Total Reports
3,074
FDA CVM filings
Dog /
FDA CVM · 2025 release 3,074 reports on file
Spaniel (unspecified) - FDA Adverse Event Profile
Adverse-event records for Spaniel (unspecified) (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Spaniel (unspecified) is #60 by FDA report volume; 4.9% of its 3,074 reports (150) were death-coded.
- #60
- most-reported dog breed
- 4.9%
- death-coded report share
- 502
- Vomiting - top reaction
- 7.0 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
150
of 3,074 reports
Death Rate
4.9%
death-coded share
Avg Age at Report
7.0 yr
13.9 kg avg weight
Death-Coded Outcome Share
Spaniel (unspecified) death-coded reports 4.9%
Cross-breed median
4.9% of 3,074 spaniel (unspecified) reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 13.9 kg (30.6 lbs)
Top Reported Reactions
Vomiting 502
Lethargy (see also Central nervous system depression in 'Neurological') 291
Diarrhoea 262
Lack of efficacy - NOS 208
Lack of efficacy (endoparasite) - hookworm 187
Seizure NOS 173
Emesis 170
Lack of efficacy (endoparasite) - heartworm 120
Decreased appetite 107
Other abnormal test result NOS 106
Anorexia 98
INEFFECTIVE, HEARTWORM LARVAE 97
Lack of efficacy (bacteria) - Borrelia 96
Death by euthanasia 91
Lack of efficacy (ectoparasite) - flea 86
Most Referenced Drugs
Pyrantel Pamoate;Sarolaner 438
Trilostane 404
Oclacitinib Maleate 313
Ivermectin + Pyrantel As Pamoate Salt 281
Milbemycin Oxime + Spinosad 266
Moxidectin 246
Afoxolaner 163
Sarolaner 160
Bedinvetmab 149
Carprofen 130
Selamectin 94
Spinosad 80
Anti-Il31 Mab Mcs Lot #1283563 76
Maropitant Citrate 69
Gabapentin 51
Outcome Breakdown
Ongoing
1,069 (34.7%)
Outcome Unknown
984 (32.0%)
Recovered/Normal
794 (25.8%)
Euthanized
90 (2.9%)
Recovered with Sequela
80 (2.6%)
Died
60 (1.9%)
Gender Distribution
Female 1,524 (49.6%)
Male 1,484 (48.3%)
Unknown 55 (1.8%)
Mixed 11 (0.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 3 | |
| 2011 | 33 | |
| 2012 | 134 | |
| 2013 | 158 | |
| 2014 | 236 | |
| 2015 | 245 | |
| 2016 | 258 | |
| 2017 | 208 | |
| 2018 | 210 | |
| 2019 | 207 | |
| 2020 | 209 | |
| 2021 | 193 | |
| 2022 | 226 | |
| 2023 | 237 | |
| 2024 | 323 | |
| 2025 | 194 | |
Spaniel (unspecified) Pet Health Insights
Spaniel (unspecified) accounts for 3,074 FDA adverse event reports, ranking #60 by volume among dog breeds, with 150 reports (4.9%) coded as a death outcome. Mean age at report: 7.0 years, average weight 13.9 kg (30.6 lbs).
Top reported signs: Vomiting (502), Lethargy (see also Central nervous system depression in 'Neurological') (291), Diarrhoea (262). Most-referenced drug: Pyrantel Pamoate;Sarolaner (438 reports), followed by Trilostane (404) and Oclacitinib Maleate (313).
Outcome coding on 3,077 status-recorded reports is dominated by Ongoing (34.7%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Spaniel (unspecified)? ▼
There are 3,074 adverse event reports involving Spaniel (unspecified) in the FDA database, with 150 reports involving death (4.9% death rate). Spaniel (unspecified) ranks #60 by report volume.
What are the most common adverse reactions reported for Spaniel (unspecified)? ▼
The most commonly reported adverse reactions for Spaniel (unspecified) are Vomiting (502 reports), Lethargy (see also Central nervous system depression in 'Neurological') (291 reports), Diarrhoea (262 reports), Lack of efficacy - NOS (208 reports), Lack of efficacy (endoparasite) - hookworm (187 reports).
What drugs are most frequently associated with Spaniel (unspecified) adverse events? ▼
The drugs most frequently referenced in Spaniel (unspecified) adverse event reports are Pyrantel Pamoate;Sarolaner (438 reports), Trilostane (404 reports), Oclacitinib Maleate (313 reports), Ivermectin + Pyrantel As Pamoate Salt (281 reports), Milbemycin Oxime + Spinosad (266 reports).
What is the average age of Spaniel (unspecified) in adverse event reports? ▼
The average age of Spaniel (unspecified) at the time of adverse event reports is 7.0 years, with an average weight of 13.9 kg (30.6 lbs).
Does a high number of adverse event reports mean Spaniel (unspecified) is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Spaniel (unspecified) safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.