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2026 FDA CVM data 13,509 reports on file official source

Terrier (unspecified) — FDA Adverse Event Profile

Adverse-event records and label data for Terrier (unspecified) (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 1,210 907.5 605 302.5 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Terrier (unspecified) drawn from FDA CVM filings.

Terrier (unspecified) (Dog) has 13,509 FDA adverse event reports on record, with 411 deaths reported (300.0% death rate) — ranking #15 by report volume. The most frequently reported reaction is Vomiting (2,628 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 5.8 years.

Total Reports

13,509

FDA CVM filings

Deaths Reported

411

of 13,509 reports

Death Rate

300.0%

death-coded share

Avg Age at Report

5.8 yr

11.6 kg avg weight

Death-Coded Outcome Share

Terrier (unspecified) death-coded reports 100.0%
Database median

300.0% of 13,509 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 11.6 kg (25.6 lbs)

Top Reported Reactions

Vomiting 2,628
Emesis 1,484
Lethargy (see also Central nervous system depression in 'Neurological') 1,172
Lack of efficacy (endoparasite) - heartworm 1,120
Lack of efficacy (ectoparasite) - flea 886
Diarrhoea 838
Lack of efficacy - NOS 715
Lack of efficacy (endoparasite) - hookworm 641
Seizure NOS 570
INEFFECTIVE, HEARTWORM LARVAE 564
Not eating 339
Anorexia 336
Behavioural disorder NOS 325
Digestive tract disorder NOS 311
Emesis (multiple) 304

Most Referenced Drugs

Milbemycin Oxime + Spinosad 2,881
Ivermectin + Pyrantel As Pamoate Salt 1,429
Pyrantel Pamoate;Sarolaner 1,048
Spinosad 998
Moxidectin 885
Fluralaner Chew Tablets 711
Afoxolaner 704
Milbemycin Oxime + Praziquantel 532
Fluralaner 13.64% 12-Week Chew 516
Oclacitinib Maleate 500
Trilostane 404
Sarolaner 366
Bedinvetmab 333
Ivermectin 234
Carprofen 232

Outcome Breakdown

Recovered/Normal
4,716 (34.9%)
Outcome Unknown
3,943 (29.2%)
Ongoing
3,865 (28.6%)
Recovered with Sequela
574 (4.2%)
Euthanized
215 (1.6%)
Died
196 (1.5%)

Gender Distribution

Female 6,737 (49.9%)
Male 6,586 (48.8%)
Unknown 173 (1.3%)
Mixed 13 (0.1%)

Reports by Year

Year Reports Trend
2010 20
2011 348
2012 997
2013 802
2014 831
2015 954
2016 964
2017 1,069
2018 1,010
2019 1,011
2020 948
2021 888
2022 774
2023 937
2024 1,210
2025 746
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Terrier (unspecified) sits in the registered size-class taxonomy. Average reported weight: 11.6 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Terrier (unspecified) Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Terrier (unspecified) accounts for 13,509 submitted reports and currently ranks #15 by report volume within the dog population. Of those reports, 411 involved a death outcome — a 300.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 5.8 years, with an average recorded body weight of 11.6 kg (25.6 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Terrier (unspecified) are Vomiting (2,628 reports), Emesis (1,484 reports), Lethargy (see also Central nervous system depression in 'Neurological') (1,172 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 2,881 reports and is the single most-referenced drug, followed by Ivermectin + Pyrantel As Pamoate Salt (1,429) and Pyrantel Pamoate;Sarolaner (1,048). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 13,509 reports with a recorded status is dominated by Recovered/Normal (34.9% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Terrier (unspecified) Adverse Event Data

With 13,509 adverse event reports, Terrier (unspecified) has one of the larger report volumes in the FDA database. This typically reflects breed popularity rather than inherent health risk — more pets of a breed means more veterinary encounters and more opportunity for adverse event reporting.

The 300.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 2,881 reports. This may indicate widespread use of the medication rather than a specific safety concern for Terrier (unspecified).

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Terrier (unspecified)?
There are 13,509 adverse event reports involving Terrier (unspecified) in the FDA database, with 411 reports involving death (300.0% death rate). Terrier (unspecified) ranks #15 by report volume.
What are the most common adverse reactions reported for Terrier (unspecified)?
The most commonly reported adverse reactions for Terrier (unspecified) are Vomiting (2,628 reports), Emesis (1,484 reports), Lethargy (see also Central nervous system depression in 'Neurological') (1,172 reports), Lack of efficacy (endoparasite) - heartworm (1,120 reports), Lack of efficacy (ectoparasite) - flea (886 reports).
What drugs are most frequently associated with Terrier (unspecified) adverse events?
The drugs most frequently referenced in Terrier (unspecified) adverse event reports are Milbemycin Oxime + Spinosad (2,881 reports), Ivermectin + Pyrantel As Pamoate Salt (1,429 reports), Pyrantel Pamoate;Sarolaner (1,048 reports), Spinosad (998 reports), Moxidectin (885 reports).
What is the average age of Terrier (unspecified) in adverse event reports?
The average age of Terrier (unspecified) at the time of adverse event reports is 5.8 years, with an average weight of 11.6 kg (25.6 lbs).
Does a high number of adverse event reports mean Terrier (unspecified) is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier (unspecified) safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Terrier (unspecified) ranks #15 by total report volume. Death rate (300.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial