports on file
7.0%
death-coded share of reports
#88 of 275
by death-coded share (≥50 reports)

How the 9,615 reports break down

By recorded gender -- every report on file for Domestic Longhair, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 1,128 846 564 282 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Domestic Longhair drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Domestic Longhair ranks #21 of 510 by total reports (9,615) and #88 of 275 by death-coded share (7.0%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#21
This breed, reports of 510
#88
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Domestic Longhair has 9,615 reports now versus 9,400 in that prior snapshot: 215 more (2.3%).

Report change
+215
Death-coded reports
+16
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Domestic Longhair changes

Total Reports

9,615

Highest-reported breed

Deaths Reported

670

of 9,615 reports

Death-coded share of reports

7.0%

Above-median death-coded share

Avg Age at Report

7.6 yr

4.9 kg avg weight

Breed Safety Scorecard

F (27/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate F
7.0%

Share of reports coded as a fatality

Euthanasia rate F
3.1%

Share of reports resulting in euthanasia

Full recovery rate D
28.6%

Share of reports coded "Recovered/Normal"

5-year trend F
+109%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Domestic Longhair death-coded reports 7.0%
Cross-breed median

7.0% of 9,615 domestic longhair reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Domestic Longhair's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

7% 68th percentile Higher share than 68% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Domestic Longhair 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Domestic Longhair among report-volume vs. death-rate peers

Every breed shown has at least 50 filed reports. Volume reflects how often a breed is reported, not how common it is; death rate is the share of a breed's own reports coded as a death outcome.

Source: FDA openFDA Animal & Veterinary Adverse Events database 2×2 strategic matrix plotting 30 entities by Total Reports (X) and Death Rate (%) (Y), with a crosshair dividing the plot into four quadrants. High volume, high death rateLow volume, high death rateHigh volume, low death rateLow volume, low death rate 020,00040,00060,00080,000100,000 0%5%10%15% Total Reports Death Rate (%) Domestic Longhair vs. all breeds, report volume and death-coded share Retriever - Labrador-93675, 3.7%Crossbred Canine/dog-70591, 3.2%Domestic Shorthair-65226, 7.2%Dog (unknown)-48820, 8.8%Retriever - Golden-35980, 3.7%Shepherd Dog - German-32220, 4.4%Chihuahua-31521, 4.2%Terrier - Yorkshire-24924, 3.7%Shih Tzu-24405, 3.6%Boxer (German Boxer)-19405, 4.4%Beagle-17970, 3.6%Pit Bull-17865, 3.1%Shepherd Dog - Australian-16274, 3.7%Terrier (unspecified)-14058, 3.1%Maltese-13940, 3.2%Dachshund (unspecified)-13512, 4.6%Cat (unknown)-13248, 9.3%Terrier - Jack Russell-10423, 3.7%Collie - Border-10130, 4.3%Siberian Husky-9811, 4.5%Domestic Longhair-9615, 7%Pug-9224, 5.2%Spitz - German Pomeranian-9086, 4.9%Terrier - Bull - American Pit-8769, 4.7%Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)-7871, 3.6%Terrier - Boston-7737, 4.5%Spaniel - Cocker American-7640, 4%Domestic (unspecified)-7576, 13.4%Poodle (unspecified)-7534, 3.4%Schnauzer - Miniature-7513, 4.4%
Source: FDA openFDA Animal & Veterinary Adverse Events database
Average weight at time of report: 4.9 kg (10.8 lbs)

Top Reported Reactions

Vomiting 1,167
Lack of efficacy (ectoparasite) - flea 1,013
Lethargy (see also Central nervous system depression in 'Neurological') 963
Lack of efficacy - NOS 580
Emesis 570
Behavioural disorder NOS 566
Weight loss 539
Anorexia 538
Application site hair loss 522
Panting 499
Diarrhoea 498
Hyperactivity 420
Vocalisation 415
Not eating 404
Lethargy (see also Central nervous system depression in Neurological) 362

Most Referenced Drugs

Spinosad 1,226
Nitenpyram 1,041
Fluralaner Spot-On Solution 968
Selamectin 862
Frunevetmab 692
Imidacloprid + Moxidectin 597
Selamectin;Sarolaner 489
Cefovecin 485
Buprenorphine 403
Velagliflozin Proline Monohydrate 364
Emodepside + Praziquantel 328
Bexagliflozin 307
Fluralaner/Moxidectin Spot-On 254
Maropitant Citrate 250
Robenacoxib 226

Outcome Breakdown

Ongoing
3,098 (32.2%)
Outcome Unknown
3,060 (31.8%)
Recovered/Normal
2,746 (28.5%)
Died
375 (3.9%)
Euthanized
295 (3.1%)
Recovered with Sequela
49 (0.5%)

Gender Distribution

Male 4,898 (50.9%)
Female 4,560 (47.4%)
Unknown 104 (1.1%)
Mixed 53 (0.6%)

Reports by Year

Year Reports Trend
2010 19
2011 105
2012 368
2013 627
2014 592
2015 600
2016 622
2017 747
2018 664
2019 608
2020 559
2021 443
2022 508
2023 938
2024 1,128
2025 924
2026 163

Domestic Longhair: high death-coded share in the FDA CVM extract

Signature read: 9,615 reports place Domestic Longhair in the upper third of breed filing volume (#21 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Domestic Longhair sits at #21 of 510 by report volume among all breeds and #3 of 55 among cat breeds, with 9,615 reports and 670 (7.0%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #88 of 275. Mean age at report: 7.6 years, average weight 4.9 kg (10.8 lbs).

Top reported signs: Vomiting (1,167), Lack of efficacy (ectoparasite) - flea (1,013), Lethargy (see also Central nervous system depression in 'Neurological') (963). Most-referenced drug: Spinosad (1,226 reports), followed by Nitenpyram (1,041) and Fluralaner Spot-On Solution (968).

Outcome coding on 9,623 status-recorded reports is dominated by Ongoing (32.2%). Annual submissions ranged 19-2,026 across 17 years on file.

Cat Breeds With a Similar Report Volume

Showing 6 of 54 cat breeds in our dataset, ranked by closest report volume.

Domestic (unspecified)
7,576 reports · 13.4% death-coded
Domestic Mediumhair
6,441 reports · 7.7% death-coded
Cat (unknown)
13,248 reports · 9.3% death-coded
Cat (other)
4,798 reports · 9.7% death-coded
Siamese
3,073 reports · 8.1% death-coded
Maine Coon
2,383 reports · 7.6% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Domestic Longhair drawn from openFDA outside the Cat family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (7.0% death-coded here).

American Pit Bull Terrier 7.0% · Dog Terrier - Kerry Blue 6.9% · Dog Newfoundland 7.0% · Dog Spaniel - American Water 7.0% · Dog

What to do with this cat

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Domestic Longhair? ▼
There are 9,615 adverse event reports involving Domestic Longhair in the FDA database, of which 670 were death-coded (7.0% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Domestic Longhair ranks #21 of 510 by report volume among all breeds PlainBreed indexes (#3 of 55 among cat breeds).
Where does Domestic Longhair sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Domestic Longhair is #21 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Cat, it is #3 of 55. Among breeds with at least 50 reports, its death-coded share ranks #88 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Domestic Longhair? ▼
The most commonly reported adverse reactions for Domestic Longhair are Vomiting (1,167 reports), Lack of efficacy (ectoparasite) - flea (1,013 reports), Lethargy (see also Central nervous system depression in 'Neurological') (963 reports), Lack of efficacy - NOS (580 reports), Emesis (570 reports).
What drugs are most frequently associated with Domestic Longhair adverse events? ▼
The drugs most frequently referenced in Domestic Longhair adverse event reports are Spinosad (1,226 reports), Nitenpyram (1,041 reports), Fluralaner Spot-On Solution (968 reports), Selamectin (862 reports), Frunevetmab (692 reports).
What is the average age of Domestic Longhair in adverse event reports? ▼
The average age of Domestic Longhair at the time of adverse event reports is 7.6 years, with an average weight of 4.9 kg (10.8 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Domestic Longhair (Cat), extract as of July 2026 extract. 9,615 reports · 670 death-coded (7.0% of reports, not a mortality rate) · #21 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →