Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
6,057
Total Reports
460
Deaths Reported
760.0%
Death Rate
6.7 yr
Avg Age at Report
Average weight at time of report: 4.8 kg (10.6 lbs)
Top Reported Reactions
Vomiting 757
Lethargy (see also Central nervous system depression in 'Neurological') 656
Lack of efficacy (ectoparasite) - flea 560
Application site hair loss 451
Emesis 378
Behavioural disorder NOS 350
Application site alopecia 327
Weight loss 316
Anorexia 301
Diarrhoea 290
Ataxia 263
Lack of efficacy - NOS 261
Lethargy (see also Central nervous system depression in Neurological) 259
Not eating 255
Hyperactivity 222
Most Referenced Drugs
Spinosad 786
Fluralaner Spot-On Solution 663
Selamectin 635
Nitenpyram 470
Selamectin;Sarolaner 402
Imidacloprid + Moxidectin 385
Frunevetmab 354
Emodepside + Praziquantel 301
Cefovecin 285
Buprenorphine 276
Maropitant Citrate 205
Fluralaner/Moxidectin Spot-On 194
Velagliflozin Proline Monohydrate 194
Bexagliflozin 166
Robenacoxib 165
Outcome Breakdown
Ongoing
1,965 (32.4%)
Recovered/Normal
1,808 (29.8%)
Outcome Unknown
1,792 (29.5%)
Died
250 (4.1%)
Euthanized
210 (3.5%)
Recovered with Sequela
40 (0.7%)
Gender Distribution
Male 3,065 (50.6%)
Female 2,895 (47.8%)
Unknown 65 (1.1%)
Mixed 32 (0.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 8 | |
| 2011 | 52 | |
| 2012 | 228 | |
| 2013 | 373 | |
| 2014 | 341 | |
| 2015 | 351 | |
| 2016 | 374 | |
| 2017 | 437 | |
| 2018 | 472 | |
| 2019 | 449 | |
| 2020 | 403 | |
| 2021 | 360 | |
| 2022 | 378 | |
| 2023 | 589 | |
| 2024 | 809 | |
| 2025 | 433 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #35 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.