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2026 FDA CVM data 7,526 reports on file official source

Terrier - Boston — FDA Adverse Event Profile

Adverse-event records and label data for Terrier - Boston (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 560 420 280 140 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Terrier - Boston drawn from FDA CVM filings.

Terrier - Boston (Dog) has 7,526 FDA adverse event reports on record, with 345 deaths reported (460.0% death rate) — ranking #28 by report volume. The most frequently reported reaction is Vomiting (1,594 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 5.7 years.

Total Reports

7,526

FDA CVM filings

Deaths Reported

345

of 7,526 reports

Death Rate

460.0%

death-coded share

Avg Age at Report

5.7 yr

10.2 kg avg weight

Death-Coded Outcome Share

Terrier - Boston death-coded reports 100.0%
Database median

460.0% of 7,526 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 10.2 kg (22.5 lbs)

Top Reported Reactions

Vomiting 1,594
Emesis 831
Lethargy (see also Central nervous system depression in 'Neurological') 674
Diarrhoea 550
Lack of efficacy (endoparasite) - hookworm 435
Lack of efficacy - NOS 403
Seizure NOS 370
Lack of efficacy (ectoparasite) - flea 316
INEFFECTIVE, HEARTWORM LARVAE 265
Anorexia 238
Digestive tract disorder NOS 237
Lack of efficacy (endoparasite) - heartworm 236
Other abnormal test result NOS 220
Elevated alanine aminotransferase (ALT) 213
Behavioural disorder NOS 184

Most Referenced Drugs

Milbemycin Oxime + Spinosad 1,571
Trilostane 646
Ivermectin + Pyrantel As Pamoate Salt 639
Spinosad 555
Moxidectin 431
Afoxolaner 371
Oclacitinib Maleate 365
Pyrantel Pamoate;Sarolaner 322
Fluralaner Chew Tablets 298
Milbemycin Oxime + Praziquantel 224
Fluralaner 13.64% 12-Week Chew 149
Carprofen 139
Sarolaner 131
Selamectin 119
Maropitant Citrate 117

Outcome Breakdown

Recovered/Normal
2,580 (37.2%)
Outcome Unknown
2,152 (31.0%)
Ongoing
1,608 (23.2%)
Recovered with Sequela
257 (3.7%)
Died
187 (2.7%)
Euthanized
158 (2.3%)

Gender Distribution

Female 3,694 (49.1%)
Male 3,669 (48.8%)
Unknown 145 (1.9%)
Mixed 18 (0.2%)

Reports by Year

Year Reports Trend
2010 298
2011 433
2012 618
2013 629
2014 594
2015 562
2016 517
2017 580
2018 479
2019 560
2020 451
2021 406
2022 370
2023 398
2024 379
2025 252
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Terrier - Boston sits in the registered size-class taxonomy. Average reported weight: 10.2 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Terrier - Boston Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Terrier - Boston accounts for 7,526 submitted reports and currently ranks #28 by report volume within the dog population. Of those reports, 345 involved a death outcome — a 460.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 5.7 years, with an average recorded body weight of 10.2 kg (22.5 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Terrier - Boston are Vomiting (1,594 reports), Emesis (831 reports), Lethargy (see also Central nervous system depression in 'Neurological') (674 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 1,571 reports and is the single most-referenced drug, followed by Trilostane (646) and Ivermectin + Pyrantel As Pamoate Salt (639). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 6,942 reports with a recorded status is dominated by Recovered/Normal (37.2% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Terrier - Boston Adverse Event Data

With 7,526 adverse event reports, Terrier - Boston has one of the larger report volumes in the FDA database. This typically reflects breed popularity rather than inherent health risk — more pets of a breed means more veterinary encounters and more opportunity for adverse event reporting.

The 460.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 1,571 reports. This may indicate widespread use of the medication rather than a specific safety concern for Terrier - Boston.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Terrier - Boston?
There are 7,526 adverse event reports involving Terrier - Boston in the FDA database, with 345 reports involving death (460.0% death rate). Terrier - Boston ranks #28 by report volume.
What are the most common adverse reactions reported for Terrier - Boston?
The most commonly reported adverse reactions for Terrier - Boston are Vomiting (1,594 reports), Emesis (831 reports), Lethargy (see also Central nervous system depression in 'Neurological') (674 reports), Diarrhoea (550 reports), Lack of efficacy (endoparasite) - hookworm (435 reports).
What drugs are most frequently associated with Terrier - Boston adverse events?
The drugs most frequently referenced in Terrier - Boston adverse event reports are Milbemycin Oxime + Spinosad (1,571 reports), Trilostane (646 reports), Ivermectin + Pyrantel As Pamoate Salt (639 reports), Spinosad (555 reports), Moxidectin (431 reports).
What is the average age of Terrier - Boston in adverse event reports?
The average age of Terrier - Boston at the time of adverse event reports is 5.7 years, with an average weight of 10.2 kg (22.5 lbs).
Does a high number of adverse event reports mean Terrier - Boston is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Boston safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Terrier - Boston ranks #28 by total report volume. Death rate (460.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial