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Breed profile · FDA CVM July 2026 extract

Spaniel (unspecified) adverse-event record

Adverse-event filings for Spaniel (unspecified) (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#57 of 510
by report volume (all breeds)
3,209
FDA CVM reports on file
4.8%
death-coded share of reports
#138 of 275
by death-coded share (≥50 reports)

How the 3,209 reports break down

By recorded gender -- every report on file for Spaniel (unspecified), no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 324 243 162 81 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Spaniel (unspecified) drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Spaniel (unspecified) ranks #57 of 510 by total reports (3,209) and #138 of 275 by death-coded share (4.8%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#57
This breed, reports of 510
#138
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Spaniel (unspecified) has 3,209 reports now versus 3,163 in that prior snapshot: 46 more (1.5%).

Report change
+46
Death-coded reports
+3
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Spaniel (unspecified) changes

Total Reports

3,209

High report volume

Deaths Reported

155

of 3,209 reports

Death-coded share of reports

4.8%

Below-median death-coded share

Avg Age at Report

7.0 yr

13.8 kg avg weight

Breed Safety Scorecard

F (35/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate D
4.8%

Share of reports coded as a fatality

Euthanasia rate F
2.9%

Share of reports resulting in euthanasia

Full recovery rate F
25.4%

Share of reports coded "Recovered/Normal"

5-year trend F
+50%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Spaniel (unspecified) death-coded reports 4.8%
Cross-breed median

4.8% of 3,209 spaniel (unspecified) reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Spaniel (unspecified)'s death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

5% 50th percentile Higher share than 50% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Spaniel (unspecified) 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Spaniel (unspecified) among report-volume vs. death-rate peers

Every breed shown has at least 50 filed reports. Volume reflects how often a breed is reported, not how common it is; death rate is the share of a breed's own reports coded as a death outcome.

Source: FDA openFDA Animal & Veterinary Adverse Events database 2×2 strategic matrix plotting 30 entities by Total Reports (X) and Death Rate (%) (Y), with a crosshair dividing the plot into four quadrants. High volume, high death rateLow volume, high death rateHigh volume, low death rateLow volume, low death rate 020,00040,00060,00080,000100,000 0%5%10%15% Total Reports Death Rate (%) Spaniel (unspecified) vs. all breeds, report volume and death-coded share Retriever - Labrador-93675, 3.7%Crossbred Canine/dog-70591, 3.2%Domestic Shorthair-65226, 7.2%Dog (unknown)-48820, 8.8%Retriever - Golden-35980, 3.7%Shepherd Dog - German-32220, 4.4%Chihuahua-31521, 4.2%Terrier - Yorkshire-24924, 3.7%Shih Tzu-24405, 3.6%Boxer (German Boxer)-19405, 4.4%Beagle-17970, 3.6%Pit Bull-17865, 3.1%Shepherd Dog - Australian-16274, 3.7%Terrier (unspecified)-14058, 3.1%Maltese-13940, 3.2%Dachshund (unspecified)-13512, 4.6%Cat (unknown)-13248, 9.3%Terrier - Jack Russell-10423, 3.7%Collie - Border-10130, 4.3%Siberian Husky-9811, 4.5%Domestic Longhair-9615, 7%Pug-9224, 5.2%Spitz - German Pomeranian-9086, 4.9%Terrier - Bull - American Pit-8769, 4.7%Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)-7871, 3.6%Terrier - Boston-7737, 4.5%Spaniel - Cocker American-7640, 4%Domestic (unspecified)-7576, 13.4%Poodle (unspecified)-7534, 3.4%Schnauzer - Miniature-7513, 4.4%
Source: FDA openFDA Animal & Veterinary Adverse Events database
Average weight at time of report: 13.8 kg (30.4 lbs)

Top Reported Reactions

Vomiting 512
Lethargy (see also Central nervous system depression in 'Neurological') 291
Diarrhoea 270
Lack of efficacy - NOS 216
Lack of efficacy (endoparasite) - hookworm 201
Seizure NOS 181
Emesis 171
Lack of efficacy (endoparasite) - heartworm 125
Decreased appetite 110
Other abnormal test result NOS 109
Lack of efficacy (bacteria) - Borrelia 107
Anorexia 99
INEFFECTIVE, HEARTWORM LARVAE 97
Death by euthanasia 95
Lack of efficacy (ectoparasite) - flea 89

Most Referenced Drugs

Pyrantel Pamoate;Sarolaner 485
Trilostane 413
Oclacitinib Maleate 320
Ivermectin + Pyrantel As Pamoate Salt 284
Milbemycin Oxime + Spinosad 267
Moxidectin 265
Bedinvetmab 170
Afoxolaner 167
Sarolaner 161
Carprofen 139
Selamectin 96
Spinosad 80
Anti-Il31 Mab Mcs Lot #1283563 79
Maropitant Citrate 72
Gabapentin 61

Outcome Breakdown

Ongoing
1,144 (35.6%)
Outcome Unknown
1,017 (31.7%)
Recovered/Normal
815 (25.4%)
Euthanized
94 (2.9%)
Recovered with Sequela
81 (2.5%)
Died
61 (1.9%)

Gender Distribution

Female 1,587 (49.5%)
Male 1,553 (48.4%)
Unknown 58 (1.8%)
Mixed 11 (0.3%)

Reports by Year

Year Reports Trend
2010 3
2011 33
2012 134
2013 158
2014 236
2015 245
2016 258
2017 208
2018 210
2019 207
2020 209
2021 193
2022 226
2023 240
2024 324
2025 289
2026 36

Spaniel (unspecified): high-volume FDA adverse-event cohort

Signature read: 3,209 reports place Spaniel (unspecified) in the upper third of breed filing volume (#57 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Spaniel (unspecified) sits at #57 of 510 by report volume among all breeds and #51 of 298 among dog breeds, with 3,209 reports and 155 (4.8%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #138 of 275. Mean age at report: 7.0 years, average weight 13.8 kg (30.4 lbs).

Top reported signs: Vomiting (512), Lethargy (see also Central nervous system depression in 'Neurological') (291), Diarrhoea (270). Most-referenced drug: Pyrantel Pamoate;Sarolaner (485 reports), followed by Trilostane (413) and Oclacitinib Maleate (320).

Outcome coding on 3,212 status-recorded reports is dominated by Ongoing (35.6%). Annual submissions ranged 3-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Lhasa Apso
3,196 reports · 3.7% death-coded
Collie (unspecified)
3,131 reports · 4.8% death-coded
Terrier - Rat
3,078 reports · 4.3% death-coded
Mountain Dog - Bernese
3,012 reports · 4.2% death-coded
Mastiff
2,950 reports · 6.2% death-coded
Retriever (unspecified)
3,492 reports · 1.9% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Spaniel (unspecified) drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (4.8% death-coded here).

Scottish Fold Longhair 4.8% · Cat Bengal 4.6% · Cat Egyptian Mau 5.3% · Cat Siberian 4.2% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (13.8 kg here).

Wild cat 14.5 kg · Cat Monkey (unspecified) 11.6 kg · Monkey Primate (other) 10.1 kg · Primate Nigerian Dwarf 7.5 kg · Goat

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Spaniel (unspecified)? ▼
There are 3,209 adverse event reports involving Spaniel (unspecified) in the FDA database, of which 155 were death-coded (4.8% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Spaniel (unspecified) ranks #57 of 510 by report volume among all breeds PlainBreed indexes (#51 of 298 among dog breeds).
Where does Spaniel (unspecified) sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Spaniel (unspecified) is #57 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #51 of 298. Among breeds with at least 50 reports, its death-coded share ranks #138 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Spaniel (unspecified)? ▼
The most commonly reported adverse reactions for Spaniel (unspecified) are Vomiting (512 reports), Lethargy (see also Central nervous system depression in 'Neurological') (291 reports), Diarrhoea (270 reports), Lack of efficacy - NOS (216 reports), Lack of efficacy (endoparasite) - hookworm (201 reports).
What drugs are most frequently associated with Spaniel (unspecified) adverse events? ▼
The drugs most frequently referenced in Spaniel (unspecified) adverse event reports are Pyrantel Pamoate;Sarolaner (485 reports), Trilostane (413 reports), Oclacitinib Maleate (320 reports), Ivermectin + Pyrantel As Pamoate Salt (284 reports), Milbemycin Oxime + Spinosad (267 reports).
What is the average age of Spaniel (unspecified) in adverse event reports? ▼
The average age of Spaniel (unspecified) at the time of adverse event reports is 7.0 years, with an average weight of 13.8 kg (30.4 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Spaniel (unspecified) (Dog), extract as of July 2026 extract. 3,209 reports · 155 death-coded (4.8% of reports, not a mortality rate) · #57 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →