Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
61,410
Total Reports
4,445
Deaths Reported
720.0%
Death Rate
7.0 yr
Avg Age at Report
Average weight at time of report: 4.9 kg (10.8 lbs)
Top Reported Reactions
Vomiting 7,669
Lethargy (see also Central nervous system depression in 'Neurological') 5,954
Application site hair loss 5,129
Lack of efficacy (ectoparasite) - flea 4,360
Application site alopecia 3,571
Emesis 3,444
Anorexia 3,356
Lack of efficacy - NOS 3,298
Behavioural disorder NOS 3,243
Weight loss 3,070
Diarrhoea 2,876
Hypersalivation 2,587
Ataxia 2,457
Not eating 2,420
Lethargy (see also Central nervous system depression in Neurological) 2,294
Most Referenced Drugs
Selamectin 6,642
Spinosad 6,477
Fluralaner Spot-On Solution 5,905
Selamectin;Sarolaner 4,234
Frunevetmab 4,102
Imidacloprid + Moxidectin 3,794
Nitenpyram 3,383
Cefovecin 3,307
Emodepside + Praziquantel 3,145
Buprenorphine 2,770
Velagliflozin Proline Monohydrate 2,165
Bexagliflozin 2,017
Fluralaner/Moxidectin Spot-On 1,812
Maropitant Citrate 1,788
Robenacoxib 1,691
Outcome Breakdown
Ongoing
20,573 (33.5%)
Outcome Unknown
18,504 (30.1%)
Recovered/Normal
17,552 (28.6%)
Died
2,314 (3.8%)
Euthanized
2,133 (3.5%)
Recovered with Sequela
399 (0.6%)
Gender Distribution
Male 32,361 (52.7%)
Female 27,822 (45.3%)
Unknown 831 (1.4%)
Mixed 396 (0.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 134 | |
| 2011 | 828 | |
| 2012 | 2,573 | |
| 2013 | 3,930 | |
| 2014 | 3,457 | |
| 2015 | 3,519 | |
| 2016 | 3,740 | |
| 2017 | 4,465 | |
| 2018 | 4,195 | |
| 2019 | 4,256 | |
| 2020 | 3,742 | |
| 2021 | 3,405 | |
| 2022 | 3,698 | |
| 2023 | 6,440 | |
| 2024 | 8,383 | |
| 2025 | 4,645 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #3 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.